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Background: The delineation of intraprostatic lesions is vital for correct delivery of focal radiotherapy boost in patients with prostate cancer (PC). Errors in the delineation could translate into reduced tumour control and potentially increase the side effects. The purpose of this study is to compare PET-based delineation methods with histopathology. Materials and methods: The study population c

The Covid-19 pandemic sparked unprecedented political responses dramatically affecting societies, markets, and the lives of individuals. Under great uncertainty and turbulent conditions, governments adopted far-reaching political interventions to curb the pandemic. These interventions might therefore be expected to challenge key ideas underpinning liberal democracy. We analyze and compare how the

A search for the nonresonant production of Higgs boson pairs in the Formula Presented channel is performed using Formula Presented of proton-proton collisions at a center-of-mass energy of 13 TeV recorded by the ATLAS detector at the CERN Large Hadron Collider. The analysis strategy is optimized to probe anomalous values of the Higgs boson self-coupling modifier Formula Presented and of the quarti

A search is performed for localized excesses in the low-mass dijet invariant mass distribution, targeting a hypothetical new particle decaying into two jets and produced in association with either a high transverse momentum photon or a jet. The search uses the full Run 2 data sample from LHC proton-proton collisions collected by the ATLAS experiment at a center-of-mass energy of 13 TeV during 2015

The ALICE experiment was proposed in 1993, to study strongly-interacting matter at extreme energy densities and temperatures. This proposal entailed a comprehensive investigation of nuclear collisions at the LHC. Its physics programme initially focused on the determination of the properties of the quark–gluon plasma (QGP), a deconfined state of quarks and gluons, created in such collisions. The AL

Breast cancer is the most frequently diagnosed cancer in females globally. However, we know relatively little about trends in males. This study describes United Kingdom (UK) secular trends in breast cancer from 2000 to 2021 for both sexes. We describe a population-based cohort study using UK primary care Clinical Practice Research Datalink (CPRD) GOLD and Aurum databases. There were 5,848,436 elig

We report the discovery and characterization of a small planet, TOI-1408 c, on a 2.2 day orbit located interior to a previously known hot Jupiter, TOI-1408 b (P = 4.42 days, M = 1.86 ± 0.02 M Jup, R = 2.4 ± 0.5 R Jup) that exhibits grazing transits. The two planets are near 2:1 period commensurability, resulting in significant transit timing variations (TTVs) for both planets and transit duration

Decays of Ξb− and Ωb− baryons to Λc+h−h′− final states, with h−h′− being π−π−, K−π− and K−K− meson pairs, are searched for using data collected with the LHCb detector. The data sample studied corresponds to an integrated luminosity of 8.7 fb−1 of pp collisions collected at centre-of-mass energies s = 7, 8 and 13 TeV. The products of the relative branching fractions and fragmentation fractions for

This essay examines the Bavarian physician, mining engineer, and Catholic romantic philosopher Franz von Baader's (1765-1841) enigmatic claim that we think because we are thought with the help of the moral theologian Servain Pinckaers OP (1925-2008) and the psychologist Mihaly Csikszentmihalyi (1934-2021). Using Pinckaers' idea of 'fontal knowledge' and Csikszentmihalyi's notion of flow, I interprThis essay examines the Bavarian physician, mining engineer, and Catholic romantic philosopher Franz von Baader's (1765-1841) enigmatic claim that we think because we are thought with the help of the moral theologian Servain Pinckaers OP (1925-2008) and the psychologist Mihaly Csikszentmihalyi (1934-2021). Using Pinckaers' idea of 'fontal knowledge' and Csikszentmihalyi's notion of flow, I interpr

Measurements of the branching fraction ratio B(ϕ→μ+μ−)/B(ϕ→e+e−) with Ds +→π+ϕ and D+→ π+ϕ decays, denoted Rϕπ s and Rϕπ d, are presented. The analysis is performed using a dataset corresponding to an integrated luminosity of 5.4 fb−1 of pp collision data collected with the LHCb experiment. The branching fractions are normalised with respect to the B+ → K+J/ψ(→ e+e−) and B+ → K+J/ψ(→ μ+μ−) decay m

In this text, I develop my earlier argument on the possibility of a non-confessional theological inquiry, and hence an intellectual practice devoted to the classical theological problems that begin with reason rather than faith, at secular universities in Sweden, a country with no state church and many different religions and denominations. I answer the criticism against this tentative proposal by

The four decays, Λb0→ςc(∗)++D(∗)-K-, are observed for the first time using proton-proton collision data collected with the LHCb detector at a center-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 6 fb-1. By considering the Λb0→Λc+D¯0K- decay as reference channel, the following branching fraction ratios are measured to be B(Λb0→ςc++D-K-)B(Λb0→Λc+D¯0K-)=0.282±0.016±0.016±0.00