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INTRODUCTION: Immune cells in the tumour microenvironment are associated with prognosis and response to therapy. We aimed to comprehensively characterise the spatial immune phenotypes in the mutational and clinicopathological background of non-small cell lung cancer (NSCLC).METHODS: We established a multiplexed fluorescence imaging pipeline to spatially quantify 13 immune cell subsets in 359 NSCLC
Arbetet med stöd till forskningsdatahantering har utvecklats snabbt de senaste tio åren och kunskap har samlats både i publikationer och universitetsinterna rapporter. Forskarna efterfrågar infrastruktur, stöd och en universitetspolicy att luta sig emot. En analys av aggregerade behov och befintligt stöd visar att universitetet bör utveckla en samlad infrastruktur för forskningsdatalagring med möj
Stille slag (Quiet Beats) is an interdisciplinary performance based on a newly composed choir piece by Louise Alenius with text and dramaturgy by Tanja Diers, directed by Tue Biering in a visual concept by Ida Grarup. On stage are seven classical singers and five former inmates. The former inmates are moving in repetitive patterns in a cell like environment surrounded and ghosted by the singers wh
A theatre performance with and about 4 war veterans with PTSD. In an autobiographical tur de force they take us back to their life changing moments and try to recreate the lives they had before they got crashed by war. Produced by Fix&Foxy together with Betty Nansen Teatret.TURNÉFORESTILLING.
In recent years, since the cloud can provide tremendous advantages regarding storage and computing resources, the industry has been motivated to move industrial control systems to the cloud. However, the cloud also introduces significant security challenges since moving control systems to the cloud can enable attackers to infiltrate the system and establish an attack that can lead to damages and d
Railways are vulnerable to extreme weather events. Some of these are expected to increase in frequency and severity in a warming world, prompting adaptation efforts. To inform these efforts, we have analysed railway operations data from Sweden in the period 2001-2020 to learn more about the past effects of extreme weather events on train delays. We have used a database containing some 1.6 billion
Rörelsekvalité är en faktor som anses vara viktig att utvärdera hos patienter med främre korsbandsskada. Däremot har det inte varit helt klarlagt hur rörelsekvaliteten ska utvärderas. Denna avhandling utvärderar postural orientering som ett kliniskt mått på rörelsekvalitet
Alteration in postural orientation (i.e., the ability to align body segments in relation to each other) can occur due to pain or injury and is suggested to be a risk factor for traumatic knee injuries and early onset and progression of knee osteoarthritis. However, clinical and biomechanical assessment of postural orientation is time-consuming, thus new and faster methods are needed in order to be
Patients referred to orthopeadic care due to longstanding hip and groin pain often suffers from hip-related pain. Hip-related pain such as femoroacetabular impingement syndrome may lead to early onset of hip osteoarthritis. Previous research has shown that patients with longstanding hip and groin pain have poor patient-reported outcomes compared to healthy controls. Also, decreased hip muscle stre
BACKGROUND: Cryptogenic stroke is a heterogeneous condition, with a wide spectrum of possible underlying causes for which the optimal secondary prevention may differ substantially. Attempting a correct etiological diagnosis to reduce the stroke recurrence should be the fundamental goal of modern stroke management.METHODS: Prospective observational international multicenter study of cryptogenic str
Technologies developed since the late eighteenth century differ from earlier forms of technology by being as dependent on world market prices of labour, land and other biophysical resources as on human inventiveness. Yet, whether their outlook is mainstream or heterodox, modern people tend to view technology simply as ingenuity applied to nature, while oblivious of the extent to which it is contin
The spleen contracts during apnea, releasing stored erythrocytes, thereby increasing systemic hemoglobin concentration (Hb). We compared apnea and rebreathing periods, of equal sub-maximal duration (mean 137 s; SD 30), in eighteen subjects to evaluate whether respiratory arrest or hypoxic and hypercapnic chemoreceptor stimulation is the primary elicitor of splenic contraction and cardiovascular re
