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Temporal biomarker profiling reveals longitudinal changes in risk of death or myocardial infarction in Non-ST-segment elevation acute coronary syndrome

BACKGROUND: There are conflicting data on whether changes in N-terminal pro-B-type natriuretic peptide (NT-proBNP) and high-sensitivity C-reactive protein (hs-CRP) concentrations between time points (delta NT-proBNP and hs-CRP) are associated with a change in prognosis. METHODS: We measured NT-proBNP and hs-CRP at 3 time points in 1665 patients with non-ST-segment elevation acute coronary syndrome

Predicting the Outcome for Patients in a Heart Transplantation Queue using Deep Learning

Heart transplantations have made it possible to extend the median survival time to 12 years for patients with end-stage heart diseases. This operation is unfortunately limited by the availability of donor organs and patients have to wait on average about 200 days in a waiting list before being operated. This waiting time varies considerably across the patients. In this paper, we studied the outcom

Treatment outcome in early diffuse cutaneous systemic sclerosis : The European Scleroderma Observational Study (ESOS)

Objectives: The rarity of early diffuse cutaneous systemic sclerosis (dcSSc) makes randomised controlled trials very difficult. We aimed to use an observational approach to compare effectiveness of currently used treatment approaches. Methods: This was a prospective, observational cohort study of early dcSSc (within three years of onset of skin thickening). Clinicians selected one of four protocol

The Terms of Ethnoracial Equality : The Swedish Courts' Reading of Ethnic Affiliation, Race and Culture

This article initially accounts for the discussions concerning the notions ‘ethnic origin’ and ‘race’ that have taken place in the Swedish legislative context and places these within a wider European context. Next follows a mapping of the ways in which Swedish courts, in cases of alleged ethnic discrimination, read the notion of ‘ethnic affiliation’ – defined as ‘national or ethnic origin, skin co

Juridik som politik och om behovet av kritik

Texten belyser genom några nedslag i den författningspolitiska utvecklingen hur politiken förskjutits mot juridik och förrätts­ligats i Sverige under de senaste decennierna – något som fram­för allt är en följd av att svensk rätt underställts en transnation­ell konstitution som höjer marknadsaktörers rättigheter samt mänskliga rättigheter över de politiska instansernas besluts­bef

Automatic Gleason grading of H&E stained microscopic prostate images using deep convolutional neural networks

Prostate cancer is the most diagnosed cancer in men. The diagnosis is confirmed by pathologists based on ocular inspection of prostate biopsies in order to classify them according to Gleason score. The main goal of this paper is to automate the classification using convolutional neural networks (CNNs). The introduction of CNNs has broadened the field of pattern recognition. It replaces the classic