Search results

Filter

Filetype

Your search for "*" yielded 546946 hits

Interjections as viewed by Latin grammarians

This article is an overview of the various aspects characterizing the interjection - probably the most controversial linguistic unit in the history of grammatical tradition and modern linguistics - as Latin grammarians outlined them, especially in the postclassical and late antiquity. The corpus employed for the purposes of this study is Henricus Keil's Grammatici Latini, a most valuable and uniqu

Endogenous NADPH-dependent aldose reductase activity influences product formation during xylose consumption in recombinant Saccharomyces cerevisiae

Introduction of the xylose pathway from Pichia stipitis into Saccharomyces cerevisiae enables xylose utilization in recombinant S. cerevisiae. However, xylitol is a major by-product. An endogenous aldo-keto reductase, encoded by the GRE3 gene, was expressed at different levels in recombinant S. cerevisiae strains to investigate its effect on xylose utilization. In a recombinant S. cerevisiae strai

T-cells in COPD to help or harm? A study of T-cells in COPD patients and related aspects of T-cell function in vitro

Popular Abstract in Swedish Patienter med kroniskt obstruktiv lungsjukdom, KOL, har en försämrad lungfunktion och lider av bronkit och andnöd. Dessa symptom beror troligtvis på en ständigt pågående inflammation i lungan som dels leder till ökad slemproduktion och förträngning av luftrören, dels till emfysem dvs. nedbrytning av lungvävnaden vilket försämrar gasutbytet i lungan. Cigarrettrökning är Chronic obstructive pulmonary disease, COPD, is manifested by chronic airflow limitation due to inflammation and tissue destruction in the lungs. COPD is caused primarily by smoking and with increasing cigarette consumption in the world, the prevalence for COPD will most probably increase in the future. The chronic inflammation in the lungs of these patients is thought to drive the pathogenesis fo

Correlation between isoform composition of the 17 kDa myosin light chain and maximal shortening velocity in smooth muscle

The relation between the isoform distribution of the myosin 17 kDa essential light chain (LC17) and the mechanical properties of smooth muscle was investigated. The relative content of the basic (LC17b) and acidic (LC17a) isoelectric variants of the 17 kDa myosin light chain was determined in different mammalian smooth muscle tissues. The relative content of LC17b varied between muscles: rabbit re

Cost-effectiveness of risedronate for the treatment of osteoporosis and prevention of fractures in postmenopausal women

Randomized, double-blind, controlled studies have shown that treatment with risedronate reduces the risk of vertebral fracture in postmenopausal women with established vertebral osteoporosis. They also show that the drug decreases the risk of non-vertebral fractures in women with osteoporosis. The aim of this study was to investigate the cost-effectiveness of risedronate in postmenopausal women wi

Histologic grading in breast cancer--reproducibility between seven pathologic departments. South Sweden Breast Cancer Group

Histologic grade, including tubular formations, nuclear grade, and mitotic activity, is a well-documented prognostic factor in breast cancer. In comparison with other prognostic parameters, the evaluation of histologic grade is cheap and can be performed, in principle, in all cases of breast cancer. One possible disadvantage is that the evaluation may vary between different pathological department

Long-term regulation of cyclic nucleotide phosphodiesterase type 3B and 4 in 3T3-L1 adipocytes.

Phosphodiesterase 3B (PDE3B), is known to play an important role in acute insulin and cAMP-mediated regulation of lipid metabolism, and PDE4 are the main PDE types expressed in adipocytes. Here, we show that members of all PDE4 isoforms are expressed in 3T3-L1 and primary mouse adipocytes. Long-term treatment of 3T3-L1 adipocytes with insulin induced up-regulation of PDE3B and PDE4D in a phosphati

Effect of rock climbing on the calcicolous lichen community of limestone cliffs in the northern Swiss Jura Mountains

Exposed limestone cliffs in the Swiss Jura Mountains harbour a diverse lichen community with some rare species. Sport climbing has recently increased in popularity on these cliffs. We examined the effect of sport climbing on calcicolous lichens by assessing species diversity and cover of lichens in climbed and unclimbed areas of 10 isolated cliffs in the northern Swiss Jura Mountains. We also inve

DNA microarray analysis of chromosomal susceptibility regions to identify candidate genes for allergic disease: A pilot study

Objective-To examine whether DNA microarray analysis of chromosomal susceptibility regions for allergy can help to identify candidate genes. Material and Methods-Nasal biopsies were obtained from 23 patients with allergic rhinitis and 12 healthy controls. RNA was extracted from the biopsies and pooled into three patient and three control pools. These were then analysed in duplicate with DNA microa

Infection of BALB/c A mice by spiral and coccoid forms of Helicobacter pylori

Helicobacter pylori exists in two different morphological forms, spiral and coccoid. This study demonstrated that both forms can infect BALB/c A mice. The animals were inoculated orally three times at 2-day intervals with 10(8) cfu of both spiral and coccoid forms of strain CCUG 17874 (NCTC 11637), strain 25 and strain 553/93. Infection was followed over a 30-week period by histological scoring of

Preterm birth in Sweden 1973-2001: Rate, subgroups, and effect of changing patterns in multiple births, maternal age, and smoking

Background. The objectives of this report are to evaluate changes in the preterm birth rate in Sweden 1973-2001. Furthermore, describe the proportion of spontaneous and indicated preterm births and assess risk factors for the subgroups of preterm birth during the period from 1991 to 2001. Methods. A population-based register study of all births occurring in Sweden from 1973 to 2001 registered in t

Pregnancy outcomes during treatment with interferon beta-1a in patients with multiple sclerosis.

Background: Although patients with multiple sclerosis (MS) are advised to stop interferon (IFN) beta-1a therapy before becoming pregnant, some patients become pregnant while on treatment. Methods: We examined individual patient data from eight clinical trials with IFN beta-1a. Results: Of 3,361 women in the studies, 69 pregnancies were reported, of which 41 were patients receiving (or who had stop