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Objective: To investigate the risk of procedure-related major amputation attributable to revascularization for intermittent claudication (IC) in a population-based observational cohort study. Methods: All patients who underwent open or endovascular lower limb revascularisation for IC in Sweden between 12 May 2008 and 31 December 2012 were identified from the Swedish National Quality Registry for V
Background: Little is known about the relative impact of the preoperative symptoms rest pain and tissue loss, and of the arterial segment revascularized, on amputation rate and mortality in patients with chronic limb-threatening ischemia (CLTI). We wanted to investigate this topic further. Method: This population-based observational cohort study involved 10 419 patients revascularized for CLTI in
Objective/background: Chronic limb threatening ischaemia (CLTI) has a high risk of amputation and mortality. Increased knowledge on how sex, comorbidities, and medication influence these outcomes after revascularisation may help optimise results and patient selection. Methods: This population based observational cohort study included all individuals revascularised for CLTI in Sweden during a five
Objectives The aims of this population based study were to describe mid- to long-term amputation risk, cumulative incidence of death or amputation, and differences in pre-operative comorbidities in patients revascularised for lower limb peripheral artery disease (PAD). Methods This was an observational cohort study. Data from the Swedish National Quality Registry for Vascular Surgery (Swedvasc) we
The TIARA (Test Infrastructure and Accelerator Research Area) project funded by the European Union 7th framework programme made a survey of provision of education and training in accelerator science in Europe. This survey highlighted the need for more training opportunities targeting undergraduate-level students. This need is now being addressed by the European Union H2020 project ARIES (Accelerat
The first ESS prototype cryomodule with medium beta cavities named M-ECCTD is being assembled at CEA Saclay. The Q curves of the 4 cavities mounted inside the cryomodule are presented, and the four power couplers have been conditioned at high power before their assembly onto the cavity string. Completion of the M-ECCTD assembly outside clean room is in progress as well as the finalization of the R
Because global sea level during the last interglacial (LIG; 130–115 ka) was higher than today, the LIG is a useful approximate analogue for improving predictions of future sea-level rise. Here, we synthesize sea-level proxies for the LIG in the glaciated Northern Hemisphere for inclusion in the World Atlas of Last Interglacial Shorelines (WALIS) database.We describe 82 sites from Russia, northern Because global sea level during the last interglacial (LIG; 130–115 ka) was higher than today, the LIG is a useful approximate analogue for improving predictions of future sea-level rise. Here, we synthesize sea-level proxies for the LIG in the glaciated Northern Hemisphere for inclusion in the World Atlas of Last Interglacial Shorelines (WALIS) database. We describe 82 sites from Russia, northern
The chemical abundances for five metal-poor stars in and towards the Galactic bulge have been determined from the H-band infrared spectroscopy taken with the RAVEN multi-object adaptive optics science demonstrator and the Infrared Camera and Spectrograph at the Subaru 8.2-m telescope. Three of these stars are in the Galactic bulge and have metallicities between -2.1<[Fe/H] < -1.5, and high [α/Fe]~
Nature-based solutions are actions that use ecological processes to address societal challenges. In riverscapes, for example, revitalising floodplains helps to reduce the risks of peak floods in the lower reaches. At the same time, nature-based solutions often provide multiple co-benefits for people and nature, such as promoting the provision of important ecosystem services and contributing to bio
We measure the surface of CH3NH3PbI3 single crystals by making use of two-photon photoemission spectroscopy. Our method monitors the electronic distribution of photoexcited electrons, explicitly discriminating the initial thermalization from slower dynamical processes. The reported results disclose the fast-dissipation channels of hot carriers (0.25 ps), set an upper bound to the surface-induced r
Dwarf spheroidal galaxies are among the most promising targets for indirect dark matter (DM) searches in γ rays. The γ-ray flux from DM annihilation in a dwarf spheroidal galaxy is proportional to the J-factor of the source. The J-factor of a dwarf spheroidal galaxy is the line-of-sight integral of the DM mass density squared times σannvrel (σannvrel)0, where σannvrel is the DM annihilation cross-
In this paper, characteristic mode analysis is used to gain insight into the operation of millimeter-wave series patch array. It is shown that the series patch array (broadside) mode has lower modal bandwidth and higher resonant frequency than the corresponding mode of a constituting patch element, whereas the other dominant orthogonal (broadside) mode is identical between the array and the single
We present and compare the existing methods of heteroepitaxy of III-Vs on silicon and their trends. We focus on the epitaxial lateral overgrowth (ELOG) method as a means of achieving good quality III-Vs on silicon. Initially conducted primarily by near-equilibrium epitaxial methods such as liquid phase epitaxy and hydride vapour phase epitaxy, nowadays ELOG is being carried out even by non-equilib
OBJECTIVES: The objectives of this exploratory study were to investigate the feasibility of multidimensional diffusion magnetic resonance imaging (MddMRI) in assessing diffusion heterogeneity at both a macroscopic and microscopic level in prostate cancer (PCa).MATERIALS AND METHODS: Informed consent was obtained from 46 subjects who underwent 3.0-T prostate multiparametric MRI, complemented with a
Matrix metalloproteinases 9 (MMP9) are enzymes involved in regulating neuroplasticity in the hippocampus. This, combined with evidence for disrupted hippocampal structure and function in schizophrenia, has prompted our current investigation into the relationship between MMP9 and hippocampal volumes in schizophrenia. 34 healthy individuals (mean age = 32.50, male = 21, female = 13) and 30 subjects
PURPOSE: Diffusion-weighted MRI is sensitive to incoherent tissue motion, which may confound the measured signal and subsequent analysis. We propose a "motion-compensated" gradient waveform design for tensor-valued diffusion encoding that negates the effects bulk motion and incoherent motion in the ballistic regime.METHODS: Motion compensation was achieved by constraining the magnitude of gradient
Multiple sclerosis leads to diffuse damage of the central nervous system, affecting also the normal-appearing white matter. Demyelination and axonal degeneration reduce regional fractional anisotropy in normal-appearing white matter, which can be routinely mapped with diffusion tensor imaging. However, the standard fractional anisotropy metric is also sensitive to physiological variations in orien
Joint relaxation-diffusion measurements can provide new insight about the tissue microstructural properties. Most recent methods have focused on inverting the Laplace transform to recover the joint distribution of relaxation-diffusion. However, as is well-known, this problem is notoriously ill-posed and numerically unstable. In this work, we address this issue by directly computing the joint momen
