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Selective reporting bias due to discrepancies between registered and published outcomes in osteoarthritis trials

Outcome reporting bias (ORB) occurs when outcomes planned in a study protocol are subsequently not reported or are partially reported. Our aim was to analyze ORB in randomized controlled trials (RCTs) about conservative interventions for osteoarthritis (OA) by comparing registered protocols and published manuscripts, as well as association between study funding type and intervention type, and ORB

https://www.lupop.lu.se/article/selective-reporting-bias-due-discrepancies-between-registered-and-published-outcomes-osteoarthritis - 2025-11-05

Assessing physical performance and physical activity in large population-based aging studies: home-based assessments or visits to the research center?

The current study aims to compare correlations between a range of measures of physical performance and physical activity assessing the same underlying construct in different settings, that is, in a home versus a highly standardized setting of the research center or accelerometer recording. We also evaluated the selective attrition of participants related to these different settings and how selecti

https://www.lupop.lu.se/article/assessing-physical-performance-and-physical-activity-large-population-based-aging-studies-home-based - 2025-11-05

Nationwide comparison of long-term survival and cardiovascular morbidity after acute aortic aneurysm repair in patients with and without type 2 diabetes

Patients with type 2 DM had lower rates of both total and cardiovascular mortality after acute AAA repair than those without DM, whereas rates of cardiovascular events, acute myocardial infarction, and stroke did not differ between groups. This might be explained by putative protective effects of DM on the aortic wall. New publication in Journal of Vascular Surgery

https://www.lupop.lu.se/article/nationwide-comparison-long-term-survival-and-cardiovascular-morbidity-after-acute-aortic-aneurysm - 2025-11-05

Consultation prevalence among children, adolescents and young adults with pain conditions: A description of age‐ and gender differences

Among individuals under the age of 25, a significant proportion consult for pain already in early ages, and they also have high healthcare consultation rates for conditions other than pain. The even higher consultation rates among young females need additional attention, both in the clinic and in research. New publication in European Journal of Pain

https://www.lupop.lu.se/article/consultation-prevalence-among-children-adolescents-and-young-adults-pain-conditions-description-age - 2025-11-05

Completeness of case ascertainment in Swedish hospital‐based stroke registers

Some first‐ever stroke patients, such as those with high early case fatality and those with mild stroke, may go undetected with hospital‐based screening used in clinical stroke registers. This can result in selection bias due to not identifying specific groups of patients including some with high early case fatality and those living in healthcare facilities. New publication in Acta Neurologica Sca

https://www.lupop.lu.se/article/completeness-case-ascertainment-swedish-hospital-based-stroke-registers-0 - 2025-11-05

Functioning and disability from 10 to 16 years after traumatic brain injury

The very small changes over 6 years imply that persons with a TBI can reach and maintain a stable level of functioning many years post‐TBI. Women with a moderate‐to‐severe TBI seem to be more vulnerable and may experience a small decline in some aspects of their functioning related to anxiety, depression, irritability, pain and headache and fatigue. The relatively small sample requires further stu

https://www.lupop.lu.se/article/functioning-and-disability-10-16-years-after-traumatic-brain-injury - 2025-11-05

Understanding User Involvement in Research in Aging and Health

User involvement in research is advocated as an avenue for efficient societal developments. In this article, we identify potentials, problems, and challenges related to research on aging and health, and identify and illustrate research priorities using an evolving research program as an example. Involving user representatives in the development phase, the UserAge program engages researchers at fou

https://www.lupop.lu.se/article/understanding-user-involvement-research-aging-and-health - 2025-11-05

Reflections on modern methods: linkage error bias

Linked data are increasingly being used for epidemiological research, to enhance primary research, and in planning, monitoring and evaluating public policy and services. Linkage error (missed links between records that relate to the same person or false links between unrelated records) can manifest in many ways: as missing data, measurement error and misclassification, unrepresentative sampling, o

https://www.lupop.lu.se/article/reflections-modern-methods-linkage-error-bias - 2025-11-05

Twin Family Registries Worldwide: An Important Resource for Scientific Research

Much progress has been made in twin research since our last special issue on twin registries (Hur, Y.-M., & Craig, J. M. (2013). Twin Research and Human Genetics, 16, 1-12.). This special issue provides an update on the state of twin family registries around the world. This issue includes 61 papers on twin family registries from 25 countries, of which 3 describe consortia based on collaborations o

https://www.lupop.lu.se/article/twin-family-registries-worldwide-important-resource-scientific-research - 2025-11-05

Establishing a National Registry for Hand Surgery

Hand surgery leadership in the United States must identify and define what quality care means for its patients. To achieve this, the surgical team needs a standardized framework to track and improve quality. This is necessary not only in our value-based health care system but also in light of considerable provider variation in the management of common hand conditions and the ongoing need for evide

https://www.lupop.lu.se/article/establishing-national-registry-hand-surgery - 2025-11-05

Well-Being and Working Conditions of Teachers in Sweden

n Sweden, teachers are subject to high turnover, unfavorable working conditions, and high incidence of stress-related disorders. The aim of the present study was to (a) assess teachers’ perceptions of work-related health and working conditions, (b) examine the relationship among sev- eral key characteristics in teachers’ work environment, and (c) examine the importance for well-being of job satisf

https://www.lupop.lu.se/article/well-being-and-working-conditions-teachers-sweden - 2025-11-05

Understanding the complexity of socioeconomic disparities in type 2 diabetes risk: a study of 4.3 million people in Sweden

Investigating demographic and socioeconomic factors as intersecting rather than as separate dimensions may improve our understanding of the heterogeneous distribution of type 2 diabetes in the population. However, this complexity has scarcely been investigated and we still do not know the accuracy of these factors for predicting type 2 diabetes. Improved understanding of the demographic and socioe

https://www.lupop.lu.se/article/understanding-complexity-socioeconomic-disparities-type-2-diabetes-risk-study-43-million-people - 2025-11-05

Lifestyle and cancer incidence and mortality risk depending on family history of cancer in two prospective cohorts

The extent to which a favorable lifestyle may lower cancer risk in subjects with a family history of cancer is unknown. We conducted a prospective study in two Swedish cohorts, the Malmö Diet and Cancer Study (MDCS; n = 25,604) and the Malmö Preventive Project (MPP; n = 16,216). The association between a favorable lifestyle (based on nonsmoking, normal weight, absence of excessive drinking, regula

https://www.lupop.lu.se/article/lifestyle-and-cancer-incidence-and-mortality-risk-depending-family-history-cancer-two-prospective - 2025-11-05

Mental health and experience of being bullied in 12‐year‐old children with overweight and obesity

The aim was to study the association between weight, mental health and experience of being bullied in 12‐year‐old children. Additional aim was to investigate the impact of childhood psychosocial risk factors for overweight and obesity at age 12. New publication in Acta Paediatrica

https://www.lupop.lu.se/article/mental-health-and-experience-being-bullied-12-year-old-children-overweight-and-obesity - 2025-11-05

Discrepancies in the Registries of Diet vs Drug Trials

ClinicalTrials.gov was established in 2000 in response to the Food and Drug Administration Modernization Act of 1997, which called for registration of trials of investigational new drugs for serious diseases. Subsequently, the scope of ClinicalTrials.gov expanded to all interventional studies, including diet trials. Presently, prospective trial registration is required by the National Institutes o

https://www.lupop.lu.se/article/discrepancies-registries-diet-vs-drug-trials - 2025-11-05

Use of National Joint Registries to Evaluate a New Knee Arthroplasty Design

The introduction of new technology in joint replacement surgery requires close monitoring to identify early successes and failures. This monitoring can be effectively performed through the analysis of registry data and radiostereometric analysis studies. This study examined the revision rates of a contemporary knee system for total knee arthroplasty (TKA) using National Joint Replacement Registrie

https://www.lupop.lu.se/article/use-national-joint-registries-evaluate-new-knee-arthroplasty-design - 2025-11-05