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Aquaporins (AQPs) are a family of transmembrane water channels expressed in all living organisms. AQPs facilitate osmotically driven water flux across biological membranes and, in some cases, the movement of small molecules (such as glycerol, urea, CO2, NH3, H2O2). Protein–protein interactions play essential roles in protein regulation and function. This review provides a comprehensive overview of
There has been a public debate among academics and politicians of whether Hungary should be required to join the European Public Prosecutor’s Office as a condition to receive EU funds according to the different milestones. As the EPPO is tasked with investigating fraud and mismanagement of EU funds, it is well-placed to address the allegations of serious corruption that the Hungarian Government is
PURPOSE: Evaluate patient-reported knee function after arthroscopic partial meniscectomy (APM) and meniscus suture repair in two different age cohorts compared with a normal population.METHOD: Arthroscopic meniscus surgery was performed on 421 patients at Skåne University Hospital from 2010 to 2014, with a mean (SD) follow-up of 4.2 (1.4) years. Patients and controls were divided into two age coho
The impacts of adverse weather conditions on railway systems can lead to large delays and cancellationsacross the entire network. In this paper, we aim to understand the relationship between weather andtrain disruptions (i.e. cancellations and large delays) across the entire Swedish railway network for theyears 2011-2019. Using railway operations data and snow depth, temperature, precipitation, an
Background Chromium (Cr) contact allergy is frequent in many industrialized countries. The knowledge of the factors that can influence percutaneous penetration is very important assessing the risk of human exposure. Objective The aim of the study was to compare the concentration of Cr in various skin layers using 2 different vehicles. Methods Full-thickness (approximately 1 mm) porcine ear skin wa
High-quality simulated data is crucial for particle physics discoveries. Therefore, parton shower algorithms are a major building block of the data synthesis in event generator programs. However, the core algorithms used to generate parton showers have barely changed since the 1980s. With quantum computers’ rapid and continuous development, dedicated algorithms are required to exploit the potentia
ATP7B is a human copper-transporting P1B-type ATPase that is involved in copper homeostasis and resistance to platinum drugs in cancer cells. ATP7B consists of a copper-transporting core and a regulatory N-terminal tail that contains six metal-binding domains (MBD1-6) connected by linker regions. The MBDs can bind copper, which changes the dynamics of the regulatory domain and activates the protei
Akvifären Alnarpsdalen är 6 - 10 km bred och sträcker sig från Skivarp i sydost till Löddeköpinge i nordväst och vidare ut i Öresund. Trots att flertalet kommuner i Skåne numera försörjs med vatten från Vombsjön eller Bolmen finns det kommuner, industrier och jordbrukare som använder vatten från Alnarpsdalen.Det finns ett antal frågor som kan ställas gällande Alnarpsdalen, till exempel hur mycket
Background: There is growing attention and policy debate about the sharing of personal information that the modernization of electricity grids requires. This is particularly important for big data management in smart grids that needs access to data generated and sent through devices such as smart meters. Using the Nordic Countries as a case study, this study investigates the willingness of people
Slaughter transportation of pigs can be considered a high-risk occupation, but has received very little scientific attention. We investigated the effect of a training intervention on transport drivers’ physical workload, in terms of postures and movements, and time efficiency during loading of finishing pigs for slaughter transport. The training targeted pig handling and ergonomic working principl
The influence of growth conditions on the layer orientation, domain structure and crystal structure of gadolinium oxide (Gd2O3) on silicon (001) has been investigated. Gd2O3 was grown at low (250°C) and high (850°C) temperatures with different oxygen partial pressure as well as a temperature ramp up during growth. At low temperature, the cubic bixbyite type of crystal structure with space group Ia
Lignin, the most abundant aromatic biopolymer on Earth, is often considered a biorefinery by-product, despite its potential to be valorized into high-added-value chemicals and fuels. In this work, an integrated superstructure-based optimization model was set up and optimized using mixed-integer non-linear programming for the conversion of technical lignin to three main biobased products: aromatic
BACKGROUND: In Southeast-Asia, where many conditions associated with dissemination of ESBL-producing Enterobacterales (ESBL-E) in the community are met, data from the community are scarce but show high ESBL-E carriage prevalence. Maternal ESBL-E colonization is considered a risk factor for neonatal colonization, which is the first step towards developing neonatal sepsis. Despite this, ESBL-E carri
Prostate-specific antigen (PSA) is a serine protease belonging to the human glandular kallikrein gene family [1–3]. The expression of PSA is mainly androgen dependent, and the detection of very high expression levels is restricted to the prostate tissue, but extraprostatic production at much lower levels has been demonstrated in several other tissues such as normal and malignant breast epithelium,
A radial flow cell (RFC, inlet tube radius 0.95 mm and gaps of 1–4.2 mm) was used to investigate the removal of two thin (80–230 µm thick) model soil layers from glass and 304 stainless steel substrates by the flow of water at 20 °C. Under the flow conditions employed (Reynolds numbers 200–1400), inertial effects give rise to recirculation zones and regions of high shear stress on the bottom, soil
Objectives: The introduction of time-dependent reperfusion therapies in acute ischemic stroke has increased the need for early identification. We explore the safety and feasibility of STROKE ALARM which detects sudden arm paresis, the most frequent symptom in stroke. Materials and methods: Consecutive patients admitted with a stroke or TIA at Skåne University Hospital were screened according to in
Introduction: Cycling as a means of transport or recreational activity is increasing in popularity in Ireland. However, increasing numbers of cyclists may lead to an increased number of bicycle collisions and fatalities. The Road Safety Authority is the statutory body for road safety in Ireland but uses police data alone to collate cycling collision statistics. This may lead to an underestimation
