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Phenotypic characterization and candidate gene analysis of a short kernel and brassinosteroid insensitive mutant from hexaploid oat (Avena sativa)

In an ethyl methanesulfonate oat (Avena sativa) mutant population we have found a mutant with striking differences to the wild-type (WT) cv. Belinda. We phenotyped the mutant and compared it to the WT. The mutant was crossed to the WT and mapping-by-sequencing was performed on a pool of F2 individuals sharing the mutant phenotype, and variants were called. The impacts of the variants on genes p

A Single High-Sensitivity Cardiac Troponin T Strategy for Ruling Out Myocardial Infarction

Background. Ruling out acute myocardial infarction (AMI) in the emergency department (ED) is challenging. Studies have shown that a high-sensitivity cardiac troponin T (hs-cTnT) <5 ng/L or <6 ng/L at presentation (0 h) can be used to rule out AMI. The objective of this study was to identify whether an even higher hs-cTnT threshold can be used for a safe rule out of AMI in the ED. Methods. The deri

Sikh News in India, 1864–1924: Colonial Reports on Vernacular Newspapers of Punjab : Volume Two: Religious Places, Practices, and Relations

Volume 2: Religious Places, Practices, and RelationsThis handbook, divided into four volumes, presents the first English translations of newspaper articles about the Sikhs published in the weekly press reports for Punjab between 1864 and 1924. Covering press material from over 300 newspapers, the book provides insights into the broader landscape of print media in Indian languages and how discussioAfter the Indian Rebellion of 1857, the colonial administration in British India introduced stricter control over Indian publishers and the press printed in various indigenous languages. Newspapers in the Punjab were monitored and scrutinized from 1864 to understand “native opinions” and identify seditious tendencies. The surveillance resulted in extensive weekly press reports that were considered

Sikh News in India, 1864–1924: Colonial Reports on Vernacular Newspapers of Punjab : Volume Three: Migration, Representation, and Reform

Vol. 3: Migration, Representation, and ReformThis handbook, divided into four volumes, presents the first English translations of newspaper articles about the Sikhs published in the weekly press reports for Punjab between 1864 and 1924. Covering press material from over 300 newspapers, the book provides insights into the broader landscape of print media in Indian languages and how discussions on tThis handbook, divided into four volumes, presents the first English translations of newspaper articles about the Sikhs published in the weekly press reports for Punjab between 1864 and 1924. Covering press material from over 300 newspapers, the book provides insights into the broader landscape of print media in Indian languages and how discussions on the Sikhs in the press evolved in response to

Sikh News in India, 1864–1924: Colonial Reports on Vernacular Newspapers of Punjab : Volume Four: Politics of Repression and Reconciliation

Vol. 4: Politics of Repression and ReconciliationThis handbook, divided into four volumes, presents the first English translations of newspaper articles about the Sikhs published in the weekly press reports for Punjab between 1864 and 1924. Covering press material from over 300 newspapers, the book provides insights into the broader landscape of print media in Indian languages and how discussions This handbook, divided into four volumes, presents the first English translations of newspaper articles about the Sikhs published in the weekly press reports for Punjab between 1864 and 1924. Covering press material from over 300 newspapers, the book provides insights into the broader landscape of print media in Indian languages and how discussions on the Sikhs in the press evolved in response to

Maddison-style estimates of the evolution of the world economy : A new 2023 update

This paper surveys the literature on historical national accounting, discusses the importance of relative income benchmarks for, in particular, historical income estimates, and presents an update of long run global economic development with a new version of the Maddison Project Database (MPD). As benchmarks are central to methodologies for global income comparisons over time, and therefore vital t

On-Chip Neural Induction Boosts Neural Stem Cell Commitment : Toward a Pipeline for iPSC-Based Therapies

The clinical translation of induced pluripotent stem cells (iPSCs) holds great potential for personalized therapeutics. However, one of the main obstacles is that the current workflow to generate iPSCs is expensive, time-consuming, and requires standardization. A simplified and cost-effective microfluidic approach is presented for reprogramming fibroblasts into iPSCs and their subsequent different

Round table discussion : the management of idiopathic cubital tunnel syndrome

Idiopathic cubital tunnel syndrome is the second most common neuropathy in the upper limb. Best evidence regarding the surgical management of this condition has evolved from anterior or submuscular transposition as the former reference standard, to in situ simple release. Differences of opinion remain regarding the timing of surgery, type of surgery and adjunctive surgery. Four surgeons with Level

Structural characterisation of α-synuclein-membrane interactions and the resulting aggregation using small angle scattering

The presence of amyloid fibrils is a hallmark of several neurodegenerative diseases. Some amyloidogenic proteins, such as α-synuclein and amyloid β, interact with lipids, and this interaction can strongly favour the formation of amyloid fibrils. In particular the primary nucleation step, i.e. the de novo formation of amyloid fibrils, has been shown to be accelerated by lipids. However, the exact m

HLA-A*23 Is Associated With Lower Odds of Acute Retroviral Syndrome in Human Immunodeficiency Virus Type 1 Infection : A Multicenter Sub-Saharan African Study

The role of human leukocyte antigen (HLA) class I and killer immunoglobulin-like receptor molecules in mediating acute retroviral syndrome (ARS) during human immunodeficiency virus type 1 (HIV-1) infection is unclear. Among 72 sub-Saharan African adults, HLA-A*23 was associated with lower odds of ARS (adjusted odds ratio, 0.10 [95% confidence interval, .01–.48]; P = .009), which warrants further s

Burnout resistance based on the Duration of Heating Phase concept – Literature Review and Roadmap

This study focuses on the fire behavior of structural members considering their response until the end of the fire event. The study reviews and discusses a framework for determining the burnout resistance (B) of structural members through the Duration of the Heating Phase concept (DHP). This framework complements the fire resistance rating (FRR) system by providing a rating that captures the sensi

A harmonized database of European forest simulations under climate change

Process-based forest models combine biological, physical, and chemical process understanding to simulate forest dynamics as an emergent property of the system. As such, they are valuable tools to investigate the effects of climate change on forest ecosystems. Specifically, they allow testing of hypotheses regarding long-term ecosystem dynamics and provide means to assess the impacts of climate sce

High-Quality Solution-Processed Quasi-2D Perovskite for Low-Threshold Lasers

Spin-coated quasi-two-dimensional halide perovskite films, which exhibit superior optoelectronic properties and environmental stability, have recently been extensively studied for lasers. Crystallinity is of great importance for the laser performance. Although some parameters related to the spin-coating process have been studied, the in-depth understanding and effective control of the acceleration

Forced Migrations as a European Heritage and Resource for Enhancing Intercultural Cohesion

Social identity theory argues that conflict between groups diminishes if they discover they have something important in common, and if they can build a new hybrid identity together. With this premise in mind, the article demonstrates how present-day experiences of refugees, displaced ethnic groups, political exiles, foreign-born workers, diasporic populations and other migrants may be incorporated

Softness matters : effects of compression on the behavior of adsorbed microgels at interfaces

Deformable colloids and macromolecules adsorb at interfaces as they decrease the interfacial energy between the two media. The deformability, or softness, of these particles plays a pivotal role in the properties of the interface. In this study, we employ a comprehensive in situ approach, combining neutron reflectometry with molecular dynamics simulations, to thoroughly examine the profound influe

L2 motivation and self regulated learning : An integrated model

Motivation and self-regulated learning (SRL) are interrelated constructs. Motivation can be a precursor, a mediator, and an outcome of SRL. In L2 learning, the interrelatedness of motivation and self-regulation has long been recognized (Dörnyei, 2005). However, a conceptualization of the connections is lacking. This article models the L2 motivation–SRL relationship. Drawing a distinction between p

Enclosure fire dynamics with a cross-laminated timber ceiling

An experimental study of the influence of an exposed combustible ceiling on compartment fire dynamics has been performed. The fire dynamics in compartments with combustible cross-laminated timber ceilings vs non-combustible reinforced concrete ceilings in otherwise identical compartments with three different ventilation factors were investigated. The experimental results are compared against predi