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The work presented in this thesis demonstrates the application of electrochemical methods for probing the dynamics of cellular metabolism in prokaryotic and eukaryotic cells. The main part of the work has been done using genetically modified strains of yeast. Employing baker’s yeast, S. cerevisiae, as a model organism, it was demonstrated how an amperometric method can be utilized for real-time in
Popular Abstract in English European dry extensive grasslands are biodiversity hotspots which are severely threatened by land use intensification and abandonment. In order to plan efficient conservation actions it is necessary to collect information on the current status of grasslands, their species diversity and prevailing environmental conditions. Remote sensing technology in combination with grAs a consequence of agricultural intensification, large areas of species-rich grasslands have been lost and farmland biodiversity has declined. Previous studies have shown that the continuity of grazing management can have a significant influence on the environmental conditions and the levels of plant species diversity in grassland habitats. The preservation of species-rich grasslands has become a
Popular Abstract in Swedish En europeisk köpoption ger innehavaren rätten, men inte skyldigheten, att köpa en underliggande tillgång till ett visst pris, lösenpriset, vid ett bestämt datum, lösendagen. En europeisk säljoption definieras på motsvarande sätt: den ger innehavaren rätten, men inte skyldigheten att sälja den underliggande tillgången. En teori för hur denna typ av finansiella kontrakt sThis thesis consists of three chapters devoted to both empirical and theoretical aspects of option pricing. The first chapter investigates the market for European options on the Swedish OMX index using daily data for the period 1993-2000. The assumption of constant volatility of the returns underlying the Black and Scholes option pricing formula is assessed by extracting the volatilities implied
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Recent statistics and terror events testify an increased vulnerability of distribution networks. Antagonistic threats as theft, counterfeiting, contamination and terror are burdening supply chains with unexpected costs in form of lost cargo, production downtimes, lower customer satisfaction, and higher transportation costs. Society is also worried about the possibility for terrorists to exploit su
In the autumn of 2011, the course “The City: Boundary Transgressions and Visual Expressions” was given for the first time. Formally placed at the Division of Art History and Visual Studies, the course is a collaboration with the Division of Social Anthropology and is directed towards students from a range of disciplines within the fields of the humanities and social sciences. The course includes
A procedure for making accurate matrix corrections in PIXE analyses of samples of intermediate thickness has been developed. The transmission of a collimated X-ray beam through different parts of the sample is measured with a Si(Li) detector to determine the thickness and shape of the sample. Experiments have been performed using uniform polymer foils doped with known concentrations of different e
Popular Abstract in Swedish Parkinsons sjukdom karaktäriseras av en progressiv degenerering av dopamin-producerande celler. Avsaknad av dopamin resulterar i kardinalsymptomen bradykinesi (långsamma rörelser), akinesi (avsaknad av rörelser), rigiditet (muskelstelhet) samt tremor (lågfrekventa darrningar i händerna, även kallad ”pillertrillar” rörelser). Den mest framgångsrika behandlingen består avThis study explores the role of transcriptional regulation important in the development of L-DOPA-induced dyskinesia in a rat model of Parkinson’s disease. In patients with Parkinson’s disease, dyskinesia is one of the most difficult complications of the DA-replacement therapy by L-DOPA. The underlying mechanisms are still unknown, but a role of abnormal striatal plasticity has been proposed. The
From a paradigmatic understanding of tourism, the thing about tourism experiences is that they differ from everyday life. You experience different places, see different people, get to know different ways of doing things, and so on. To do tourism, then, is to experience a series of changes from the ordinary. Several things change in the course of the making and consumption of a tourism product. For
Popular Abstract in Swedish För att skydda sig mot infektioner har människan ett välutvecklat immunförsvar. I immunförsvaret ingår många olika celler och proteiner (äggviteämnen). Till exempel finns det celler som producerar antikroppar som specifikt känner igen bakterier och virus som en människa har utsatts för vid en tidigare infektion. Det finns också speciella celler som kan fagocytera (äta uMany microorganisms have developed mechanisms to protect themselves against attack from the complement system of the host. One possible mechanism for a microorganism to evade complement attack is to bind a human complement regulator, which may allow the microorganism to down-regulate complement activation. This thesis describes studies of such interactions between human C4b-binding protein (C4BP),
