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Cervical Spine Computed Tomography Hounsfield Units Accurately Predict Low Bone Mineral Density of the Femoral Neck

STUDY DESIGN: A retrospective cohort.OBJECTIVE: The objective of this study to determine the correlation between Hounsfield unit (HU) measurements from the C4 vertebral body and dual-energy x-ray absorptiometry (DXA) T-score.SUMMARY OF BACKGROUND DATA: Recent attention has turned to the utilization of HU measurements from computed tomography (CT) as a potential screening method for low bone minera

Altered function of arcuate leptin receptor expressing neuropeptide Y neurons depending on energy balance

OBJECTIVE: One of leptin's main targets in the hypothalamus are neuropeptide Y (NPY) neurons, with selective deletion of leptin receptors (Lepr) specifically in Npy neurons resulting in major alterations of energy partitioning between fat and bone mass. However, the specific action of these Npy+/Lepr+ neurons compared to Npy-negative Lepr (Npy-/Lepr+) neurons in regard to energy homeostasis regula

Central sensitization and severity of gastrointestinal symptoms in irritable bowel syndrome, chronic pain syndromes, and inflammatory bowel disease

BACKGROUND: Central sensitization has been suggested as an explanation of the wide range of gastrointestinal and extraintestinal symptoms commonly seen in irritable bowel syndrome (IBS). In this study, the presence and level of central sensitization, and its association to gastrointestinal (GI) symptoms were explored in IBS in comparison with control groups.METHODS: We investigated patients with I

Directions of Longitudinal Relationships between Housing-related Control Beliefs and Activities of Daily Living among People with Parkinson's disease

INTRODUCTION: The gerontological literature suggests that external housing-related control beliefs (HCB) influence activities of daily living (ADL) among older people, but knowledge is scarce for people with Parkinson's disease (PD). This longitudinal study aimed to explore the directions of the relationship between external HCB and ADL among people with PD.METHODS: Baseline (T1) and 3-year follow

Proximal Femur Hounsfield Units on CT Colonoscopy Correlate With Dual-energy X-ray Absorptiometry

BACKGROUND: Quantifying bone mineral density (BMD) on CT using commercial software demonstrates good-to-excellent correlations with dual-energy x-ray absorptiometry (DEXA) results. However, previous techniques to measure Hounsfield units (HUs) within the proximal femur demonstrate less successful correlation with DEXA results. An effective method of measuring HUs of the proximal femur from CT colo

Sex-specific changes in metabolism during the transition from chow to high-fat diet feeding are abolished in response to dieting in C57BL/6J mice

BACKGROUND/OBJECTIVE: Female mice are often excluded from diet-induced obesity studies as they are more resistant to the obesifying effects of a high-fat diet (HFD). However, the underlying mechanisms behind this sex disparity may actually have important implications for the development and management of obesity in humans. Therefore, we systematically investigated the immediate sex-specific effect

In silico identification of Theileria parva surface proteins

East Coast Fever is a devastating African cattle disease caused by the apicomplexan parasite, Theileria parva. Little is known about the cell surface, and few proteins have been identified. Here, we take an in silico approach to identify novel cell surface proteins, and predict the structure of four key proteins.

The Use of Distal Ulnar Hounsfield Units to Predict Future Fragility Fracture Risk

PURPOSE: Distal ulnar Hounsfield unit (HU) measurements obtained from computed tomography (CT) scans of the wrist can be used to accurately screen for low bone mineral density. It is unknown whether HU measurements can also predict the risk of future fragility fractures. Therefore, the purpose of this study was to determine if the HU values of the distal ulna correlate to fragility fracture risk.M

Circulating monocytes and B-lymphocytes in neovascular age-related macular degeneration

BACKGROUND: Individuals with neovascular age-related macular degeneration (AMD) have altered number and distribution of retinal macrophages and show changes in circulating antibodies. We wanted to investigate the corresponding precursors, with subpopulations. We therefore measured monocyte and B-lymphocyte populations in individuals with neovascular AMD.DESIGN: This was an observational case-contr

Glenoid neck Hounsfield units on computed tomography can accurately identify patients with low bone mineral density

BACKGROUND: Osteoporosis is a costly and morbid disease with the first presentation often with a fragility fracture. The purpose of this study was to assess whether Hounsfield unit (HU) measurements on shoulder computed tomography could identify patients at risk of osteoporosis and aid in its diagnosis.METHODS: We identified patients who had both a computed tomography scan of the glenoid and a dua

Frequency of Bone Health Presentations at National Hand Meetings

PURPOSE: The purpose of this study was to determine the frequency with which osteoporosis topics (screening, medical treatment, and fracture prevention) are presented at national hand surgery meetings. This was compared with the frequency of the same topics presented at the Orthopaedic Trauma Association (OTA) annual meetings.METHODS: The annual meeting programs for the American Society for Surger

Measurement of Distal Ulnar Hounsfield Units Accurately Predicts Bone Mineral Density of the Forearm

BACKGROUND: Hounsfield unit (HU) measurement obtained from computed tomography (CT) scans of the wrist is a potential new screening method for low bone mineral density (BMD). We hypothesized that HU measurements of the ulnar head obtained from CT scans would correlate with BMD assessed with dual x-ray absorptiometry (DXA) scans of the forearm.METHODS: Patients with both upper-extremity CT and DXA

Entry-inhibitory role of catechins against SARS-CoV-2 and its UK variant

BACKGROUND: The global pandemic caused by a RNA virus capable of infecting humans and animals, has resulted in millions of deaths worldwide. Severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) infects the lungs, and the gastrointestinal tract to some extent. Rapid structural mutations have increased the virulence and infectivity of the virus drastically. One such mutated strain known as

Cardiac arrhythmias associated with spinal cord injury

CONTEXT/OBJECTIVES: To review the current literature to reveal the incidence of cardiac arrhythmias and its relation to spinal cord injury (SCI).DATA SOURCE: MEDLINE database, 304 hits, and 32 articles were found to be relevant. The relevant articles all met the inclusion criteria: (1) contained original data (2) on cardiac arrhythmias (3) in humans with (4) traumatic SCI.RESULTS: In the acute pha

EXPLORING THE HYDROMECHANICS OF A HETEROGENEOUS POROUS SANDSTONE: COUPLED IN SITU EXPERIMENTS WITH X-RAY AND NEUTRON IMAGING

In geoengineering, such as oil and gas production, geological CO2 storage, geothermal projects, and environmental remediation, a detailed understanding of the hydraulic and mechanical properties of sandstone properties is crucial. Traditional theories on the hydraulic and mechanical behavior of rocks rely on bulk measurements from boundary sensors, which fail to capture complex heterogeneity in st

Posttraumatiskt stressyndrom (PTSD) och komplex PTSD (CPTSD) : En klinisk kunskapsuppdatering

Post-traumatic stress disorder, PTSD, is a psychiatric diagnosis that describes a condition where one or more very traumatic events, that include life-threatening or extreme psychological stress, have left permanent traces of distress that induce sustained suffering. In this clinical overview, we present current updates in diagnostic criteria and a new diagnosis of complex PTSD, and discuss the pr

Experimental investigation of the response of an a-Si EPID to an unflattened photon beam from an Elekta Precise linear accelerator

The characteristics of an Elekta amorphous silicon (a-Si) electronic portal imaging device (EPID) in response to a 6 MV photon beam generated without a flattening filter, an unflattened beam, have been determined. The characteristics were then compared to those for a conventional photon beam generated with a flattening filter in the beam, a flattened beam, in order to determine the suitability of

Many Maids Make Much Noise

The documented artistic research project (doctoral thesis), Many Maids Make Much Noise, comprises a series of artistic projects focused on the social history of the early twentieth-century British militant campaign for votes for women (known as the suffragette movement). The aim is to try out artistic and educational strategies used within that movement, as a means of ‘reading’ these practices and

Utredning, handläggning och behandling av PTSD och CPTSD

Post-traumatic stress disorder (PTSD) is a disruptive condition associated with great suffering. Fortunately, effective treatments are available. Assessment of children and adolescents with symptoms of PTSD is done within the child and adolescent mental health services. Adults are assessed in primary healthcare settings. In complex conditions with psychiatric comorbidity, assessment is conducted i

The safety of cell saver washing all shed mediastinal blood before re-transfusing it to the patient

Introduction: Cardiotomy suction blood is used in cardiopulmonary bypass (CPB) surgery to maintain blood volume in the CPB system, although it is known to contain micro emboli, cytokines and free plasma hemoglobin. Our aim was to investigate whether cell saver washing the cardiotomy suction blood before re-transfusing it is safe. Methods: This is a retrospective study of 1671 elective coronary art