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Autoimmune hepatitis (AH) and primary biliary cirrhosis (PBC) are autoimmune diseases (AIDs) targeting cellular components of the liver. Being rare diseases, limited data are available about familial risks among these AIDs (concordant) or between them and other AIDs (discordant). We aimed to carry out an unbiased study on these AIDs based on medically diagnosed patients. Read more at Familial asso

https://www.lupop.lu.se/article/familial-associations-between-autoimmune-hepatitis-and-primary-biliary-cholangitis-and-other - 2025-12-13

The study population included a random sample of 2656 men (45.7%) and 3159 (54.3%) women from the longitudinal national studies' "Good Aging in Skåne" (GÅS) and SNAC-B, both part of the Swedish National Study on Aging and Care (SNAC). Data on Neugartens Life Satisfaction Index-A (LSI-A), medical history, activities of daily life (ADL) and socio-demographics were collected through structured interv

https://www.lupop.lu.se/article/life-satisfaction-index-lsi-normative-data-general-swedish-population-aged-60-93-years - 2025-12-13

Öppna utlysningar: Bidrag till kliniska studier inom behandlingsforskning - skissansökan / Bidrag till investering i befintlig forskningsinfrastruktur / Internationell postdok inom medicin och hälsa (vårens utlysning) / Internationell postdok inom naturvetenskap och teknikvetenskap (vårens utlysning) / Internationell postdok inom humaniora och samhällsvetenskap inklusive utbildningsvetenskap (våre

https://www.lupop.lu.se/article/vrs-utlysningsar-2021-ar-nu-igang - 2025-12-13

It is now much easier for researchers to make use of SND’s web services. The first step is an improved service for the submission of research data for description and reuse. The next step will simplify the process of ordering data from SND. Read more here.

https://www.lupop.lu.se/article/snd-launches-improved-web-service-researchers - 2025-12-13

Att forskningsresultat ska kunna upprepas är en av vetenskapens grundläggande principer. Ändå visar flera genomgångar av vetenskapliga studier att det inte ser ut så. Kritiker pekar på flera orsaker och nu vill forskare minska fokus på publiceringshetsen för att minska felaktigheter. Hör mer på https://sverigesradio.se/artikel/7647634.

https://www.lupop.lu.se/article/problem-i-forskarvarlden-manga-forskningsresultat-kan-inte-upprepas - 2025-12-13

Traumatic brain injury (TBI) is a major cause of disabilities and mortality worldwide, with higher prevalence in offender populations than in the general population. Previous research has strongly advocated increased awareness of TBI in offender populations. The aim of this study was to explore the prevalence and characteristics of TBI, and to investigate associations and interactions between TBI,

https://www.lupop.lu.se/article/exploring-traumatic-brain-injuries-and-aggressive-antisocial-behaviors-young-male-violent-offenders - 2025-12-13

The Kingdom of Crystal, an area in southern Sweden famous for its many glassworks, is historically heavily burdened by pollution from this industry. Glass crust containing cadmium (Cd), lead (Pb), and arsenic (As) has been deposited around the area and used as filling. The purpose of this study was to monitor whether the high levels of metals in the contaminated soil were reflected in blood and ur

https://www.lupop.lu.se/article/cadmium-and-lead-levels-blood-and-arsenic-levels-urine-among-schoolchildren-living-contaminated - 2025-12-13

It has been suggested that high intake of added sugar and sugar-sweetened beverages (SSBs) increase the level of circulating inflammatory proteins and that chronic inflammation plays a role in type 2 diabetes (T2D) development. We aim to examine how added sugar and SSB intake associate with 136 measured plasma proteins and C-reactive protein (CRP) in the Malmö Diet and Cancer–Cardiovascular Cohort

https://www.lupop.lu.se/article/identification-inflammatory-and-disease-associated-plasma-proteins-associate-intake-added-sugar-and - 2025-12-13

With case record review, the outcomes and malignancy development in a cohort of 195 patients with AAV [granulomatosis with polyangiitis (GPA), microscopic polyangiitis, and eosinophilic GPA] diagnosed between 1997 and 2010 were assessed. The patients were followed until death or December 31, 2015. The age- and sex-standardized incidence ratios (SIR) were estimated using the Swedish population data

https://www.lupop.lu.se/article/malignancies-patients-antineutrophil-cytoplasmic-antibody-associated-vasculitis-population-based - 2025-12-13

Data were obtained from the prospective, longitudinal, population‐based Children of Western Sweden cohort, which focused on children born in 2003. The parents answered questionnaires at six months and one, four, eight and 12 years of age. Personal identity numbers linked 3634 children to the Swedish Prescribed Drug Register (SPDR) and the National Patient Register (NPR). Read more at Parental ques

https://www.lupop.lu.se/article/parental-questionnaires-provided-reliable-data-childhood-asthma-compared-national-registers - 2025-12-13

Quality in medical research has recently been criticized for being low, especially in observational research. Methodology is increasingly difficult, but collaboration between clinical researchers and biostatisticians may improve research and reporting quality. The aim of this study is to quantify the value of a biostatistician in the team of authors. Read more at Is reporting quality in medical pu

https://www.lupop.lu.se/article/reporting-quality-medical-publications-associated-biostatisticians-co-authors-registered-report - 2025-12-13

Countries with the highest burden of maternal and newborn deaths and stillbirths often have little information on these deaths. Since over 81% of births worldwide now occur in facilities, using routine facility data could reduce this data gap. We assessed the availability, quality, and utility of routine labour and delivery ward register data in five hospitals in Bangladesh, Nepal, and Tanzania. T

https://www.lupop.lu.se/article/labour-and-delivery-ward-register-data-availability-quality-and-utility-every-newborn-birth - 2025-12-13

The authors assessed the effect of incorporating the timing of cancer diagnosis events into the assessment of familial risks of breast cancer in first‐degree and second‐degree relatives in a nationwide cohort study of 5,099,172 women (follow‐up was between 1958‐2015). Family history was assessed using 3 approaches: 1) as a static variable (ever having a relative with breast cancer); 2) as accumula

https://www.lupop.lu.se/article/familial-risk-breast-cancer-dynamic-accumulative-and-static-definitions-family-history - 2025-12-13

Ulnar nerve entrapment at the elbow (UNE) is overrepresented in patients with diabetes, but the outcome of surgery is unknown. We aimed to evaluate patient-reported outcome in patients with and without diabetes, and to assess potential sex differences and compare surgical treatment methods. Data on patients operated for UNE (2010-2016, n = 1354) from the Swedish National Registry for Hand Surgery

https://www.lupop.lu.se/article/ulnar-nerve-entrapment-diabetes-patient-reported-outcome-after-surgery-national-quality-registries - 2025-12-13

Nyhetsbrev från Svensk nationell datatjänst juni 2020. Läs mer här.

https://www.lupop.lu.se/article/snd-natverksnytt-0 - 2025-12-13

The recommendations in the document are aimed at helping policymakers and funders to maximise timely, quality data sharing and appropriate responses in future health emergencies. The Research Data Alliance (RDA) COVID-19 Working Group members bring various, global expertise to develop a body of work that comprises how data from multiple disciplines inform response to a pandemic combined with guide

https://www.lupop.lu.se/article/rda-covid-19-recommendations-and-guidelines-data-sharing - 2025-12-13

In this review, we explain statistical concepts targeted towards patients, clinicians and healthcare professionals that summarize cancer patient survival under the assumption that other causes of death exist. Specifically, we explain the appropriate use, interpretation and assumptions behind statistical methods for competing risks, loss in life expectancy due to cancer and conditional survival. Re

https://www.lupop.lu.se/article/cancer-survival-statistics-patients-and-healthcare-professionals-tutorial-real-world-data-analysis - 2025-12-13

Estimates from Mendelian randomization studies of unrelated individuals can be biased due to uncontrolled confounding from familial effects. Here we describe methods for within-family Mendelian randomization analyses and use simulation studies to show that family-based analyses can reduce such biases. Read more here.

https://www.lupop.lu.se/article/avoiding-dynastic-assortative-mating-and-population-stratification-biases-mendelian-randomization - 2025-12-13

McMaster GRADE Centre researchers developed ‘health outcome descriptors’ for standardizing descriptions of health outcomes and overcoming these problems to support the European Commission Initiative on Breast Cancer (ECIBC) Guideline Development Group (GDG). We aimed to determine which aspects of the development, content, and use of health outcome descriptors were valuable to guideline developers.

https://www.lupop.lu.se/article/development-and-use-health-outcome-descriptors-guideline-development-case-study - 2025-12-13

Objectives: To investigate use of data from a clinical quality registry for cardiac rehabilitation in Denmark, considering the extent to which data are used for local quality improvement and what facilitates the use of these data, with a particular focus on whether there are differences between frontline staff and managers. Read more here.

https://www.lupop.lu.se/article/facilitators-using-data-quality-registry-local-quality-improvement-work-cross-sectional-survey-0 - 2025-12-13