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Objectives: To quantify the influence of lifestyle factors on tumour necrosis factor inhibitor (TNFi) treatment response, in axial spondyloarthritis (axSpA). Methods: Data on biologics-naïve adults with axSpA were captured from European rheumatology registries. Information on lifestyle factors (smoking, overweight/obesity, and/or alcohol consumption) were identified ± 30 days of commencing their f

The main subject of this thesis is the proof of the Prime Number Theorem. It revolves around the Riemann zeta function, whose continuation to a meromorphic function in the complex plane is discussed. We employ auxiliary functions, including the Chebyshev function, to simplify the proof of the theorem to showing an equivalent statement.

OBJECTIVES: Penicillin V (PcV) is considered the first-line treatment for community-acquired pneumonia in Scandinavian countries, although data supporting this recommendation are scarce. Thus, this study aimed to compare PcV and amoxicillin regarding the risk of treatment failures in children aged >5 years and adults treated for pneumonia in primary care.METHODS: In this retrospective study of hea

The investigation of carbon monoxide (CO) adsorption on the unreconstructed Ir(100)-(1 × 1) surface under ultra-high vacuum (UHV) conditions is studied with scanning tunneling microscopy (STM), low-energy electron diffraction (LEED), and high-resolution core-level spectroscopy (HRCLS). At a low coverage of 0.5 ML (monolayer), CO molecules adopt a previously documented c(2 × 2) structure, having CO

A novel approach combining 3D printing, phase inversion, and microwave plasma-enhanced chemical vapor deposition is presented. This technique enables the creation of carbon-based electrodes with precise micro- and nanoscale control, offering potential for sustainable and high-performance wastewater treatment applications. The synthesized 3D carbon scaffolds, enriched with B,N-doped carbon nanostru

Over the last century, district heating (DH) has only achieved global market shares of around 10 %. To reach its potential market shares of 25–50 % in Europe by 2050, growth must drastically accelerate. But deployment of DH is hindered by barriers, potentially slowing this fast-paced transition of the heat system. In this paper, we identify barriers to the deployment of DH through manual and GPT-a

A NNW-trending mafic dyke from the central-western Bastar craton yields a U[sbnd]Pb ID-TIMS baddeleyite age of 1944 ± 6 Ma. By correlating additional dykes with similar trend and geochemical characteristics, we identify a previously unrecognized dyke swarm, named herein the Pakhanjore swarm. Geochemical evidence suggests that the studied rocks are derived from partial melting of a spinel-rich, sha

The recognition of amine groups by ninhydrin, along with a simple mathematical algorithm, showed that di- and tripeptides derived from dietary protein are the major end products of protein digestion entering the blood postprandially. There are thousands of oligopeptides appearing in the gut during protein digestion. However, the presented study on a pig model clearly shows that peptides longer tha

Syftet med studien är att studera hur svensk domstol resonerar gällande partnervåld i vårdnadstvister via tematisk analys. Studien utgår från ett genusrättsvetenskapligt förhållningssätt och försöker därmed förklara studiens resultat enligt genusrättsvetenskapen och tidigare genusforskning. Studiens empiriska material består av slumpmässigt utvalda domar gällande vårdnadstvister som präglas av par

Stabell and Fjeldstad (1998) proposed three value configurations; the value shop, the value chain and the value network based on Thompson’s (1967) three technologies as a typology. However, that Thompson’s technologies constitute a typology has been criticized (cf Barbini and Neri, 2017). Also, research has highlighted increased shifts in value configurations and hybrid forms. Thus, the question a

Artificial intelligence (AI) and machine learning (ML) are rapidly permeating nearly every aspect of modern life, frompersonal devices and autonomous systems to industrial automation and environmental monitoring. The growing demandfor intelligence at the network edge is reshaping how computing hardware is conceived and built. Edge AI platforms areexpected to deliver high throughput within tight en

The impact on prognosis of neutrophil infiltration in the microenvironment of ovarian cancer remains to be elucidated. In this study, we analyzed the association between neutrophil infiltration in peritoneal metastasis and prognosis. Furthermore, we analyzed the correlation between neutrophil infiltration in peritoneal metastasis and the number of peripheral blood neutrophils, the degree of neutro

There is an urgent need for accurate and validated methods to measure plasma phosphorylated tau (p-Tau) biomarkers in Alzheimer’s disease (AD). In this study, we compared the performance of new commercially available plasma p-Tau217 assay developed by ALZpath to other established p-Tau assays in an autopsy-confirmed sample. We included 72 participants from the Arizona Study of Aging and Neurodegen

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder marked by β-amyloid (βA) accumulation, neuroinflammation, excessive synaptic pruning, and cognitive decline. Despite extensive research, effective treatments remain elusive. Here, we identify potassium channel-interacting protein 3 (KChIP3) as a key driver of AD pathology using the 5XFAD mouse model. KChIP3 levels were significan

Resource provisioning for applications hosted in the cloud is a difficult task due to inherent performance variability in the infrastructure. Control theory has proven to be an efficient tool to increase the predictability of cloud applications. However, a prerequisite for a successful control design is an adequate model of the involved dynamics. In this paper we focus on modeling of controlled se

We study the problems of computing the Voronoi diagram and a triangulation of a set of n2 points with O(log⁡n)-bit coordinates in the Euclidean plane in a substantially sublinear in n number of rounds in the congested clique model with n nodes. First, we observe that if the points are uniformly at random distributed in a unit square then their Voronoi diagram within the square can be computed in O

Arabinoxylan (AX) with varying arabinose to xylose (A/X) ratios of 0.85, 0.57 and 0.39 was extracted from wheat bran, and the conformations of the AX polysaccharides dispersed in water were investigated using small-angle X-ray scattering. The persistence length (Lp) and the conformation statistics (expressed by the Flory exponent v or the mass fractal) of the AX varied with their A/X ratios. The L

In this study we investigate risk management trade-offs by evaluating how key persons at workplaces with a potential for exposure to hexavalent chromium (Cr(VI)) reason about what is practically possible in terms of exposure reduction. While the included companies (N = 14) represented different types of processes and work-tasks, interviewees all identified that many types of hazards compete for at