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CUSTOMIZED QUANTIFICATION OF HOST CELL PROTEIN WITH BIO-LAYER INTERFEROMETRY

Visste du att många läkemedel tillverkas av genmodifierade bakterier? Också ofta i genmodifierade celler från däggdjur, till exempel från kinesiska hamstrars äggstockar. Läkemedel producerade i celler är de snabbast växande på marknaden, och kan till exempel användas för att producera insulin eller ett COVID-19 vaccin. I denna studie har en ny metod utvecklats för att säkerställa att sådana läkeme

Evolving Health Expenditure Landscape of the BRICS Nations and Projections to 2025

Global health spending share of low/middle income countries continues its long-term growth. BRICS nations remain to be major drivers of such change since 1990s. Governmental, private and out-of-pocket health expenditures were analyzed based on WHO sources. Medium-term projections of national health spending to 2025 were provided based on macroeconomic budgetary excess growth model. In terms of per

Integrated conodont biostratigraphy and carbon isotope chemostratigraphy in the Lower–Middle Ordovician of southern Sweden reveals a complete record of the MDICE

One of the few and most complete records of the MDICE (Middle Darriwilian Isotope Carbon Excursion) is herein documented from Baltoscandia. Based on a core section penetrating the condensed Lower–Middle Ordovician succession (~46 m) on the island of Öland, southeastern Sweden, we provide an integrated scheme for carbon isotope chemostratigraphy (313 samples) and conodont biostratigraphy (29 sample

Global socio-technical regimes

This paper addresses the question why socio-technical transitions followsimilar trajectories in various parts of the world, even though the relevant material preconditions and institutional contexts vary greatly between different countries. It takes a critical stance on the implicit methodological nationalism in transition studies’ socio-technical regime concept and proposes an alternative ‘global

Global socio-technical regimes

This paper addresses the question why socio-technical transitions follow similar trajectories in various parts of the world, even though the relevant material preconditions and institutional contexts vary greatly between different regions and countries. It takes a critical stance on the implicit methodological nationalism in transition studies' socio-technical regime concept and proposes an altern

An interaction approach to global sourcing: A case study of IKEA

This study explores the process of global sourcing through a case of the Swedish furnishing retailer IKEA from an interaction perspective. With a point of departure in the streams of existing research on global sourcing and the internationalization process of firms through networks, a research question is proposed concerning supply network interactions as an influence in the global sourcing proces

The Role of Networks and Matching in Market Entry to Emerging Retail Markets

Purpose - The purpose is to investigate how a retailer identifies critical network actors and gains their support when entering an emerging market. and to examine the role of a firm's relationships with different types of actors on the new market. Design/methodology/approach - The study is of an exploratory nature, and based on an inductive and qualitative research method. A case study of IKEA's e

Concord and Conflict: the Hui Communities of Yunnan Society in a Historical Perspective

This dissertation studies the historical relation between the Muslim minority and the non-Muslim majority in Yunnan with a combined method: historical criticism supplemented by ethnological interpretation. This relation manifests in history dynamic and dialectical characteristics: concord and conflict. Concord can be found in the stable and balanced periods in the relevant socio-cultural aspects o

Perilipin A is essential for the translocation of hormone-sensitive lipase during lipolytic activation

A key step in lipolytic activation of adipocytes is the translocation of hormone-sensitive lipase (HSL) from the cytosol to the surface of the lipid storage droplet. Adipocytes from perilipin-null animals have an elevated basal rate of lipolysis compared with adipocytes from Wild-type mice, but fail to respond maximally to lipolytic stimuli. This defect is downstream of the p-adrenergic receptor-a

Trade and wage inequality: The mediating roles of occupations in Germany

Recent evidence shows that rising wage inequality in industrialized countries can partially be attributed to trade integration. However, it is unclear what the mechanisms behind this relationship are. Previous explanations pointed towards the displacement of mid-wage manufacturing workers as a response to rising imports. But for Germany it has been shown that rising exports likewise create manufac

Emissions of halogenated compounds in east asia determined from measurements at Jeju Island, Korea

High-frequency in situ measurements at Gosan (Jeju Island, Korea) during November 2007 to December 2008 have been combined with interspecies correlation analysis to estimate national emissions of halogenated compounds (HCs) in East Asia, including the chlorofluorocarbons (CFCs), halons, hydrochlorofluorocarbons (HCFCs), hydrofluorocarbons (HFCs), perfluorocarbons (PFCs), sulfur hexafluoride (SF6),

Prospects for Desalination as a Water Supply Method

In this paper, four major parameters of fresh water production from saline sources are discussed. The parameters are desalination technology type, water sources input type, energy sources and productions cost per cubic meter. Five different types of desalination technology are presented and bench-marked for long-term use. RO and MSF are dominant technologies. Six different input water sources are

Relationship between precipitation and 10Be and impacts on soil dynamics

Meteoric beryllium-10 (10Be) is commonly used as a proxy of landscape dynamics (erosion and sedimentation rates) and soil development. Soil represents the first-stage reservoir of meteoric 10Be, and variability in the concentration of the isotope in soils may be affected by soil properties and atmospheric deposition. Although many investigations have targeted this issue, there are still problems i