The complex pathophysiology underlying biological aging creates challenges for identifying biomarkers associated with frailty. This longitudinal, nontargeted proteomics study aimed to identify proteins associated with frailty, particularly the change from nonfrail to frail. The population-based Osteoporosis Prospective Risk Assessment cohort includes women all of whom are 75 years old at inclusion

The majority of single-family houses in Sweden are affected by deteriorations in building envelopes as well as heating, ventilation and air conditioning systems, since they are about 30 years old. Theses house are therefore in need of extensive renovation, which provides an excellent opportunity to incorporate energy efficiency measures to reduce both the energy consumption and also operational. A

Sweden passed legislation to achieve a target of net zero greenhouse gas emissions by the end of 2045. The Energy Performance of Building Directive further obliged European countries to ensure zero-energy building codes and improve the quality of indoor environments when buildings are renovated, as approximately 40% of total greenhouse gas emissions in Sweden are produced while heating buildings.

This study examines the views of stakeholders involved in house renovations regarding the one-stop-shop business concept innovation, and assesses their level of preparedness to adopt such a concept in order to enter the promising market of detached house renovations. The investigation is based on 25 interviews with construction SMEs owners, real estate agents and loan consultants, and on a concept

Buildings are responsible for 40% of energy consumption and 36% of CO2 emissions in the EU. Sweden andDenmark are cold climatic countries with strong demand for space heating and hot water in the residential sector. Large section of the detached houses in these countries are built more than 30 years ago and need refurbishment. Despite of huge energy saving potentials with deep renovation of these

A novel energy management (EM) approach is introduced, integrating core elements of collective intelligence (CI) and reinforcement learning (RL) and called CIRLEM. It operates by distributing a flexibility signal from the energy supplier to agents within the grid, prompting their responsive actions. The flexibility signal reflects upon the collective behaviour of the agents in the grid and agents

A new concept has been developed for characterizing the real-time evolution of the three-dimensional pore and lamella microstructure of bread during baking using synchrotron X-ray microtomography (SRµCT). A commercial, combined microwave-convective oven was modified and installed at the TOMCAT synchrotron tomography beamline at the Swiss Light Source (SLS), to capture the 3D dough-to-bread structu

This thesis focuses on the removal of organic micropollutants and transformation products using ozone and activated carbon treatment processes. A combination of 14C-labeled and non-radiolabeled organic micropollutants was used to study aspects of micropollutant removal from novel perspectives. 14C-labeled ozone transformation products (OTPs) were generated by ozonation of 14C-labeled micropollutan

The Eastern Orthodox Churches in post-communist Eastern Europe are embroiled in long-running conflicts over ownership of territory, saints, sites, nations, and history. These often violent conflicts reflect political and national rivalries, most explicitly in former Yugoslavia and Ukraine. They are often understood as simplified ethnic-national tensions with religious overtones, but, as this book

Accurate estimate of stem volume is crucial to forest management. In this study, we developed allometric equations of stem volume of Acacia auriculiformis after destructive harvesting of 48 individual trees. We also took digital photographs of each sample tree just before destructive harvesting from the felling operations of Bangladesh Forest Department in short rotation (10-15 years) plantations.

High-grade gastroenteropancreatic (HG-GEP) neuroendocrine neoplasms (NENs) are highly aggressive cancers. The molecular etiology of these tumors remains unclear, and the prevalence of pathogenic germline variants in patients with HG-GEP NENs is unknown. We assessed sequencing data of 360 cancer genes in normal tissue from 240 patients with HG-GEP NENs; 198 patients with neuroendocrine carcinomas (