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Transcriptional regulation and effects on differentiation by LMO proteins and the basic helix-loop-helix factors TAL1 and HEN1

Acute lymphoblastic leukemia (ALL) is the most widespread type of cancer, as well as the most frequent leukemia in children. Malignant ALL cells originate from normal T lymphocytes or B cells that are blocked at immature stages of differentiation. Since T cell lineage derived ALL in children is associated with various unfavorable features, it is no surprise that childhood T lineage ALL have been r

E-Business in a Vendor-Customer Interface: Implications for Logistics Concerning Physical Distribution and Information Management

In today’s business environment the use of e-business is gradually becoming more common. This paper sets out to highlight the implications for logistical operations and possible future developments in a vendor-customer relationship (B2B environment) when e-business is introduced. The paper implies that use of an e-business solution does not necessarily mean any changes in the physical distribution

Lifetime measurements for excited states of rare-earth atoms using pulse modulation of a cw dye-laser beam

By pulse-modulating a cw dye-laser beam and employing the delayed-coincidence technique, we have determined the natural radiative lifetimes of a number of atomic states in rare-earth atoms Eu, Dy, and Yb. In the measurements, which were performed on an atomic beam, exponential decay curves with good statistics were obtained using short measuring times. The general features of the technique are dis

Stakeholder relations a way of viewing your alliances

Using stakeholder relationships in order to understand alliances could possibly be one way of getting a new take on alliances and why they so often fail. During the LUSAX research a number of factors have emerged that can be said to influence alliances. Having dedicated functions to run and monitor the alliances, as well as having good relationships with partners that materializes into trust are t

Amputation for vascular disease. Prognostic factors for healing, long-term outcome and costs.

Popular Abstract in Swedish I Sverige utförs cirka 3500 benamputationer varje år. Över 90% av alla amputationer görs på grund av kärlsjukdomar, där förträngningar i blodkärlen försämrar blodflödet med vävnadsdöd och vanligen kallbrand som följd. Det finns i huvudsak tre faktorer som ökar risken för amputation på grund av kärlsjukdom; ålder *80 år, rökning och diabetes. Om man inte tillhör någon avGeneral characteristics and outcome was evaluated in 177 consecutive patients who underwent a major amputation in a defined population. Smoking and diabetes lowered the mean amputation age. Healing failure at six months was seen in 24% of transtibial and in 11% of transfemoral amputees. Preoperative absence of gangrene and hemoglobin >120 g/L increased the risk of healing failure. Six months after