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In the last decade, breast cancer diagnosis has seen the widespread application of digital breast tomosynthesis (DBT) in screening programs. DBT involves the X-ray tube traversing along an arc trajectory parallel to the patient’s chest wall, acquiring multiple low-dose mammograms from various angles. Reconstruction algorithms process these projection views to generate a stack of slices forming a p
This paper analyses the growth-inequality-poverty nexus in Tanzania. We provide a unique long-term study covering six decades of Tanzanian independence and disentangle the competing narratives concerning growth, inequality, and poverty in the country. We do this by carefully assessing the existing–and at times contradictory–data on growth, inequality, and poverty and by introducing the inequality
Filtering-based probabilistic numerical solvers for ordinary differential equations (ODEs), also known as ODE filters, have been established as efficient methods for quantifying numerical uncertainty in the solution of ODEs. In practical applications, however, the underlying dynamical system often contains uncertain parameters, requiring the propagation of this model uncertainty to the ODE solutio
Background: Mucin degradation is essential for understanding oral microbial adaptation, yet the enzymes involved remain incompletely understood. Herein, we have characterised two mucin-degrading proteases, MdpS and MdpS2, from the oral commensal Streptococcus oralis. Materials and methods: MdpS2 was characterised using physicochemical assays and substrate profiling and was compared to MdpS. Furthe
We study the Coulomb chain where particles are restricted to one dimension and experience three-dimensional Coulomb interactions with their nearest and next-to-nearest neighbours. The distances between consecutive particles are treated as random variables. It is shown that the correlation between clusters of consecutive variables decay exponentially with the number of variables separating them. Th
Nanoplastics are emerging environmental contaminants that increasingly threaten soil ecosystems, yet their effects on microbial behavior remain poorly understood. This is mainly due to the lack of experimental tools capable of directly observing microbial dynamics in situ under realistic soil-like conditions. Here, we present a proof-of-concept system that enables real-time, high-throughput monito
The keystone species concept holds that certain members of an ecological community, despite their low abundance, exert disproportionately large effects on species diversity and composition. In microbial ecology, experimental validation of this concept has been limited because targeted removal of individual species remains technically challenging. Here, we developed a procedure to test the keystone
This exposition takes as its departure the systemic inertia identified within Western Higher Music Education (HME), where education is driven by skill acquisition in a master–pupil format. Such approaches may hinder the growth of adaptable and reflective musicians. We propose an alternative: student-centred learning inspired by artistic research methods. To explicate this, we draw on findings thro
Background: Rehabilitation after Knee Replacement (KR) surgery often entails an extensive rehabilitation in primary care but evidence-based high-quality guidelines are lacking. There is also a knowledge gap regarding current rehabilitation modalities applied in primary care in Sweden. This study aimed to (I) describe rehabilitation in primary care after KR and (II) explore phys-iotherapists’ perce
The European Resuscitation Council (ERC) and the European Society of Intensive Care Medicine (ESICM) have collaborated to produce these post-resuscitation care guidelines for adults, which are based on the International Consensus on Cardiopulmonary Resuscitation Science with Treatment Recommendations (CoSTR) pubished by the International Liaison Committee on Resuscitation (ILCOR). The topics cover
Objective: To identify predictors of GCA in patients with PMR. Methods: Patients with PMR were identified among participants in two population-based health surveys. Those with a registered diagnosis indicating PMR in national and regional registers (the latter including primary care) were included. Medical records from hospitals and primary care were systematically reviewed. PMR diagnoses were ver
This paper shows a FeFET-based analog multi-level unit cell for computing-in-memory applications for Deep Neural Networks (DNN). The FeFET-based unit cell performs input-weight multiplication with a Back-End-Of-Line (BEOL) ferro-electric HZO FeFET device on top of standard 180 nm CMOS circuits. The unit cell works with a feedback mechanism which combines an in-house FeFET device to store weights a
Climate denial and refusal remain central to the ontologies of far-right political projects in many of the countries most responsible for rising temperatures. This article demonstrates how misogyny facilitates the proliferation of obstructionist rhetoric. Specifically, the People’s Party of Canada’s (PPC) climate discourse is analyzed through a feminist lens anchored in Gramscian theorisations of
Creating thermally stable collagen mimetic peptides (CMPs) is a persistent challenge. Nature leverages covalent crosslinkings to stabilize collagen's signature triple helical tertiary structure and higher-order assemblies. Herein, crosslinkings between levodopa (Dopa) and lysine can covalently stabilize the triple helix in CMPs is demonstrated. Since alkaline conditions catalyze the oxidation of t
Gels formed from milk by renneting or acidification under quiescent conditions may subsequently show syneresis, that is, expel liquid (whey) because the gel (curd) contracts. Under quiescent conditions, a rennet-induced milk gel may lose two-thirds of its volume, and up to 90%, or even more, if external pressure is applied. Often, syneresis is undesired, for example, during storage of products lik
Integrated Continuous Biomanufacturing reduces manufacturing costs while maintaining product quality. A key contributor to high biopharmaceutical costs, specifically monoclonal antibodies (mAbs), is chromatography. Protein A ligands are usually preferred but still expensive in the manufacturing context, and batch chromatography under-utilizes the columns' capacity, compromising productivity to mai
The study provides preliminary results from a case comparison of road safety management in three African countries (Tanzania, Ghana, Zambia) with three EU countries, all with a great track record of excellence in traffic safety and practicing Safe Systems principles (Norway and Netherlands & Sweden), based on document analysis and qualitative interviews. Norway, Sweden, and The Netherlands are
