The BOADICEA breast cancer (BC) risk assessment model and its associated Web Application v3 (BWA) tool are being extended to incorporate additional genetic and non-genetic BC risk factors. From an online survey through the BOADICEA website and UK, Dutch, French and Swedish national genetic societies, we explored the relationships between the usage frequencies of the BWA and six other common BC ris

Introduction: Roux-en-Y gastric bypass (RYGB) causes more rapid and enhanced absorption of alcohol. RYGB patients have also been reported to use more inpatient care for alcohol-related disease than do patients after other bariatric procedures. The present study was designed to evaluate alcohol consumption level before and after gastric bypass using a sensitive and specific alcohol biomarker. Mater

Galectin-9 consists of two peptide-linked carbohydrate recognition domains (CRDs), but alternative splicing and proteolytic processing can give rise to multiple galectin-9 isoforms. Some of these consist of a single CRD and can exert different functions in cell biology. Here, we explored the role of these galectin-9 isoforms in endothelial cell function and angiogenesis. For this, we compared the

Childhood cancer survivors face risks from a variety of late effects, including cardiac events, second cancers, and late mortality. The aim of the pan-European PanCare Childhood and Adolescent Cancer Survivor Care and Follow-Up Studies (PanCareSurFup) Consortium was to collect data on incidence and risk factors for these late effects among childhood cancer survivors in Europe. This paper describes

The aim of this article is to analyse popular neuroimaging of (dis)able(d) brains as a cultural phenomenon, as well as to explore how there has been, during the last decades, a subtle but important change in the way “normal” brains are depicted in popular science. Popular neuroimaging is introduced and used as an empirical basis to analyse what Fiona Kumari Campbell sees as a critique against able

Ferrofluids based on insulating liquids are intensively studied as a potential substitute of liquid dielectric in high voltage technologies. In this work we focus on the experimental investigation of flow and thermal transport characteristics of a ferrofluid based on transformer oil (Mogul) and iron oxide nanoparticles. The magneto-rheological behavior of the ferrofluid was studied by a rotational

The aim of this study was to investigate hydrogen mobility within innate and demineralized human dentine. Dentine sections from extracted human molars, demineralized or not, were analyzed by combining neutron spectroscopy with thermal analysis. For the thermal analysis of the samples, differential scanning calorimetry and thermal gravimetric analysis, coupled with Fourier transform infrared spectr

A model of (Formula presented.) atmospheric transport in vegetated canopies is tested against measurements of the flow, as well as (Formula presented.) concentrations at the Norunda research station located inside a mixed pine–spruce forest. We present the results of simulations of wind-speed profiles and (Formula presented.) concentrations inside and above the forest canopy with a one-dimensional

The design of buildings using multilayer constructions poses a challenge for fire safety and needs to be understood. Narrow air gaps and cavities are common in many constructions, e.g. ventilated façade systems. In these construction systems flames can enter the cavities and fire can spread on the interior surfaces of the cavities. An experimental program was performed to investigate the influence

An atmospheric pressure aerosol-based wet thin film coating technique called the nFOG is characterized and applied in polymer film coatings. In the nFOG, a fog of droplets is formed by two air-assist atomizers oriented toward each other inside a deposition chamber. The droplets settle gravitationally and deposit on a substrate, forming a wet film. In this study, the continuous deposition mode of t

The article tells the story of the rise and fall of the organic store Yggdrasill in Iceland. That story features humble founders, caring customers, dedicated staff, as well as anonymous investment funds, and it describes the conversion of organics from a niche market to mainstream consumption. Through an ethnographic account of everyday life at the organic store, the article analyzes how intimacy

Alzheimer's disease (AD) is currently incurable, but there is general agreement that a minimally invasive blood biomarker for screening in preclinical stages would be crucial for future therapy. Diagnostic tools for detection of AD are either invasive like cerebrospinal fluid (CSF) biomarkers or expensive such as positron emission tomography (PET) scanning. Here, we determine the secondary structu

The longitudinal study started with children aged up to 4 who had been taken into care because of unacceptable living conditions and deficient parental care. After their initial stay in a children's home, the 26 children in the research group went on to have diverse placement histories throughout their childhood (up to age 18). The children have been divided into 4 subgroups in accordance with the