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Colorectal cancer (CRC) is one of the most common forms of cancer worldwide, with an annual incidence of more than 1 million cases. Despite advancements in the management of CRC, mortality remains high. Accumulating evidence indicates that CRC is a heterogeneous disease, which affects outcome beyond what can be predicted by disease stage and other conventional prognostic factors. Thus, there is a
We have carried out a combined X-ray photoelectron spectroscopy (XPS), ultraviolet photoelectron spectroscopy(UPS), and scanning tunnelling microscopy (STM) study of the C-60-Si(1 1 1) interaction where the XPS/UPS spectrometer and STM are integrated on a single UHV system. This enables a direct comparison of the XPS/UPS spectra with the STM data and eliminates any uncertainty in C-60 coverage mea
Background: The evidence about nitrosamines and heme iron intake and cancer risk is limited, despite the biologic plausibility of the hypothesis that these factors might increase cancer risk. We investigated the association between dietary nitrosamines and heme iron and the risk of prostate cancer among participants of European Prospective Investigation into Cancer and Nutrition (EPIC). Methods: D
Nuclear Quadrupole Resonance (NQR) is a method of de- tection and unique characterization of compounds containing quadrupolar nuclei, commonly found in many forms of ex- plosives, narcotics, and medicines. Typically, multi-pulse sequences are used to acquire the NQR signal, allowing the resulting signal to be well modeled as a sum of exponentially damped sinusoidal echoes. In this paper, we improv
We have observed beta(+)-delayed alpha and p alpha emission from the proton-rich nucleus Mg-21 produced at the ISOLDE facility at CERN. The assignments were cross-checked with a time distribution analysis. This is the third identified case of beta p alpha emission. We discuss the systematic of beta-delayed particle emission decays, show that our observed decays fit naturally into the existing patt
Hypertensive disorders of pregnancy, including preeclampsia, are major contributors to maternal morbidity. The goal of this study was to evaluate the potential of metabolomics to predict preeclampsia and gestational hypertension from urine and serum samples in early pregnancy, and elucidate the metabolic changes related to the diseases. Metabolic profiles were obtained by nuclear magnetic resonanc
Self-organized (Ga,Mn)As nanoclusters, embedded in GaAs and formed during thermal annealing of Ga1-xMnxAs layer at 500 degrees C or 600 degrees C, were studied using Transmission Electron Microscopy (TEM) and Magnetic Force Microscopy (MFM). We found that 10-20 nm large NiAs-type hexagonal MnAs nanocrystals gave magnetic contrast in MFM images, whereas smaller zinc-blende nanoinclusions were not v
We review the recent progress in dynamical and statistical downscaling approaches for west African precipitation and perform a regional climate model (RCM) intercomparison using the novel multi-model RCM data set from the Ensembles-based Predictions of Climate Changes and Their Impacts (ENSEMBLES) and African Monsoon Multidisciplinary Analyses (AMMA) projects. Present RCMs have distinct systematic
Background: The concerted effects of changes in gene expression due to changes in the environment are ultimately reflected in the metabolome. Dynamics of metabolite concentrations under a certain condition can therefore give a description of the cellular state with a high degree of functional information. We used this potential to evaluate the metabolic status of two recombinant strains of Sacchar
ASHEIM B. T., LAWTON SMITH H. and OUGHTON C. Regional innovation systems: theory, empirics and policy, Regional Studies. Interest in regional innovation systems has grown significantly over the past three decades driven partly by advances in theoretical analysis, partly by the growing interest in innovation as a source of competitive advantage, and partly by the need for new policies to address re
Esters of phosphoric acid constitute a sizable fraction of the total phosphorus supply in the environment and thus play an important role in the global phosphorus cycle. Enzymatic hydrolysis of these esters to produce orthophosphate is often a required reaction preceding phosphorus uptake by plants and microorganisms. Generally, adsorption to environmental particles is assumed to limit this proces
Produktion av biogas från gödsel har i flera studier visat sig leda till stora positiva miljöeffekter, i synnerhet vad gäller emissioner av växthusgaser, jämfört med andra förnybara energibärare. Skälet är att produktionen av biogas, utöver att ersätta fossila bränslen, också ger en minskad miljöpåverkan från konventionell hantering av stallgödsel. Trots dessa positiva miljöeffekter utnyttjas dock
Background: The influence of variants at the 9p21 locus on melanoma risk has been reported through investigation of CDKN2A variants through candidate gene approach as well as by genome wide association studies (GWAS). Methods: In the present study we genotyped, 25 SNPs that tag 273 variants on chromosome 9p21 in 837 melanoma cases and 1154 controls from Spain. Ten SNPs were selected based on previ
Syftet med denna studie är att utifrån mitt empiriska material kartlägga och beskriva hur föräldrar till barn intagna på särskilda ungdomshemmen tolkar, definierar och upplever ett behandlingsprojekt, som involverade olika myndigheter, benämnt Motverka Våld och Gäng. Dessutom uppmärksammas hur de anställda samordnarna uppfattades och kategoriserades av föräldrarna. ”Föräldrar” blir i undersökninThe aim of this study is to analyze how mothers with children placed in Swedish juvenile homes interpret, define and perceive, on the one hand, the project “Motverka Våld och Gäng” meaning “Counteract Violence and Gangs”, and on the other hand the role of the Coordinators employed in this project. The mothers who were interviewed spoke about some Coordinators that they appreciated. They then pain
Bet-hedging theory addresses how individuals should optimize fitness in varying and unpredictable environments by sacrificing mean fitness to decrease variation in fitness. So far, three main bet-hedging strategies have been described: conservative bet-hedging (play it safe), diversified bet-hedging (don't put all eggs in one basket) and adaptive coin flipping (choose a strategy at random from a f
Predator-prey interaction strengths in variable environments constitute a fundamental link to the understanding of aquatic ecosystem responses to environmental change. The present study investigates the effects of visibility conditions and prey fish density on predation rates of visually oriented piscivorous Eurasian perch Perca fluviatilis L. This was done in outdoor mesocosm (16 m(2)) experiment
The two-body photodisintegration of He-3 has been investigated using tagged photons with energies from 14-31 MeV at MAX-lab in Lund, Sweden. The two-body breakup channel was unambiguously identified by the (nonsimultaneous) detection of both protons and deuterons. This approach was made feasible by the overdetermined kinematic situation afforded by the tagged-photon technique. Proton-and deuteron-
We present results of a resonant photoemission study of (Zn,Co)O films with Co content between 2% and 7%. The films were grown by Atomic Layer Deposition (ALD) at low temperature of 160 degrees C and show fully paramagnetic behavior. The Co ions are uniformly distributed in the ZnO matrix and are free of foreign phases and metal accumulations as indicated by TEM data. The electronic structure of (
