Characterization of immune niches in non-small cell lung cancer
Lung cancer, particularly non-small cell lung cancer (NSCLC), is a leading cause of cancer-related deaths globally. Immunotherapy using immune checkpoint inhibitors (ICI) is a potent treatment for NSCLC; however, long-term response is limited in the majority of patients and there is a lack of predictive biomarkers. Tertiary lymphoid structures (TLS) may serve as biomarkers for predicting ICI respo