Context and Objective: Metabolic and body compositional consequences of GH deficiency (GHD) in adults are associated with a phenotype similar to the metabolic syndrome (MetS). Patients: We assessed MetS prevalence in adult GHD patients (n = 2531) enrolled in the Hypopituitary Control and Complications Study. Prevalence was assessed at baseline and after 3 yr of GH replacement in a subset of 346 ad

The aim of the present study was to investigate the long-term impact of prognostic factors in invasive lobular carcinoma (ILC) of the breast, with a primary focus on Ki67 and histological grade, alone and in combination with estrogen receptor (ER).

The research literature suggests that physicians' attitudes regarding disclosing a diagnosis of cancer have changed, from nondisclosure to full disclosure. Physicians' attitudes towards disclosing a patient's prognosis are likewise said to have changed, although not to the same degree. The aim of this study was to identify inherent challenges in communicating information about imminent death. It i

Motivated by repeated price spikes and crashes over the last decade, we investigate whether the intensive investment activities of commodity index traders(CITs) have destabilized agricultural futures markets. Using a stochastic volatility model, we treat conditional volatility as an unobserved component, and analyze whether it has been affected by the expected and unexpected open interest of CITs.

We investigated changes of postural responses to repeated bipolar galvanic vestibular stimulation on 5 consecutive days and once again after 3 months. Subjects consisted of 21 healthy volunteers. Except for the first day did the induced torque variance in response to galvanic vestibular stimulation not decrease {within} each test session, but there was a major reduction {from day to day} (p< 0.001

The detailed interactions of nitrogen oxides with ice are of fundamental interest and relevance for chemistry in cold regions of the atmosphere. Here, the interactions of NO, NO2, N2O4, and N2O5 with ice surfaces at temperatures between 93 and 180 K are investigated with molecular beam techniques. Surface collisions are observed to result in efficient transfer of kinetic energy and trapping of mol

PURPOSE: The Dutch national guideline for Cardiovascular Risk Management advised in 2006 initiation of statin therapy in new patients with simvastatin. After the introduction of this guideline several measures were taken to increase the prescription of simvastatin in general practice. The aim of this paper is to describe the trend and interpractice variation in the relative share of simvastatin in

The purpose of this work is to present results from an ongoing study on how the presence of surfaces influences the buckling properties of nanowires. This study is performed using molecular statics simulations where the interatomic interaction is modelled using an embedded atom potential (EAM) fitted to gold properties. The considered nanowires have rectangular cross sections with cross sectional

Objective. To determine whether low-dose ciclosporin was a more effective corticosteroid-sparing agent than AZA in patients with SLE. Methods. Patients with SLE requiring a change or initiation of a corticosteroid-sparing agent and who were taking >/=15 mg of prednisolone/day were randomized to receive either ciclosporin or AZA during this 12-month open-label multi-centre trial. There were strict

De senaste decenniernas samhällsvetenskapliga debatt har kretsat kring föreställningen att det skett ett epokgörande skifte. Industrisamhället har övergått i ett postindustriellt samhälle och moderniteten har ersatts av ett postmodernt tillstånd. Postmodernismen har ansetts markera ett slut för alla stora berättelser, ideologier och politiska projekt om emancipation. Denna era har på så sätt också

Variations in serum prostate-specific antigen (PSA) have been ascribed to A/G nucleotide polymorphisms located at -158 bp (rs266882) and -4643 bp (rs925013), relative to the transcription start site within the promoter of the PSA gene. PSA is also an androgen receptor target (AR) gene and polymorphisms in AR gene are known to affect AR function. Our objective was to compare the impact of these A/G

Asymptotics plays a crucial role in statistics. The theory of asymptotic consistency of Bayesian nonparametric procedures has been developed by many authors, including Schwartz (1965), Barron, Schervish and Wasserman (1999), Ghosal, Ghosh and Ramamoorthi (1999), Ghosal, Ghosh and van der Vaart (2000), Shen and Wasserman (2001), Walker and Hjort (2001), Walker (2004), Ghosal and van der Vaart (2007

Nuclear quadrupole resonance (NQR) offers an unequivocal method of detecting hidden narcotics and explosives. Unfortunately, the practical use of NQR is restricted by the low signal-to-noise ratio (SNR) and means to improve the SNR are vital to enable a rapid, reliable and convenient system. In this correspondence, we develop two multichannel detectors to counter the typically present radio freque

Recension av Semy Kahan: Röster för fred. Nya perspektiv på den israelisk-palestinska konflikten.

Medarbetarna på den dagliga verksamheten Tryckolera är med hela vägen i projektet Mobility and Learning Environments. Visst blir de utforskade men de får själva något rejält tillbaka, betonar forskaren Arne Svensk. Det har varit en svindlande kunskapsresa för alla inblandade. Nu behövs hjälp av andra forskare för att tolka vad som hänt under processen.