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Clinicopathologic and molecular study of superficial CD34-positive fibroblastic tumours mimicking atypical fibrous histiocytoma (dermatofibroma)
Aims: Superficial CD34-positive fibroblastic tumour (SCD34FT) is an uncommon but distinctive low-grade neoplasm of the skin and subcutis that shows frequent CADM3 expression by immunohistochemistry (IHC). In this study, prompted by an index case resembling ‘atypical fibrous histiocytoma (FH)’ that was positive for CADM3 IHC, we systematically examined a cohort of tumours previously diagnosed as ‘a
Alzheimer's disease genetic pathways impact cerebrospinal fluid biomarkers and imaging endophenotypes in non-demented individuals
INTRODUCTION: Unraveling how Alzheimer's disease (AD) genetic risk is related to neuropathological heterogeneity, and whether this occurs through specific biological pathways, is a key step toward precision medicine. METHODS: We computed pathway-specific genetic risk scores (GRSs) in non-demented individuals and investigated how AD risk variants predict cerebrospinal fluid (CSF) and imaging biomar
FGM modeling of ammonia/n-heptane combustion under RCCI engine conditions
A novel flamelet-generated manifold (FGM) model is introduced, encompassing ignition and flame propagation in ammonia/n-heptane dual-fuel combustion under reactivity-controlled compression ignition (RCCI) engine conditions. To generate the FGM mapping function (FGM tabulation) accounting for multiple combustion modes in RCCI combustion, a novel one-dimensional RCCI configuration (1D-RC) is propose
“A feeling of being part of the future” : a qualitative study on physical therapists’ experiences of delivering digital first-line treatment for hip and knee osteoarthritis
Introduction: Digital options for osteoarthritis (OA) treatment are increasingly available with high patient satisfaction and acceptability. Little is, however, known about physical therapists’ (PT) perception of this treatment modality. Objective: To investigate PT’s experience of delivering digital treatment for hip and knee OA using a smart-phone application. Method: Nine PTs (mean age 36 years
A SIRT7-dependent acetylation switch regulates early B cell differentiation and lineage commitment through Pax5
B lymphopoiesis is orchestrated by lineage-specific transcription factors. In B cell progenitors, lineage commitment is mediated by Pax5, which is commonly mutated in B cell acute lymphoblastic leukemia. Despite its essential role in immunity, the mechanisms regulating Pax5 function remain largely unknown. Here, we found that the NAD+-dependent enzyme SIRT7 coordinates B cell development through d
How Does Legal Culture Matter for Climate Mobilities? A Case Study in an Unplanned Coastal Settlement in Urban Mozambique
This article responds to the general neglect of legal culture in the study of climate mobilities. It presents a case study of climate mobilities in an unplanned settlement in Maputo, Mozambique, exploring how legal culture influenced residents’ decision-making processes as they navigated climate-related risks in their daily lives. We demonstrate that legal culture can facilitate climate mobilities
The Swedish Campaign for Nuclear Disarmament, 1961–1967 : Political Time Orientation and Worldview
The Swedish Campaign for Nuclear Disarmament (SCND) fought the military’s plans to acquire Swedish nuclear weapons and protested the nuclear arms race, 1961–1967. This article presents SCND’s ideological orientation by focusing on temporalities. SCND saw the Second World War as a decisive event and tried to avert a crisis and a dystopia by manifesting remembrance of past nuclear detonations, and b
Larval growth rate is not a major determinant of adult wing shape and eyespot size in the seasonally polyphenic butterfly Melanitis leda
Background: Insects often show adaptive phenotypic plasticity where environmental cues during early stages are used to produce a phenotype that matches the environment experienced by adults. Many tropical satyrine butterflies (Nymphalidae: Satyrinae) are seasonally polyphenic and produce distinct wet- and dry-season form adults, providing tight environment-phenotype matching in seasonal environmen
Klimat, luftföroreningar och hälsa
Prepared for the future? Social work students, ontological insecurity and the turning point in Swedish refugee policies
The year 2015 marked a rupture in the post-war development of refugee reception and integration policies in Sweden. This rupture involved both a radical change in refugee policy and practice, and a rupture in the long-held collective self-image of Sweden as a country with generous reception and integration policies (Scarpa & Schierup 2018). This article responds to the question of how social wThe year 2015 marked a rupture in the post-war development of refugee reception and integration policies in Sweden. This rupture involved both a radical change in refugee policy and practice, and a rupture in the long-held collective self-image of Sweden as a country with generous reception and integration policies (Scarpa & Schierup 2018). This article responds to the question of how social w
Heraldik och valspråk på latin
Living and Non-living Voices and Bodies : Public Secret in the Light of Living Voices
"One solution is: Don't breathe" : Cyborg aesthetics in the music of Lars-Gunnar Bodin
Article in the booklet for the 7 CD box set:Lars-Gunnar Bodin: Retrospective Episodes 1960-1987Introduction to the electroacoustic pieces CYBO I and CYBO II.
Diverse understandings and values of nature at the peace–environment nexus: a critical analysis and policy implications towards decolonial peace
Scholarship in peace and conflict studies is paying increasing attention to the role of the environment for conflict transformation and peacebuilding. However, a closer analysis on how different understandings of “nature” implicate policy proposals and approaches to peacebuilding is lacking. In this study, we provide a critical reflection on the diverse understandings and valuations of nature at t
Insights into the K–Pg extinction aftermath: The Danish Cerithium Limestone Member
The Cretaceous–Palaeogene (K–Pg) mass extinction about 66 Ma ago was one of Earth’s largest mass extinction events. The demise of calcifiers, among others, influenced biogeochemical cycles and changed the conditions for carbonate depo sition in the global ocean. This study addresses the sedimentology and carbonate microfacies of the Cerithium Limestone Member of the Rødvig Formation within the ren
Kinins in bacterial infections
"Idealfigur till påseende" : Inblickar i tillverkning och försäljning av korsettartiklar, 1910-1960
Drivers avoid attentional elaboration under safety-critical situations and complex environments : 17th European Workshop on Imagery and Cognition, Anglia Ruskin University, Cambridge, UK, June 20-22, 2023
In everyday activities where continuous visual awareness is critical such as driving, several cognitive processes pertaining to visual attention are of the essence, for instance, change detection, anticipation, monitoring, etc. Research suggests that environmental load and task difficulty contribute to failures in visual perception that can be essential for detecting and reacting to safety-critica
Cognitive Modelling of Visuospatial Complexity in the Streetscape : 8th International Conference on Spatial Cognition: Cognition and Action in a Plurality of Spaces (ICSC 2021), (Virtual Conference), September 13-17, 2021
Background: Incorporating knowledge about human behaviour and the effect of the environment is a major goal for the design and engineering of human-centred autonomous vehicles. Systems that aim to establish a common interaction ground with humans require systematic modelling of empirically established behavioural norms customised to specific contexts. Aims: Focusing on aspects pertaining to visual
