Changes in the immune system induced by tyrosine kinase inhibitors (TKI) have been shown to positively correlate with therapy responses in chronic myeloid leukemia (CML). However, only a few longitudinal studies exist and no randomized comparisons between two TKIs have been reported. Therefore, we prospectively analyzed the immune system of newly diagnosed CML patients treated with imatinib (n = 2

Rationale and Objectives: Emphysema is a hallmark of chronic obstructive pulmonary disease. The primary aim of this study was to investigate inter- and intraobserver agreement of visual assessment of mild emphysema in low-dose multidetector computed tomography of subjects in the pilot SCAPIS in order to certify consistent detection of mild emphysema. The secondary aim was to investigate the perfor

Objective: The occurrence of Helicobacter pylori (HP) and clarithromycin resistant HP (crHP) have not been investigated longitudinally in the Swedish childhood population. The aims were to study the prevalence of gastric HP-DNA and crHP strains in a cohort of children living in the southernmost parts of Sweden who were investigated with upper endoscopy between 2005 and 2016. Methods: HP colonisati

Vi vill studera processen bakom högskolans tillkomst och dess konsolidering och utveckling. Hur blir ett universitet till?Malmö högskolas officiella födelsedag var den första juli 1998. De första tankarna på en högskola i Malmö – då tänkt som en filial till Lunds universitet – hade börjat ta form under våren 1994. Bakgrunden till högskolans tillkomst låg också i Malmös ekonomiska kräftgång med en

We propose a new structure for the variational auto-encoders (VAEs) prior, with the weakly informative multivariate Student’s t-distribution. In the proposed model all distribution parameters are trained, thereby allowing for a more robust approximation of the underlying data distribution. We used Fashion-MNIST data in two experiments to compare the proposed VAEs with the standard Gaussian priors.

Neuroprotection has proven clinically unsuccessful in subarachnoid hemorrhage. We believe that this is because the major component in the early damage pathway, the vascular wall, has not been given the necessary focus. U0126 is a potent inhibitor of vascular phenotypical changes, exemplified by functional endothelin B (ETB) receptor upregulation. The current study aimed to determine the optimal do

The global spread of antibiotic resistance among Enterobacteriaceae is largely due to multidrug resistance plasmids that can transfer between different bacterial strains and species. Horizontal gene transfer of resistance plasmids can complicate hospital outbreaks and cause problems in epidemiological tracing, since tracing is usually based on bacterial clonality. We have developed a method, based

Malignancy order is an imperative advance in biomarker distinguishing proof. Creating machine learning techniques that effectively anticipate tumor subtypes can help in distinguishing potential disease biomarkers. In this critique, we have introduced ensemble classification approach and contrasted its execution with other characterization approaches. PDAC microarray-based gene expression given in

Health services will change dramatically as the prevalence of home healthcare increases. Only technologically advanced acute care will be performed in hospitals. This-along with the increased healthcare needs of people with long-term conditions such as stroke and the rising demand for services to be more person-centred-will place pressure on healthcare to consider quality across the continuum of c

The geometric isomers (E,E)-, (E,Z)-, (Z,E)-, and (Z,Z)-8,10-dodecadien-1- yl acetate were identified as sex pheromone components or sex attractants in the tribes Eucosmini and Grapholitini of the tortricid subfamily Olethreutinae. Species belonging to the more ancestral Tortricinae were not attracted. Each one isomer was behaviourally active in males of Cydia and Grapholita (Grapholitini), either

The catches of bark beetles (Coleoptera: Scolytidae) were compared between attractive traps releasing semiochemicals and passive traps (cylindrical sticky screens hung, at 10 heights of 0.7-11.5 m, on poles). A central attractive-trap pole was surrounded by three passive-trap poles spaced 50 or 100 m away at the apices of an equilateral triangle. The catches of Tomicus piniperda and other scolytid

The knowledge about reemergence of parent spruce bark beetles Ips typographus. their dispersal, and production of a second brood is reviewed. A majority of the beetles reemerge after their first brood. The process is mainly determined by temperature but high breeding density decreases the average time spent in the tree. The difference between males and females in reemergence seems to be small. In

The glutamate transporter 1 (GLT1) is upregulated during astrocyte development and maturation in vivo and is vital for astrocyte function. Yet it is expressed at low levels by most cultured astrocytes. We previously showed that maturation of human and mouse stem cell-derived astrocytes - including functional glutamate uptake - could be enhanced by fibroblast growth factor (FGF)1 or FGF2. Here, we

Cerebral palsy (CP) is present in about 200 children per birth-year cohort in Sweden. From 2001 to 2016, the annual number of immigrants to Sweden with CP enrolled at the (re)habilitation services increased from less than ten to 40-90 individuals per year; about 70 % came to Sweden as refugees. At a group level, children with CP born abroad had greater functional impairment than children born in S