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We present a prospective multicentre cohort of 20 children with acute lymphoblastic leukaemia (ALL) and cerebral sinus venous thrombosis (CSVT). The study covers a period of 5years and comprises 1038 children treated according to the Nordic Society of Paediatric Haematology and Oncology (NOPHO) ALL 2008 protocol. The cumulative incidence of CSVT was 2%. Sixteen of the thromboses were related to as
OBJECTIVES: We assessed pharmacodynamic (PD) response for the reduced prasugrel 5-mg maintenance dose in very elderly (≥75y; VE) patients. BACKGROUND: In TRITON-TIMI 38, prasugrel 10-mg reduced ischemic events versus clopidogrel 75-mg, but increased bleeding in VE patients. METHODS: We examined PD and active-metabolite pharmacokinetics with prasugrel 5-mg and 10-mg and clopidogrel 75-mg in a three
Lower urinary tract symptoms (LUTS) in men with benign prostatic hyperplasia (BPH) are associated with erectile dysfunction. Alpha-1-adrenoceptor antagonists are effective drugs for treating symptomatic BPH. Clinical data show improvements in LUTS by phosphodiesterase 5 inhibitors. This study aimed to evaluate effects of silodosin, a highly selective α1A-adrenoceptor antagonist, alone or in combin
Psychiatric, physical and biological aspects of posttraumatic stress disorder (PTSD) may be associated with dysfunctions in several cellular processes including nitric oxide (NO) production. NO is synthesized from arginine in a reaction carried out by NO synthase (NOS) enzymes. The recently introduced "global arginine bioavailability ratio" (GABR; ratio of arginine to [ornithine+ citrulline]) has
This study aims to evaluate the direct effects of anthropogenic deforestation on simulated climate at two contrasting periods in the Holocene, similar to 6 and similar to 0.2 k BP in Europe. We apply We apply the Rossby Centre regional climate model RCA3, a regional climate model with 50 km spatial resolution, for both time periods, considering three alternative descriptions of the past vegetation
This report explores the properties of fire-retardant treated wood. This report has investigated the permanence for this material as well as seeing if the process of accelerated aging, which are used to determine the life span of the material, can be comparable to natural aging. The methods used for this report have been a literature and interview study in addition to practical experiments. After
Comets have been a source of fascination throughout the history of man. In recent years, advances in technology have opened up for the study of extrasolar objects, among them exocomets. The first exocomets were observed in the β Pictoris system almost 50 years ago and the system has been of interest ever since. Still, it is not clearly known where these bodies originate from and how they end up in
Examensarbetets titel: Winds of Change: Radikala Förändringar Utan Motstånd Seminariedatum: 11/01-2024 Ämne/kurs: FEKH49, Examensarbete kandidatnivå i Organisation, 15 högskolepoäng Författare: Emil Blomborg och Erik Bäärnhielm Handledare: Stefan Sveningsson Fem nyckelord: Förändring, Identitet, Motstånd, Organisationskultur, Förändringstrategi Syfte: Studien syftar till att belysa och utfo
En kvalitativ studie som syftar till att bidra med en ökad nyansering av mellanchefers roll i organisationsförändringar genom att se till hur de själva uppfattar rollen i fråga och vad den innefattar. Studien behandlar således frågeställningen: ”Hur ser varuhuschefer på sin roll i en organisationsförändring?” För att besvara denna frågeställning har en kvalitativ fallstudie gjorts på sju varuhusA qualitative study about store managers’ role in organizational change. This study aims to further nuance the role of middle managers in organizational change by studying how the middle managers themself perceive this role, as well what it implies. To answer this the following research question was formulated: How do store managers perceive their role in organizational change? In order to addre
Sammanfattning Titel: Handelsvolym och Teoretisk prissättning - Handelsvolymens Påverkan på Teoretisk Prissättning av en Option Enligt Black-Scholes modellen Seminariedatum: 2024-01-11 Kurs: FEKH89 Examensarbete i Finansiering på kandidatnivå, 15 Högskolepoäng Författare: Barsne, Herman; Boström, David; Helmersson, Jacob Handledare: Bengtsson, Elias Nyckelord: Optioner, Handelsvolym, Black-
Samhället präglas av en ökande social acceleration där teknologisk utveckling och strävan efter effektivisering, påverkar arbetslivet och skapar nya sätt för individen att uppleva tid. Genom att tillämpa begrepp som social acceleration, resonans och tid undersöker uppsatsen samspelet mellan dessa i förhållande till de senmoderna fenomenen gränslöst arbete och prekarisering. Målet är att bidra med
Examensarbetets titel: Borta bra men hemma bäst? Seminariedatum: 2024-01-10 Kurs: FEKH89, Examensarbete kandidatnivå i finansiering, 15 högskolepoäng Författare: Christian-Fredrik Klingspor, Hanna Kölerud och Marcus Dagsberg Handledare: Maria Gårdängen Nyckelord: Familjeägda företag, Tobin`s Q, ROA, prestation, Sverige Forskningsfråga: Presterar familjeägda företag bättre än icke familje
This study investigates the routinization of Electronic Health Records (EHR) systems in a Chinese hospital setting, focusing on Yangzhou University Hospital. Utilizing Adaptive Structuration Theory (AST), the research explores the complex interplay between technolo-gy, human agency, and organizational structures in the context of EHR implementation. The study reveals challenges in interoperability
This scientific thesis focuses on the characterisation of the 3He-detector system of the BIFROST instrument under construction on the European Spallation Source. To that end, the position-sensitive 3He proportional counters that make up the detector system was subjected to a factory acceptance test performed at Laboratoire Léon Brillouin Saclay, France. The purpose of this is to prove that the ove
Sustainable finance incorporates actions and policies for economic development, social inclusion, and environmental sustainability. The development of the Sustainable Development Goals (SDGs) by the United Nations became a guide for the transformation towards sustainability and social inclusion. This case study examines the motivations of Swedish Banks’ engagement in sustainable development issues
This study aims to research the effect the conflict between Russia and Ukraine have had on third party countries' economic growth. Employing an econometric model with inspiration from previous research and Solow's growth model with augmentation to include human capital. The research spans the period from 1993 to 2022. The third party countries are categorized into four different groups bas
This project aims to research to which extent the 2018 rollback of the Dodd-Frank Act has affected the derivative trading patterns of medium-sized banks in the U.S. and whether any conclusions can be drawn regarding changes in their risk profiles in regards to derivative markets given the hypothesis that institutions subject to regulation change would increase their risk exposure. To this end, tra
The integration of environmental, social, and governance (ESG) considerations in investment decisions is pivotal, driven by global initiatives and a surge in sustainable investment strategies. This study, therefore, examines the relationship between ESG scores and stock returns over the period 2018-2022, focusing on the European financial, healthcare, and industrial sectors to identify potential d
