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Hyponatremia, hypernatremia and impairment of functional, psychological and sexual domains

Objective: To determine the influence of serum sodium on physical, psychologic and sexual function. Methods: This is a cross-sectional survey on 3340 community-dwelling men aged 40–79 years from a prospective cohort study in eight European countries, the European Male Ageing Study (EMAS). Participants filled-out the Short Form-36 (SF-36), the Physical Activity Scale for the Elderly (PASE), and the

Flexibility and Function of Distal Substrate-Binding Tryptophans in the Blue Mussel β-Mannanase MeMan5A and Their Role in Hydrolysis and Transglycosylation

β-Mannanases hydrolyze β-mannans, important components of plant and microalgae cell walls. Retaining β-mannanases can also catalyze transglycosylation, forming new β-mannosidic bonds that are applicable for synthesis. This study focused on the blue mussel (Mytilus edulis) GH5_10 β-mannanase MeMan5A, which contains two semi-conserved tryptophans (W240 and W281) in the distal subsite +2 of its activ

Prevalence of women with breast implants in Sweden : a study based on the population-based mammography screening programme

BACKGROUND: Knowledge about the prevalence of women with breast implants is paramount in calculations of risks and in estimations of effects on screening and breast cancer treatment. Most of the estimations of prevalence made to date are rough and often based on sales data. The main aim of this study was to calculate the prevalence of breast implants in Swedish women. The secondary aim was to inve

Benthic foraminiferal investigations in Middle to Late Quaternary sections of Kongsfjordhallet, north-west Svalbard

Stratigraphic sites in north-west Svalbard record at least six significant glacial advances in the last 200 Ky, and sediments deposited under locally high relative sea level during intervening interstadials or interglacials contain abundant benthic foraminifera. We present a biostratigraphic record from the Kongsfjordhallet site in the Kongsfjorden area that covers five high relative sea-level eve

New Urbanism : Med småstaden som förebild för förorten

Kapitalet innehåller en kort introduktion till den amerikanska stadsbyggnadsrörelsen New Urbanism och dess småstadsideal, samt en diskussion kring frågan om det går att bygga städer i förorten. Med utgångspunkt i amerikanska och brittiska exempel diskuteras vad en nybyggd småstad skulle kunna vara och hur möjligheterna att lyckas med att bygga nya städer ser ut. Slutsatsen blir att det är möjligt,

Establishing a valid cohort of patients with acromegaly by combining the National Patient Register with the Swedish Pituitary Register

Purpose: The aim of this study was to establish a valid national cohort of patients diagnosed with acromegaly by combining data from the general National Patient Register (NPR) and the disease-specific Swedish Pituitary Register (SPR). Methods: Patients ≥ 18 years of age at diagnosis of acromegaly reported from 1991 to 2018 who were registered in the NPR and/or SPR were included. The diagnosis of

Estetiska regler och arkitekturkvalitet

I kapitlet diskuteras sambandet mellan estetiska regler och kvalitet i ett arkitektursammanhang. Utgångspunkt är fallstudier hämtade från den amerikanska stadbyggnadsrörelsen New Urbanism och den teori som jag utvecklade i min avhandling "Seaside, Windsor och Celebration". Viktiga huvudbegrepp är stabil och spontan kvalitet, vilka står för kvalitet som är hög/god tack vare rådande normer, respekti

Navigating Open Polities for Change in Swedish Bilateral Development Cooperation Projects

International development cooperation is undergoing a transformation, driven by the urgent need for more effective, holistic approaches to address enduring global challenges. This thesis explores the paradigmatic shift towards complex adaptive systems (CAS) thinking in Swedish bilateral development cooperation project management, in response to these challenges. This shift mirrors a broader evolut

Evolutionary plant–pollinator responses to anthropogenic land-use change : impacts on ecosystem services

Agricultural intensification at field and landscape scales, including increased use of agrochemicals and loss of semi-natural habitats, is a major driver of insect declines and other community changes. Efforts to understand and mitigate these effects have traditionally focused on ecological responses. At the same time, adaptations to pesticide use and habitat fragmentation in both insects and flow

Computationally efficient direction of arrival estimation using adaptive grid selection

The authors propose a computationally efficient approach to estimate the directions of arrival of far-field sources impinging on a sensor array. The proposed estimator is formed using a sparse reconstruction framework, employing a novel adaptive grid selection technique to reduce the dimensionality of the used dictionary matrix. The method further makes use of a SPICE-inspired dictionary to adapti

Impact of simulated reduced injected dose on the assessment of amyloid PET scans

Purpose: To investigate the impact of reduced injected doses on the quantitative and qualitative assessment of the amyloid PET tracers [18F]flutemetamol and [18F]florbetaben. Methods: Cognitively impaired and unimpaired individuals (N = 250, 36% Aβ-positive) were included and injected with [18F]flutemetamol (N = 175) or [18F]florbetaben (N = 75). PET scans were acquired in list-mode (90–110 min po

Braided Convolutional Self-orthogonal Codes with Double Sliding Window Decoding

In this paper, we investigate a class of braided convolutional codes (BCCs), where the component codes are convolutional self-orthogonal codes (CSOCs), called braided convolutional self-orthogonal codes. Compared to conventional BCCs, the advantages of braided CSOCs include the availability of several low-complexity decoding methods and the relative ease of extending these methods to high rates Mo

Forecasting the Value of Vibration-Based Monitoring Information in Structural Integrity Management

Structural deterioration and increasing load demand are two main factors that compromise the serviceability and functioning of civil constructions. The vastity of the bridge portfolio and the few resources available require maintenance optimization to provide the required user safety. In this context, vibration-based monitoring may provide information about the structural performance and support d

Combined Connectomics, MAPT Gene Expression, and Amyloid Deposition to Explain Regional Tau Deposition in Alzheimer Disease

Objective: We aimed to test whether region-specific factors, including spatial expression patterns of the tau-encoding gene MAPT and regional levels of amyloid positron emission tomography (PET), enhance connectivity-based modeling of the spatial variability in tau-PET deposition in the Alzheimer disease (AD) spectrum. Methods: We included 685 participants (395 amyloid-positive participants within

The analysis of critical success factors for successful kaizen implementation during the COVID-19 pandemic : a textile industry case study

Purpose: The primary objective of this research is to determine critical success factors (CSFs) that enable textile enterprises to effectively implement Kaizen, a Japanese concept of continuous development, particularly during disruptive situations. The study aims to provide insights into how Kaizen is specifically employed within the textile sector and to offer guidance for addressing future cris

Paternal pre-conceptional smoking and semen quality in the adult son

Background: Growing evidence suggests intergenerational effects of paternal pre-conceptional smoking through the germ line, but its specific impact on offspring semen quality remains uncertain because of challenges in isolating paternal exposure from maternal passive smoking or underreporting. Methods: We reran previous analyses estimating differences in semen parameters and testicular size accord

Road Infrastructure Safety Management : Review of National Design Guidelines and Procedures

Som en del av HORIZON EUROPE-projektet AfroSAFE: Säkert system för radikal förbättring av trafiksäkerheten i afrikanska låg- och medelinkomstländer, en översyn av nationella bestämmelser, riktlinjer och procedurer för väginfrastruktursäkerhetshantering (RISM), såväl som vägar. designriktlinjer utfördes i Ghana, Tanzania och Zambia. Information samlades in från relevanta myndigheter och granskningeAs part of the HORIZON EUROPE project AfroSAFE, a review of national regulations, guidelines, and procedures for Road Infrastructure Safety Management (RISM), as well as road design guidelines was carried out in Ghana, Tanzania, and Zambia. Information was collected from relevant authorities and the review had special attention to the safety of vulnerable road users (pedestrians, cyclists, and mot