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Background: The collection and sharing of genomic and health data underpins global efforts to develop genomic medicine services. 'Your DNA, Your Say' is a cross-sectional survey with the goal of gathering lay public attitudes toward the access and sharing of deoxyribonucleic acid (DNA) information and medical information. It suggests significant international variation in the willingness to share

Introduction: The relationship between urate and biomarkers for Alzheimer's disease (AD) pathophysiology has not been investigated. Methods: We examined whether serum concentration of urate was associated with cerebrospinal fluid biomarkers, amyloid beta (Aβ)42, Aβ40, phosphorylated tau (p-tau), total tau (t-tau), neurofilament light (NfL), and Aβ42/Aβ40 ratio, in cognitively unimpaired 70-year-ol

The oxidation and reduction of an Ir(100) surface using 2.5, 5, and 10 mbar O2partial pressure and a sample temperature of 775 K have been studied by using high-energy surface X-ray diffraction (HESXRD) which allowed to record large volumes of reciprocal space in short time periods. The complex 3D diffraction patterns could be disentangled in a stepwise procedure. For the 2.5 mbar experiment the m

Background: Temporality and the embodiment of time is an important dimension in different recovery models, as well as in drug users’ recovery stories. Aim: The main objective of this article is twofold: first, to perform a critical analysis of prominent recovery models and their multiple temporalities, and second, to explore of how female drug users, enrolled in drug treatment, narrate their recovTemporality and the embodiment of time is an important dimension in different recovery models, as well as in drug users' recovery stories. Aim: The main objective of this article is twofold: fi rst, to perform a critical analysis of prominent recovery models and their multiple temporalities, and second, to explore of how female drug users, enrolled in drug treatment, narrate their recovery process

Feedforward control can be considered as the most well-known control approach to deal with measurable disturbances. It started to be used almost 100 years ago, and since then it is being used in most industrial processes. It is a very simple technique that has been used typically as a complement to PID control, although it can be combined with any feedback controller. The feedforward control desig

I det här kapitlet presenteras ett dialogfilosofiskt perspektiv på lyssnande som utgår från antagandet att samtalets båda parter är lika aktiva och att samtal kännetecknas av både dialog och koordination mellan den som talar och den som lyssnar. Författarens beskrivning av det dialogiska lyssnande bygger på centrala tankegångar i Martin Bubers dialogfilosofi. I kapitlet genomförs även en kritisk g

En journalist gör intervjuer i en rad olika sammanhang. Ibland till en snabb nyhetsartikel som ska ut på sajten direkt, andra gånger till ett reportage som ska publiceras eller sändas längre fram i tiden. Under intervjun är det mycket att hålla reda på och det är lätt att tappa tråden. Journalisten ska leda intervjun, tänka på vinkeln, ställa följdfrågor, anteckna eller spela in, och också möta ol

In this paper, we present a review of how the various aspects of any study using an eye tracker (such as the instrument, methodology, environment, participant, etc.) affect the quality of the recorded eye-tracking data and the obtained eye-movement and gaze measures. We take this review to represent the empirical foundation for reporting guidelines of any study involving an eye tracker. We compare

Sverige är ett mångkulturellt land i vilket ca 20 procent av befolkningen är utrikes födda. Här lever människor som tillhör olika befolkningsgrupper med skiftande kulturella bakgrunder och livsstilar. Det innebär att svensk besöksnäring idag kommunicerar med en mycket diversifierad svensk målgrupp. Kunskapsläget om personer med utländsk bakgrunds turismkonsumtion i Sverige är dock begränsad. Det fSweden is a multicultural country in which about 20 percent of the population has a foreign background. People who belong to different population groups live here and have diverse cultural backgrounds and lifestyles. This means that the Swedish tourism and hospitality industry today communicates with a very diversified Swedish target group.This report, which is the result of a commissioned researc

This thesis consists of four self-contained papers in the economics of education. The first chapter examines the importance of instruction time for student achievement on international assessments. The second chapter identifies the effect of sibling gender on education and how this effect varies according to traditional inheritance customs. The third chapter studies the effect of more informative

Estimating the gaze direction with a digital video-based pupil and corneal reflection (P-CR) eye tracker is challenging partly since a video camera is limited in terms of spatial and temporal resolution, and because the captured eye images contain noise. Through computer simulation, we evaluated the localization accuracy of pupil-, and CR centers in the eye image for small eye rotations (≪ 1 deg).

The role of patient participation in forensic psychiatric care is unclear, but has been emphasised as important in recent research. This study aims to describe patients’ lived experiences of participation in high-security, forensic psychiatric settings. Sixteen patient interviews were performed in this phenomenological study and analysed with a Reflective Lifeworld Research approach (RLR). Results

This paper aims to develop a model for calculating the hydraulic and water quality parameters of wastewater within sewers. Information from the wastewater collection network and the transmission line in Birjand were used to verify the model performance. The parameters used for modelling quality changes include the yield constant for biomass (YH), the maximum specific growth rate (μH), the saturati

The crises that cities face—such as climate change, pandemics, economic downturn, and racism—are tightly interlinked and cannot be addressed in isolation. This paper addresses compound urban crises as a unique type of problem, in which discrete solutions that tackle each crisis independently are insufficient. Few scholarly debates address compound urban crises and there is, to date, a lack of inte

We analyze a frequent but undertheorized form of structural injustice, one that arises due to the difficulty of reaching numerically equitable representation of underrepresented subgroups within a larger group. This form of structural injustice is significant because it could occur even if it were possible to completely eliminate bias and overt discrimination from hiring and recruitment practices.

The selection of basis sets is very important for multiconfigurational wave function calculation, due to a balance between a desired accuracy and computational costs. Recently, the atomic natural orbital-relativistic (ANO-R) basis set was published as a suggested replacement for the ANO-RCC basis set for scalar-relativistic correlated calculations Zobel et al (2021 J. Chem. Theory Comput. 16 278-2

Marine ecosystems are currently facing a variety of anthropogenic perturbations, including climate change. Trophic differences in response to climate change may disrupt ecological interactions and thereby threaten marine ecosystem function. Yet, we still do not have a comprehensive understanding of how different trophic levels respond to climate change stressors in marine ecosystems. By including

This article introduces a special issue on the contribution of social science to addressing transformations to sustainability. Articles underline the importance of embracing theoretically rooted, empirically informed, and collaboratively generated knowledge to address sustainability challenges and transformative change. Emphasis is placed on the role of the social sciences in elaborating on the po

Diabetes is the result of dysregulation of both insulin and glucagon. Still, insulin has attracted much more attention than glucagon. Glucagon is released from alpha cells in the islets of Langerhans in response to low glucose and certain amino acids. Drugs with the primary aim of targeting glucagon signalling are scarce. However, glucagon is often administered to counteract severe hypoglycaemia,