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Synaptic dopamine release from embryonic nigral transplants has been monitored in the striatum of a patient with Parkinson's disease using [11C]-raclopride positron emission tomography to measure dopamine D2 receptor occupancy by the endogenous transmitter. In this patient, who had received a transplant in the right putamen 10 years earlier, grafts had restored both basal and drug-induced dopamine
The use of fossil energy is one of the major environmental problems associated with tourism and travel. Consequently, the need to limit fossil energy use has been highlighted as a precondition for achieving sustainable tourism development. However, tourism is also one of the most important sectors of the world economy, and fears have thus been expressed by the tourist industry and its organisation
Global problems such as atmospheric change, acid rain, and water pollution in surface and subsurface environments dominate discussions of world environmental problems. In this thesis the roles of hydrologic processes and hydrogeochemical processes are investigated through development, modification, and application of models for addressing point and non-point source contamination of water. The move
Modifications to a model describing swash motion based on solutions to the non-linear shallow water equations were made to account for interaction between up-rush and back-wash at the still water shoreline and within the swash zone. Inputs to the model are wave heights and arrival times at the still water shoreline. The model was tested against wave groups representing idealized vessel-generated w
On Pehr Löfling's expedition to Venezuela 1754-1756
The purpose of this Phase II study was to evaluate if alum-formulated human recombinant GAD65 is safe and does not compromise beta cell function. The study was conducted as a randomized, double blind, placebo-controlled, dose-escalation clinical trial in a total of 47 Latent Autoimmune Diabetes in Adults (LADA) patients who received either placebo or 4, 20, 100, or 500 μg Diamyd subcutaneously at
Movement data are analyzed to elucidate principles of articulator coordination. Procedures for tracking articulator gestures from x-ray motion films, and results obtained from Swedish and Bulgarian work are reported in Wood [J. Phon. 19, 281–292 (1991), Proc. 3rd Congress I.C.P.L.A., 191-200, Helsinki (1994), Proc. 13th I.C.Ph.Sc., Vol. 1, 392–395, Stockholm (1995), J. Phon. (in press)]. Coarticul
Mobile phones become smaller but include more advanced functions for every new generation. This paradox is possible since reduced transistor size and increased integration of digital building blocks free space for new functions. Unfortunately, not all components are easily integrated or scaled, such as the antenna, since its performance is dependent on the size. Shrinking mobile phone size results
To characterize prostate-specific antigen (PSA) produced by cancer cells, different isoforms of PSA secreted by the human prostate cancer cells, LNCaP, were purified. LNCaP-PSA production was induced by synthetic androgen, R1881. LNCaP-PSA was separated into four pools. The molecular mass of LNCaP-PSA isoforms in these pools was 34 kDa under reducing conditions and 29 kDa under nonreducing conditi
The twin hook has been developed as an alternative to the conventional lag screw to be combined with a barrelled side-plate in the treatment of trochanteric hip fractures. With two oppositely directed apical hooks introduced into the subchondral bone of the femoral head, the twin hook provides different stabilising properties to the lag screw. The femoral head purchase of the twin hook and the lag
In this paper we discuss the possibility of a general paradigm for cell-biomaterial and cell-nanoparticle interactions. The basis of the paradigm is that the nature of the biomaterial or nanoparticle surface is not the important parameter, but rather the nature of the outermost layer of adsorbed proteins as well as long-lived misfolded proteins shed from the surfaces. If the adsorbed protein is ir
The purpose of this report is to design a thickness controller fo a hot rolling mill. The thickness control problem is difficult and small improvements make large savings possible. It is therefore relevant to use advanced control strategiesfor controlling the plate thickness. In the report a short introduction to the thickness control problem, and a description ofhow thickness control is done toda
Formaldehyde (CH2O) is an important intermediate species in combustion processes and it can through laser-induced fluorescence measurements be used for instantaneous flame front detection. The present study has focussed on the use of the third harmonic of a Nd:YAG laser at 355 nm as excitation wavelength for formaldehyde, and different dimethyl ether (C2H6O) flames were used as sources of formalde
Conclusions. Thorough otomicroscopical examination of the tympanic membrane in acute otitis media (AOM) might distinguish AOM episodes caused by different bacteria. It thus might be a way to select appropriate treatment for each patient without raising the number of dangerous complications. Objectives. The aim of this study was to see if it might be possible to predict the causative bacterium by j
