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Background: Exertional breathlessness is a cardinal symptom of cardiorespiratory disease. Research Question: How does breathlessness abnormality, graded using normative reference equations during cardiopulmonary exercise testing (CPET), relate to self-reported and physiologic responses in people with chronic airflow limitation (CAL)? Study Design and Methods: An analysis was done of people aged ≥
The ATLAS detector is installed in its experimental cavern at Point 1 of the CERN Large Hadron Collider. During Run 2 of the LHC, a luminosity of ℒ = 2 × 1034 cm-2 s-1 was routinely achieved at the start of fills, twice the design luminosity. For Run 3, accelerator improvements, notably luminosity levelling, allow sustained running at an instantaneous luminosity of ℒ = 2 × 1034 cm-2 s-1, with an a
Introduction: Antimicrobial resistance (AMR) represents a persistent and ascensive global threat influenced by antibiotic misuse and overuse. In the Romanian context, patterns of antibiotic consumption and resistance within the healthcare system are marked in the red scenario on the European map. General practitioners and pharmacists, among others, play a major role in stewardship towards AMR.Aim:
Abstract – Introduction: Peripheral intravenous catheterization is commonly required in sick neonates but remains challenging due to small vessels, leading to multiple attempts and complications. This review evaluated the benefits and harms of device-assisted techniques versus standard technique. Methods: We searched MEDLINE, Embase, CENTRAL, Cochrane Reviews, WHO ICTRP, and ClinicalTrials.gov (Oc
Objective: Worse women's outcomes after elective standard endovascular aneurysm repair have been widely reported. Similar data have surfaced from cohorts undergoing fenestrated and branched repair; however, studies reporting from a sex perspective are rare and mostly limited to single centre designs. This study aimed to examine survival following nationwide complex endovascular repair according to
OBJECTIVE: Infective native aneurysms of the femoropopliteal arteries (INA-FPs) are rare and mostly reported in intravenous drug users (IVDU). This study aimed to summarize all cases of INA-FPs presented in the literature, to describe patient characteristics, microbiology, treatments and outcomes, and compare IVDU with non-IVDU patients.METHODS: A systematic search of PubMed, ScienceDirect, Embase
Introduction: Malaria remains a persistent challenge in global health, disproportionately affecting populations in endemic regions (eg, sub-Saharan Africa). Despite decades of international collaborative efforts, malaria continues to claim hundreds of thousands of lives each year, with young children and pregnant women enduring the heaviest burden. This concise review aimed to provide an up-to-dat
Bouchra Khalili occupies three theater stages, offering the present a sensitive echo of hidden memories and forgotten stories.With her project Asterisms (Fig. 1 to 3), Bouchra Khalili, visual artist invited to the 2025 edition of the Festival d’Automne, successively invests three theater stages to explore the links between the representation of buried histories, performance, and moving images. Dra
We present new observations from CHEOPS (CHaracterising ExOPlanet Satellite) and TESS (Transiting Exoplanet Survey Satellite) to clarify the architecture of the planetary system hosted by the old Galactic thick disc star TOI-561. Our global analysis, which also includes previously published photometric and radial velocity data, incontrovertibly proves that TOI-561 is hosting at least four transiti
Southern Kazakhstan, particularly the Zhambyl Region, is facing increasing groundwater stress due to climate change, degradation of irrigation infrastructure, and unsustainable water use. Despite substantial renewable groundwater reserves (8.33 km3/year), irrigation still relies on ephemeral surface flow. This study delineates priority zones for Managed Aquifer Recharge (MAR) using a GIS-based Mul
Background: Neuroimaging with magnetic resonance imaging (MRI) may assist clinicians in evaluating brain injury and optimising care in comatose adults resuscitated after out-of-hospital cardiac arrest (OHCA). However, contemporary international data on its use are lacking. Aim: The primary aim was to compare the patient characteristics, early postresuscitation care, and neurological outcomes of pa
Background Primary ciliary dyskinesia (PCD) represents a group of rare hereditary disorders characterised by deficient ciliary airway clearance that can be associated with laterality defects. We aimed to describe the underlying gene defects, geographical differences in genotypes and their relationship to diagnostic findings and clinical phenotypes. Methods Genetic variants and clinical findings (a
Background: Drug-related problems are common in older individuals. A medication reconciliation has the goal of identifying and maintaining an accurate medication list and can serve to prevent drug-related problems caused by discrepancies. Objectives: This study aimed to explore primary care physicians’ intentions towards performing medication reconciliation in patients with multimorbidity using a
Objectives Assessment of Different NEoplasias in the adneXa (ADNEX) and Risk of Malignancy Index (RMI) are models that estimate the risk of malignancy in ovarian masses based on clinical and ultrasound information. The aim is to perform a meta-analysis of studies that compared the performance of the two models in the same patients (‘head-to-head comparison’). Design Systematic review and meta-anal
BACKGROUND: Kinetic energy (KE) of intracardiac blood flow reflects myocardial work spent on accelerating blood and provides a mechanistic window into diastolic filling dynamics. Diastolic dysfunction may represent an early stage in the development of heart failure (HF). Here we evaluated the hemodynamic effects of impaired diastolic function in subjects with and without HF, testing the hypothesis
Background: Research on eldercare has been dominated by a provider-oriented perspective, concerned with the conditions and views of care providers. There are striking differences compared with the field of disability studies, where help is framed as part of a larger project of having a daily life and being included in society. Pilot interviews indicate that older people develop active strategies t
Title: The Power to be Creative - Unveiling the Influence of Power on Creativity Within Open Innovation Environments Authors: Savana Alves Pires and Arianna Isabelle Ragonese Purpose: This thesis aimed to explore the impact of power on creativity within an open innovation environment. Methodology: We employed a qualitative study utilizing the interpretivist tradition while using an abductive a
