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Background: We have previously demonstrated that elevated concentrations of tumour-associated trypsin inhibitor (TATI) in both tumour tissue (t-TATI) and in serum (s-TATI) are associated with a poor prognosis in colorectal cancer patients. It was also found that s-TATI concentrations were lower in patients with rectal cancer compared to patients with colon cancer. In this study, we investigated th

Popular Abstract in English A central requirement in the design of bridge, or any structure, is that they are safe and do not fail unexpectedly. To ensure that such occurrences are acceptably rare involves predicting the various ways in which the bridge can fail and ensuring that provisions are made to prevent or control these potential failure. In other words, the risks associated with failure shEngineering design, in concise terms, is what engineers do using what they know. It is the underlying decision making activity that determines what is to be built and how it should be built. An ever present requirement in engineering design is that the structure should be safe. While historical approaches to safety in design relied on experience and engineering judgment, modern approaches have rat

Childhood cancer five-year survival now exceeds 70-80%. Childhood exposure to radiation is a known thyroid carcinogen; however, data are limited for the evaluation of radiation dose-response at high doses, modifiers of the dose-response relationship and joint effects of radiotherapy and chemotherapy. To address these issues, we pooled two cohort and two nested case-control studies of childhood can

Effects of helix destabilization on lipid membrane interaction, liposome rupture, and bacterial killing was investigated for variants of the antimicrobial peptide GKE21 (GKEFKRIVQRIKDFLRNLVPR), an internal sequence of human cathelicidin LL-37, by ellipsometry, circular dichroism, fluorescence spectroscopy, and bacterial radial diffusion assay. GKE21 displayed moderate helix induction in buffer, wh

Background: The n-3 polyunsaturated fatty acids eicosapentaenoic acid and docosahexaenoic acid, which are present in fish, are protective against myocardial infarction. However, fish also contains methylmercury, which influences the risk of myocardial infarction, possibly by generating oxidative stress. Methylmercury is metabolized by conjugation to glutathione, which facilitates elimination. Glut

Forskningsprogrammet Bisek2 skall bidra med kunskap och andra resultat, som ger stöd till en effektiv avvägning av mobiliteten med bil i relation till andra mål och värden. Denna rapporten behandlar en översikt över latent mobilitet och restriktioner för personer med nedsatt funktionell förmåga. Den identifierar behov av fortsatt forskning inom området.

Background and purpose A considerable number of patients who undergo surgery for spinal stenosis have residual symptoms and inferior function and health-related quality of life after surgery. There have been few studies on factors that may predict outcome. We tried to find predictors of outcome in surgery for spinal stenosis using patient- and imaging-related factors. Patients and methods 109 pati

This article introduces the notion of sustainability objects to label objects that come with a claim to promote a more sustainable mode of living. The purpose is to show that organizations that develop such objects contribute to defining sustainability. A case study of the development of a food waste-based biogas and biofertilizers production facility serves as empirical example of sustainability

Mediterranean diet has been suggested to explain why coronary heart disease mortality is lower in southern than northern Europe. Dietary habits can be revealed by isotope ratio mass spectrometry (IRMS) measurement of carbon (δ(13)C) and nitrogen (δ(15)N) in biological tissues. To study if diet is associated with human plaque stability, atherosclerotic plaques from carotid endarterectomy on 56 pati

Hösten 1943 genomförde Socialstyrelsen rasbiologiska mätningar av mer än hundra svenskar som myndigheten ansåg var ”tattare”, däribland flera barn. Genom att mäta längden på näsor, armar och pannor ville myndigheten få fram ett objektivt sätt att avgöra vilka svenskar som borde kategoriseras på detta sätt. Målet var att skapa särskilda politiska åtgärder mot gruppen, som länge givits skulden för eSince the 16th Century, there has been Travelling families in Sweden, earning their living by itinerant trades such as horse-trading, scrap-metal-dealing and tinplating. The authorities often labelled these families “tattare”. They suffered from severe discrimination, and authorities as well as scientists claimed that they were a threat against society. These claims were often made with a racializ

Abstract in UndeterminedThe present study combines behavioral observations of memory (deferred imitation, DI, after a brief delay of 30 min and after a long delay of 2-3 weeks) and electrophysiological (event-related potentials, ERPs) measures of associative memory, as well as parental reports of non-verbal and verbal communication in sixteen 14-months-old children. Results show that for DI, the c

Remote sensing (RS) time series are an excellent operative source for information about the land surface across several scales and different levels of landscape heterogeneity. Ustin and Gamon (2010) proposed the new concept of "optical types" (OT), meaning "optically distinguishable functional types", as a way to better understand remote sensing signals related to the actual functional behavior of

In Oceania, there is a strong linguistic link between terms for marine resource exploitation and the division of life forms. Aspects of this relationship (especially in Cook Islands and Tonga) are described and discussed in this paper from a cross-cultural perspective. A Polynesian response to the question of why the shark is not an animal shows that modern science, which is a "science of the abst

Particles with functional groups on their surface were immobilized on premade cryogels through covalent bonding to maximize the accessibility of the target molecules to the surface of the particles. The physical properties of the composite cryogel were characterized by SEM, texture analysis and nitrogen adsorption. Different key factors affecting immobilization were also investigated, e.g., recirc

The face of science has changed. Women now feature alongside men at the forefront of many fields, and this is particularly true in evolutionary biology. This special issue celebrates the outstanding achievements and contributions of women in evolutionary biology, by highlighting a sample of their research and accomplishments. In addition to original research contributions, this collection of artic