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Your search for "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" yielded 194725 hits

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The critical stress intensity factor for hydrided zirconium-alloys is calculated using a Dugdale type model for a finite crack. The hydride platelets are assumed to surround the ends of the crack. They are located in the process region of the crack tip. The model is used to calculate the temperature dependence of the critical stress intensity factor and the results are compared with measurements p

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Crack paths in an elastic layer on top of a substrate are considered. Crack growth is initiated from an edge crack in the layer. The plane of the initially straight crack forms an angle to the free surface. The load consists of a pair of forces applied at the crack mouth and parallel to the interface. Crack paths are calculated using a boundary element method. Crack growth is assumed to proceed al

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The maternally transmitted bacterium Wolbachia pipientis is well known for spreading and persisting in insect populations through manipulation of the fitness of its host. Here, we identify three new Wolbachia pipientis strains, wHho, wHho2 and wHho3, infecting Hyposoter horticola, a specialist wasp parasitoid of the Glanville fritillary butterfly. The wHho strain (ST435) infects about 50% of the i

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Bicyclusbutterflies are key species for studies ofwing pattern development, phenotypic plasticity, speciationand the genetics of Lepidoptera. One of the key endosymbi-onts in butterflies, the alpha-ProteobacteriumWolbachiapipientis, is affecting many of these biological processes;however, Bicyclusbutterflies have not been investigated sys-tematically as hosts toWolbachia.Inthisstudy,wescreenforWo

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In this work, we study the clutter and multi-path propagation in a time-domain millimeter-wave reflectometry setup, used for material characterization or short-range imaging. The signal energy and fidelity factor of the different reflection components is analyzed in dependence of the distance from the target. Due to the change in pulse distortion in the multi-path components, the system impulse re

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The compensatory growth potential of a grazed fungal biomass was mathematically expressed as a function of patchiness in its distribution and demonstrated in an experiment using the fungivorous collembolan Onychiurus armatus and the soil fungi Verticillium bulbillosum and Penicillium spinulosum. The model addresses the regrowth potential in relation to patch fragmentation, travelling time and cons

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Purpose: Reliable data on familial risks are important for clinical counseling and cancer genetics. However, population-based studies on familial soft tissue tumors are limited, which we will examine. Methods: Adjusted standardized incidence ratios (SIRs), calculated from the nation-wide Swedish Family Cancer Database, were used to measure the familial risk. Results: There were 17 offspring-parent

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Dark matter direct detection experiments need to know the local phase space density of dark matter fdm(r,v,t) in order to derive dark matter particle properties. To date, calculations for fdm(r,v,t) have been based on simulations that model the dark matter alone. Here we include the influence of the baryonic matter. We find that a star/gas disc at high redshift (z∼1) causes merging satellites to b

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The standard Godunov type method used in computational fluid dynamics shows accuracy problems for low Mach number flows and for the kinetic energy at the highest wave numbers resolvable on a given grid. Both drawbacks become visible when simulating the decay of isotropic turbulence at the low Mach numbers typical for the respective experimental investigations. A modification to cure both problems

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X-ray scattering imaging can provide complementary information to conventional absorption based radiographic imaging about the unresolved microstructures of a sample. The scattering signal can be accessed with various methods based on coherent illumination, which span from self-imaging to speckle scanning. The directional sensitivity of the existing real space imaging methods is limited to a few d

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The interior of living cells is a dense and polydisperse suspension of macromolecules. Such a complex system challenges an understanding in terms of colloidal suspensions. As a fundamental test we employ neutron spectroscopy to measure the diffusion of tracer proteins (immunoglobulins) in a cell-like environment (cell lysate) with explicit

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The model peptides A 8 K and A 10 K self-assemble in water into ca. 100 nm long ribbon-like aggregates. These structure

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We present an implementation of heavy quarkonium production within a perturbative QCD cascade based on the Color Dipole Cascade model. We consider the processes most relevant in the context of the ψ′ surplus at the Tevatron; g → ψ′ and c → ψ′ in the color-singlet model and g → ψ′ through the color-octet mechanism. Our implementation is, however, easily extendible to other quarkonia and other produ

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Circadian rhythms are ubiquitous in eukaryotes, and coordinate numerous aspects of behaviour, physiology and metabolism, from sleep/wake cycles in mammals to growth and photosynthesis in plants. This daily timekeeping is thought to be driven by transcriptionaltranslational feedback loops, whereby rhythmic expression of clock- gene products regulates the expression of associated genes in approximat