An early age at first full-term birth is associated with a reduction in the subsequent development of breast cancer among women in the general population. A similar effect has not yet been reported among women who carry an inherited BRCA1 or BRCA2 mutation. We conducted a matched case–control study on 1816 pairs of women with a BRCA1 (n = 1405) or BRCA2 (n = 411) mutation in an attempt to elucidat

Purpose of this paper This paper aims to contribute to the logistics complexity discourse driven at the NOFOMA conference with a novel perspective on complication vs. complexity in studying and managing logistics and supply chains. Design/methodology/approach Research approach is based on description, exploration and analysis of root causes and origins of supply chain complication and complexity.

Brain-derived neurotrophic factor (BDNF) has been shown to promote the survival of cultured fetal mesencephalic dopaminergic neurons of rat and human origin. In the present study, BDNF was tested for its ability to influence neuronal structure of dopaminergic neurons in dissociated cultures of human fetal ventral mesencephalon after 7 days in vitro. Following immunocytochemical staining for tyrosi

Modern office buildings have high energy savings potential and potential for indoor climate improvements. During the nineties many office buildings with glass facades were built, in several cases with double skin glass facades. The advantages of buildings with double skin facades (compared with single skin glazed ones) are considered to be the reduced heating and cooling demand, the increased soun

The homogenization of the Maxwell equations at fixed frequency is addressed in this paper. The bulk (homogenized) electric and magnetic properties of a material with a periodic microstructure are found from the solution of a local problem on the unit cell by suitable averages. The material can be anisotropic, and satisfies a coercivity condition. The exciting field is generated by an incident field fr

Throughout history packages are used to contain, store and transport goods and products. In early days it was a matter of gathering and storing locally, whereas in today’s global enterprises packaging is an important issue in the operational management in networks of functions and/or divisions, often separated geographically around the world. Packaging has become a part of the process of efficient

Abstract: In order to evaluate physical capacity it is neccesary to choose an appropriate method depending on the condition of the subject being tested and on the purpose of testing. A review has been carried out in order to present some of the protocols for evaluating exercise capacity which are in practical use. Twenty different test protocols for evaluating exercise capacity; 12 cycle protocols