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Cisterna magna cannulation (CMc) is a straightforward procedure that enables direct access to the cerebrospinal fluid (CSF) without operative damage to the skull or the brain parenchyma. In anesthetized rodents, the exposure of the dura mater by blunt dissection of the neck muscles allows the insertion of a cannula into the cisterna magna (CM). The cannula, composed either by a fine beveled needle
We test asteroseismic radii of Kepler main-sequence and subgiant stars by deriving their parallaxes which are compared with those of the first Gaia data release. We compute radii based on the asteroseismic scaling relations as well as by fitting observed oscillation frequencies to stellar models for a subset of the sample, and test the impact of using effective temperatures from either spectroscop
In recent years, there has been significant shift from rigid development (RD) toward agile. However, it has also been spotted that agile methodologies are hardly ever followed in their pure form. Hybrid processes as combinations of RD and agile practices emerge. In addition, agile adoption has been reported to result in both benefits and limitations. This exploratory study (a) identifies developme
Cleaning is an inevitable, and often costly, part of most membrane filtration plants. The economic assessment of cleaning costs is often rather arbitrary when researchers design and estimate costs of a membrane plant in a new application. Severity of fouling, operation conditions, cleaning agents and cleaning frequency all influence the costs for membrane cleaning. In addition to the costs of the
Biorefineries are the backbone of “white biotechnology”, the 3rd wave of biotechnology which aims to replace classic C2/C3 chemistry by biotechnological processes. In analogy to petrorefineries biorefineries aim at the integrated and simultaneous production of bulk products, as e.g. biofuels, or biopolymers, heat and power, using biomass. In order to avoid any competition with food production the
Protein-protein interactions play important roles in regulating human aquaporins (AQP) by gating as well as trafficking. While structural and functional studies have provided detailed knowledge of AQP transport mechanisms, selectivity as well as gating by conformational changes of loops or termini, the mechanism behind how protein-protein interactions control AQP-mediated water transport through c
The production of 1 ton of PVC requires 2.0 - 2.5 m3 of demineralised water. Some of the water is lost in the process, e.g. as vapor during the drying of the PVC or as sealing water, while approx. 80% of the water could potentially be recycled. In today’s installations only about 20 – 25% of the water recovered by the PVC decanter is used for flushing of the facilities, while 75 – 80% is discharge
I höst är det 50 år sedan Skärholmens centrum invigdes, ett av de områden som tydligast kommit att symbolisera det svenska miljonprogrammet. Men rekordårens bostadspolitik styrdes inte av en kallhamrad socialdemokratisk människosyn.
„White biotechnology“- the third and latest wave of biotechnology - is aiming to replace the well-established C2/C3 chemistry based on oil and gas by biological processes. The backbone of biotechnology is the conversion by fermentation which is widely established in the production of antibiotics, enzymes, bioethanol and organic acids. One of the key concepts related to “white biotechnology” are so
Every living organism is made up of cells, the smallest structural and functional unit of life. These organisms can further be classified on the basis of cell number as single-cell or multi-cell organism. Over time these primitive organisms have evolved leading to the formation of more complex machinery in higher organism. While it is tough and tedious to calculate the exact number of cells in theWater is an essential compoment of every living orgamism and forms a major part of the human body. Regulated water transport is crucial for proper cell functioning and body homeostasis. Cell, the smallest structural and functional unit of life, uses specialized water conducting pores made up of proteins to transport water across the plasma membrane by facilitated diffusion.The discovery of one of
1. IntroductionThe third and latest wave of biotechnology is the so called „white biotechnology“ aiming to replace the C2/C3 chemistry based on oil and gas by biological processes. The backbone of biotechnology is the conversion by fermentation which is widely established in the production of antibiotics, enzymes, bioethanol and organic acids. In the past, fermentation processes had to partly comp
Biorefineries are integrated biotech facilities aiming on full utilization of feedstock for the simultaneous production of e.g. food, biofuels and biochemicals. This presentation will provide an overview supported by case and application studies on the integration of membrane processes into biorefineries. Starting with the pre-treatment of the raw material e.g. wood biomass or starch, micro- (MF)
Champs d'étoiles is a musical suite that builds on texts and thoughts on the pilgrimage as a quest for deeper insights into the timeless mystery of being human. The work is also about musical timelessness. I have always been deeply fascinated by the music and instruments from the Renaissance and Baroque eras and this work is about new music for period instruments. The close collaboration with the
Since the first description of microRNAs (miRNAs) in 1993 (1) a large and growing number of studies has explored their roles across a variety of biomedical research disciplines, including lung biology. According to GENCODE (version 27) (2), 1881 of the >7,500 human small non-coding RNAs are miRNAs. These 20–25 nucleotide-long, regulatory RNAs are involved in the translational regulation of gene ex
The aim of the study was to explore trajectories of breathlessness intensity by function and life-limiting illness diagnosis in the last 3 weeks of life in palliative care patients. A prospective, consecutive cohort study obtained point-of-care data of patients of Silver Chain Hospice Care Service (Perth, Australia) over the period 2011–2014 (n=6801; 51494 data-points). Breathlessness intensity (0
Lymph node metastasis is the most important prognostic characteristic of colorectal cancer. Carcinoembryonic antigen messenger RNA was shown to detect tumor cells that have disseminated to lymph nodes of colorectal cancer patients and to be at least as good as the hematoxylin and eosin method to predict survival in colorectal cancer patients. CXCL17 was recently shown to be ectopically expressed i
Data from the SDSS-IV/Apache Point Observatory Galactic Evolution Experiment (APOGEE-2) have been released as part of SDSS Data Releases 13 (DR13) and 14 (DR14). These include high-resolution H-band spectra, radial velocities, and derived stellar parameters and abundances. DR13, released in 2016 August, contained APOGEE data for roughly 150,000 stars, and DR14, released in 2017 August, added about
Species from the genus Phytophthora are well represented among organisms causing serious diseases on trees. Phytophthora plurivora has been implicated in long-term decline of woodland trees across Europe. Here we present a draft genome sequence of P. plurivora, originally isolated from diseased European beech (Fagus sylvatica) in Malmö, Sweden. When compared with other sequenced Phytophthora speci
