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Advanced Monitoring of H2S Injection through the Coupling of Reactive Transport Models and Geophysical Responses

Hydrogen sulfide (H2S), an environmentally harmful pollutant, is a byproduct of geothermal energy production. To reduce the H2S emissions, H2S-charged water is injected into the basaltic subsurface, where it mineralizes to iron sulfides. Here, we couple geophysical induced polarization (IP) measurements in H2S injection wells and geochemical reactive transport models (RTM) to monitor the H2S stora

Sleeping habits and aortic stiffness in middle-aged men and women from the general population: insights from the SCAPIS study

BackgroundThe relationship between sleeping habits and aortic stiffness remains inconclusive and is not fully explored in the European general population.MethodsWe examined cross-sectionally 8659 participants from the Swedish population-based cohort Swedish CArdioPulmonary bioImage Study (SCAPIS), mean age 57.5 years, 52.1% women. A self-administered questionnaire on sleeping habits (duration, qua

Warming-induced contrasts in snow depth drive the future trajectory of soil carbon loss across the Arctic-Boreal region

The Arctic-Boreal region is projected to experience spatially divergent trends in snow depth following climate change. However, the impact of these spatial trends has remained largely unexplored, despite potentially large consequences for the carbon cycle. To address this knowledge gap, we forced a customised arctic version of the dynamic vegetation model LPJ-GUESS with daily CMIP6 outputs from a The Arctic-Boreal region is projected to experience spatially divergent trends in snow depth following climate change. However, the impact of these spatial trends has remained largely unexplored, despite potentially large consequences for the carbon cycle. To address this knowledge gap, we forced a customised arctic version of the dynamic vegetation model LPJ-GUESS with daily CMIP6 outputs from a

High prevalence of FAP+ cancer-associated fibroblasts predicts poor outcome in patients with high-grade serous ovarian cancer with high CD8 T-cell density

Objective: Studies have implied that fibroblasts may act as regulators of immune cells in the tumor microenvironment (TME). We investigated the clinical relevance of fibroblast activation protein (FAP) positive stroma in high-grade serous ovarian cancer (HGSC) in relation to CD8+ lymphocyte's infiltration. Methods: In a discovery cohort (N = 113) of HGSC, expression of FAP and CD8 in the TME was a

Improved DET communication between cellobiose dehydrogenase and a gold electrode modified with a rigid self-assembled monolayer and green metal nanoparticles : The role of an ordered nanostructuration

Efficient direct electron transfer (DET) between cellobiose dehydrogenase from Corynascus thermophilus (CtCDH) and a novel gold electrode platform, obtained by covalent linking of green AuNPs and AgNPs modified with a dithiol self-assembled monolayer, consisting of biphenyl-4,4′-dithiol (BPDT), was presented. The green AuNPs and AgNPs were synthesized using quercetin as reducing agent at room temp

What drives current population trends in forest birds – forest quantity, quality or climate? A large-scale analysis from northern Europe

Changes in forestry practices and on-going climate change may both have large impacts on forest bird populations. However, large-scale analyses of the effects of temporal changes in forest structure on forest bird numbers are largely lacking. We compared temporal trends from two Swedish nationwide long-term monitoring schemes, the Swedish Bird Survey (1998–2015) and the Swedish National Forestry I

Strategies for Empowering activities in Everyday life (SEE 1.0) : study protocol for a feasibility study of an Internet-based occupational therapy intervention for people with stroke

Background: Rehabilitation after stroke seldom focuses on needs related to an active everyday life and the process of change that people must undergo to adapt to an altered capacity and life situation. In particular, occupational therapy in the late phase needs to support clients in adopting sustainable self-initiated management strategies to regain daily activities and an active everyday life. To

Eight Misconceptions about Prostate-Specific Antigen

Prostate-specific antigen (PSA) was discovered in the 1970s, with assays to detect PSA in blood approved by the US Food and Drug Administration in 1986. Almost from the very beginning, its role as a prostate cancer marker has been severely misunderstood. One of the most well-known misconceptions is that prostate cancer detectable by elevated PSA in asymptomatic men requires treatment, irrespective

Biogenic silica accumulation and diatom assemblage variations through the Eocene-Oligocene Transition : A Southern Indian Ocean versus South Atlantic perspective

It is widely interpreted that there is a significant link between climate cooling at the Eocene-Oligocene Transition(EOT; ~34 Ma) and subsequent diatom proliferation in the world’s oceans during the mid to late Cenozoic. Yet,our understanding of biogenic silica flux through the EOT interval is based on limited data from a few sites, andthere are many complications in making a meaningful comparison

Mixing energy as an adjustment tool for aerodynamic behaviour of an inhaled product : In-vitro and in-vivo effects

This paper describes the development of a fixed dose dry powder combination of indacaterol maleate (Inda) and glycopyrronium bromide (Glyco) in Easyhaler® inhaler for a comparative pharmacokinetic (PK) study, as well as the outcome of such a study. The development aim was to produce formulations with three different in vitro dispersibility profiles for both Inda and Glyco. This so-called ‘rake’ ap

Distribution of intranasal naloxone to potential opioid overdose bystanders in Sweden : Effects on overdose mortality in a full region-wide study

Objectives Distribution of take-home naloxone is suggested to reduce opioid-related fatalities, but few studies have examined the effects on overdose deaths in the general population of an entire community. This study aimed to assess the effects on overdose deaths of a large-scale take-home naloxone programme starting in June 2018, using an observational design with a historic control period. Desi