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Locally weighted least squares kernel regression and statistical evaluation of LIDAR measurements
The LIDAR technique is an efficient tool in monitoring the distribution of atmospheric species of importance. We study the concentration of atmospheric atomic mercury in an Italian geothermal field and discuss the possibility of using recent results from local polynomial kernel regression theory for the evaluation of the derivative of the DIAL curve. A MISE-optimal bandwidth selector, which takes
Diltiazem protects human NT-2 neurons against excitotoxic damage in a model of simulated ischemia
in vitro models are often used to investigate pathophysiological mechanisms of brain cell injury as they occur for instance during cerebral ischemia. To analyze the efficacy of potential neuroprotective compounds, cell physiological experiments were performed in a recently improved culture system of human model neurons. The postmitotic neurons were generated from the human NT-2 teratocarcinoma cel
Polymerase chain reaction-based identification of Plasmodium (Huffia) elongatum, with remarks on species identity of haemosporidian lineages deposited in GenBank
Numerous lineages of avian malaria parasites of the genus Plasmodium have been deposited in GenBank. However, only 11 morphospecies of Plasmodium have been linked to these lineages. Such linking is important because it provides opportunities to combine the existing knowledge of traditional parasitology with novel genetic information of these parasites obtained by molecular techniques. This study l
Assessing educational priorities in genetics for general practitioners and specialists in five countries: factor structure of the Genetic-Educational Priorities (Gen-EP) scale
Purpose: A scale assessing primary care physicians' priorities for genetic education (The Gen-EP scale) was developed and tested in five European countries. The objective of this study was to determine its factor structure, to test scaling assumptions and to determine internal consistency. Methods: The sample consisted of 3686 practitioners (general practitioners, gyneco-obstetricians, pediatricia
Roentgen single-plane photogrammetric analysis (RSPA.) A new approach to the study of musculoskeletal movement.
We present a new approach for the accurate reconstruction of three-dimensional skeletal positions using roentgen single-plane photogrammetric analysis (RSPA). This technique uses a minimum of three markers embedded in each segment which allow continuous, real-time, internal skeletal movement to be measured from single-plane images, provided that the precise distance between the markers is known. A
Experimental determination of beam quality factors, k(Q), for two types of Farmer chamber in a 10 MV photon and a 175 MeV proton beam.
Ecology of long-distance movements: migration and orientation performance
Abstract is not available
Macroporous polyacrylamide monolithic gels with immobilized metal affinity ligands: The effect of porous structure and ligand coupling chemistry on protein binding
Macroporous polyacrylamide gels (MPAAG) with iminodiacetic acid (IDA) functionality were prepared by (i) chemical modification of polyacrylamide gel, (ii) co-polymerization of acrylamide with allyl glycidyl ether (AGE) and N,N' metylene-bis(acrylamide) (MBAAm) followed by coupling IDA ligand or (iii) by copolymerization of acrylamide and MBAAm with functional monomer carrying IDA-functionality (1-
Serotonergic agonists behave as partial agonists at the dopamine D2 receptor
RAT dopamine D2short receptors expressed in CHO cells were characterized by activation of [35S]GTPgammaS binding. There were no significant differences between the maximal effects seen in activation of [35S]GTPgammaS binding caused by dopaminergic agonists, but the effects of 5-HT, 8OH-DPAT and 5-methoxytryptamine amounted to 47 +/- 7%, 43 +/- 5% and 70 +/- 7% of the dopamine effect, respectively.
Reflection photoelasticity: a new method for studies of clinical mechanics in prosthetic dentistry
Objectives. This research was conducted to demonstrate the effectiveness of reflective photoelasticity as an in vivo technique for monitoring the strain/stress distribution in prosthetic devices during function. Methods. Seven subjects were selected for this study and divided into three groups according to the design of the prostheses. The buccal surfaces of the experimental prostheses were coated
Predictors of natal dispersal in great reed warblers: results from small and large census areas
For most species, it is currently not known whether individual characteristics and population parameters affecting dispersal distances within the local population are also affecting dispersal of individuals emigrating longer distances. We evaluated this in the great reed warbler Acrocephalus arundinaceus by analysing data of natal dispersal distances within (1) the local hatching area in southern
Coordinated patterns of cytochrome bd and lactate dehydrogenase expression in Bacillus subtilis
A variety of pathways for electron and carbon flow in the soil bacterium Bacillus subtilis are differentially expressed depending on whether oxygen is present in the cell environment. This study characterizes the regulation of the respiratory oxidase cytochrome bd and the NADH-linked fermentative lactate dehydrogenase, (LDH). Transcription of the cydABCD operon, encoding cytochrome bd, is highly r
Lipopolysaccharide (LPS) inhalation in healthy subjects increases neutrophils, lymphocytes and fibronectin levels in bronchoalveolar lavage fluid
Bacterial endotoxin has been suggested as responsible for the development of subjective symptoms and transient or chronic lung function impairment seen after exposure to organic dusts in cotton mills, poultry houses, swine confinement buildings and saw mills. Animal experiments have demonstrated bronchoalveolar neutrophilia being the most prominent cell response in animals following bacterial lipo
Limited diversity of the protein D gene (hpd) among encapsulated and nonencapsulated Haemophilus influenzae strains
Protein D is a surface-exposed lipoprotein of the gram-negative bacterium Haemophilus influenzae with affinity for human immunoglobulin D myeloma protein. The gene encoding protein D (hpd) in a serotype b strain of H. influenzae was cloned. Escherichia coli carrying the hpd gene bound human myeloma immunoglobulin D. Nucleotide sequence analysis identified an 1,092-bp open reading frame that was mo
Type 1 diabetes-related autoantibodies are rare in Alaska native populations.
OBJECTIVES: When clinical data were initially gathered from the Alaskan Eskimos in the 1950's, diabetes mellitus was noted to be quite rare. The prevalence of diabetes has increased significantly since that time, with rates of 10% reported recently in some Alaska native populations. Our goal was to understand the pathogenesis of diabetes among these groups, with the hypothesis that Alaskan Eskimos
Nuclear and chloroplast microsatellites reveal extreme population differentiation and limited gene flow in the Aegean endemic Brassica cretica (Brassicaceae)
Nuclear and chloroplast microsatellite markers were used to study population structure and gene flow among seven Cretan populations of the Aegean endemic plant species Brassica cretica (Brassicaceae). Both nuclear and chloroplast markers revealed exceptionally high levels of population differentiation (overall FST = 0.628 and 1.000, respectively) and relatively little within-population diversity (
A novel mechanism of action of the fumagillin analog, TNP-470, in the B16F10 murine melanoma cell line
TNP-470, a semisynthetic derivative of fumagillin, is an acknowledged angiogenesis inhibitor, presently undergoing clinical trials. It exerts an anti-proliferative effect directed against endothelial cells. This effect is known to be based on cell cycle inhibition effected by the p53/p21 pathway. We observed short-term toxicity of TNP-470 in the B16F10 murine melanoma cell line in vitro and invest
Does hormone therapy increase allergic reactions and upper gastrointestinal problems?; Results from a population-based study of Swedish woman. The women's health in the Lund area (WHILA) study.
Objectives: To delineate the use of various drugs particularly pertaining to allergy and upper gastrointestinal problems in relation to hormone status in middle aged women. Methods: An analysis from a population-based study on women born between 1935 and 1945 and lived in the Lund area southern Sweden. Of 10766 women, 6917 provided complete data sets; in turn 5673 were assessed for the use of medi
Fuzzy traceability: A process simulation derived extension of the traceability concept in continuous food processing
Abstract in Undetermined Liquid food production often involves continuous processing. This leads to problems in traceability systems due to mixing zones and therefore indistinct batch identities causing difficulties with regard to withdrawals or recalls. This article outlines the possible use of the concept of dynamic simulation to improve the handling of batch identities in continuous production