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The power exponent α in the temperature dependence of laminar burning velocity [Formula presented]=[Formula presented]α is usually considered an empirical parameter extracted from measurements performed at different temperatures. In this paper an analytical derivation of α is proposed, calculating the power exponent from the overall activation energy as: αTu 0→Tu =[Formula presented]·X+x. This rel

The chemistry of para-xylene oxidation in laminar premixed flames has been analyzed using new experimental data on flame propagation at atmospheric pressure and flame structure of low-pressure stoichiometric flame. Atmospheric pressure laminar burning velocities of para-xylene + air flames were determined using the heat flux method at initial temperatures of 328 and 353 K over the equivalence rati

Local governments’ limited mandate and capacity to adequately deal with increasing climate risk and impacts means that citizen engagement is becoming increasingly important for adapting to hazards such as floods and storms. Stronger collaborative approaches are urgently needed. At the same time, there is little research and hardly any empirical evidence on what inspires adaptation engagement in di

In most industrialized countries, there are substantial gender differences in field of study, resulting in gender segregated labor markets. The present research (N = 457, M age = 14.98) investigated a diverse range of predictors of Swedish adolescents’ choice of preparatory (STEM; humanistic) and terminal (e.g., electrician; health care) programs. The results revealed that social identity related

A significant proportion of the psychotherapy in Sweden is delivered by psychology trainees at special educational clinical departments within the universities. The aim of this study was to investigate the effectiveness of the treatments at three clinics measured by outcomes of psychiatric symptoms and functioning (Clinical Outcomes in Routine Evaluation – Outcome Measures) and interpersonal probl

Due to the overpopulation in the main cities and shortage of water in Egypt, finding new possible reclamation areas becomes an urgent necessity. The area northwest of El Sadat city can be considered one of the most promising new reclamation areas. This study focuses on detecting the groundwater aquifers, delineating the best localities to drill groundwater boreholes, and evaluation of the groundwa

For many years, delivering drug molecules across the blood brain barrier has been a major challenge. The neuropeptide nerve growth factor is involved in the regulation of growth and differentiation of cholinergic neurons and holds great potential in the treatment of stroke. However, as with many other compounds, the biomolecule is not able to enter the central nervous system. In the present study,

In the era of large-scale surveys of stars in the MilkyWay, stellar ages are crucial for studying the evolution of the Galaxy.But determining ages of field stars is notoriously difficult; therefore, we attempt to determine benchmark ages for the extensively studied Gaia benchmark stars which can be used for validation purposes. By searching the literature for age estimates from different methods a

BACKGROUND: Traumatic brain injury (TBI) and spinal cord injury (SCI) are increasingly recognised as global health priorities in view of the preventability of most injuries and the complex and expensive medical care they necessitate. We aimed to measure the incidence, prevalence, and years of life lived with disability (YLDs) for TBI and SCI from all causes of injury in every country, to describe

BACKGROUND: Efforts to establish the 2015 baseline and monitor early implementation of the UN Sustainable Development Goals (SDGs) highlight both great potential for and threats to improving health by 2030. To fully deliver on the SDG aim of "leaving no one behind", it is increasingly important to examine the health-related SDGs beyond national-level estimates. As part of the Global Burden of Dise

In this study, the use of cubosomes for topical delivery of the antimicrobial peptide (AMP) LL-37 was investigated. Topical delivery of AMPs is of great interest for treatment of skin infections caused by bacteria, such as Staphylococcus aureus. AMP containing cubosomes were produced by three different preparation protocols and compared: (i) pre-loading, where LL-37 was incorporated into a liquid

BACKGROUND: The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017 comparative risk assessment (CRA) is a comprehensive approach to risk factor quantification that offers a useful tool for synthesising evidence on risks and risk-outcome associations. With each annual GBD study, we update the GBD CRA to incorporate improved methods, new risks and risk-outcome pairs, and new data

BACKGROUND: The Global Burden of Diseases, Injuries, and Risk Factors Study 2017 (GBD 2017) includes a comprehensive assessment of incidence, prevalence, and years lived with disability (YLDs) for 354 causes in 195 countries and territories from 1990 to 2017. Previous GBD studies have shown how the decline of mortality rates from 1990 to 2016 has led to an increase in life expectancy, an ageing gl

BACKGROUND: Global development goals increasingly rely on country-specific estimates for benchmarking a nation's progress. To meet this need, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 estimated global, regional, national, and, for selected locations, subnational cause-specific mortality beginning in the year 1980. Here we report an update to that study, making use

BACKGROUND: Assessments of age-specific mortality and life expectancy have been done by the UN Population Division, Department of Economics and Social Affairs (UNPOP), the United States Census Bureau, WHO, and as part of previous iterations of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD). Previous iterations of the GBD used population estimates from UNPOP, which were not d

BACKGROUND: Benchmark datasets are essential for both method development and performance assessment. These datasets have numerous requirements, representativeness being one. In the case of variant tolerance/pathogenicity prediction, representativeness means that the dataset covers the space of variations and their effects.RESULTS: We performed the first analysis of the representativeness of variat

This article uses the concept of cultural citizenship to understand engagement in political comedy. The concept stresses popular culture’s value for identity and community construction, as well as the importance of learning about and respecting others. Using empirical work on Swedish young adult political comedy audiences in the form of data from in-depth interviews and focus groups, the article a

The last decade has seen a sharp increase in the number of scientific publications describing physiological and pathological functions of extracellular vesicles (EVs), a collective term covering various subtypes of cell-released, membranous structures, called exosomes, microvesicles, microparticles, ectosomes, oncosomes, apoptotic bodies, and many other names. However, specific issues arise when w

This paper focuses on the use of the Compound Past (CP) found in a set of epistolary letters from the 18th and 19th centuries' Uruguay. It is claimed that the CP already at this time encodes situations that are conceptualized within a temporal frame of indeterminacy. All the cases of CP in 66 letters are analyzed according to its contexts – with or without temporal determinants; in colocational en