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Multiple Windows for Estimation of Locally Stationary Transients in the Electroencephalogram
In this paper, multiple windows, optimal for locally stationary processes (MW-LSP) are used to estimate the spectrogram of the electroencephalogram (EEG) where we focus on the ability to estimate transient frequency changes. A peak of known frequency was evoked in the EEG spectrum in a predetermined time interval, by using a 9 Hz flickering light. We investigate the multiple windows corresponding
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Stabilization of the state of equilibrium of affine system controlled by saturating control is investigated. Saturating stabilizing control is designed by means of rescaling of control laws after linearization of the system under feedback control. A method for estimation of the stabilized region of state space is provided. As an example, a solution to the task of stabilization of the orientation o
Bose-Einstein correlations in W+W- events at LEP2
Bose-Einstein correlations (BEC) between final state particles in the reaction e(+)e(-) -> W+ W- -> q(1)(q(2)) over barq(3)(q(4)over bar>) over bar) have been studied. Data corresponding to a total integrated luminosity of 550 pb(-1), recorded by the DELPHI detector at centre-of-mass energies ranging from 189 to 209 GeV, were analysed. An indication for inter-W BEC between like-sign particles has
BAY 81-8973 safety and efficacy for prophylaxis and treatment of bleeds in previously treated children with severe haemophilia A: results of the LEOPOLD Kids Trial.
BAY 81-8973, a full-length, unmodified, recombinant factor VIII (FVIII) in development for treatment of haemophilia A, has the same primary amino acid sequence as Bayer's sucrose-formulated recombinant FVIII but is produced with more advanced manufacturing technologies.
Loss of size-selectivity of the glomerular filtration barrier in rats following laparotomy and muscle trauma.
Post-traumatic microalbuminuria may be caused by either charge- or size-selective alterations in the glomerular filtration barrier, or both, and/or to a reduction in proximal tubular protein reabsorption (PTR). This study was performed to elucidate the pathophysiology of the increases in glomerular permeability occurring in rats exposed to laparotomy or to laparotomy and muscle trauma. In anaesthe
Allvar Gullstrand (1862-1930) - the Gentleman with the Lamp.
This is a biography of Allvar Gullstrand (1862-1930) on the occasion of the centennial of his 1911 Nobel Prize in physiology or medicine. We reviewed pertinent literature and we did archival studies at the Uppsala University Library and the Regional State Archives at Lund as well as the Nobel Archives at the Royal Swedish Academy of Sciences in Stockholm. Allvar Gullstrand was a brilliant scientis
Time to start of cardiopulmonary resuscitation and the effect of target temperature management at 33°C and 36°C.
The optimal temperature during targeted temperature management (TTM) for comatose patients resuscitated from out-of-hospital cardiac arrest is unknown. It has been hypothesized that patients with long no-flow times, for example those without bystander CPR would have the most to gain from temperature management at lower temperatures.
Effects of pH management during selective antegrade cerebral perfusion on cerebral microcirculation and metabolism: alpha-stat versus pH-stat
BACKGROUND: Selective cerebral perfusion (SCP) is used for extending the period during which surgical procedures can be safely performed. We sought to determine the direct effects of pH management on cerebral microcirculation and metabolism during SCP. METHODS: An experimental SCP porcine model was created by selectively allowing cold perfusate only into the bicarotid brachiocephalic trunk during
Bureaucracies and Judgmental Autonomy: Film Consultants in a Public Film Institute
Binding of factor VIIa to tissue factor on human fibroblasts leads to activation of phospholipase C and enhanced PDGF-BB-stimulated chemotaxis
Tissue factor (TF) is the cellular receptor for factor FVIIa (FVIIa), and the complex is the principal initiator of blood coagulation. The effects of FVIIa binding to TF on cell migration and signal transduction of human fibroblasts, which express high amounts of TF, were studied. Fibroblasts incubated with FVIIa migrated toward a concentration gradient of PDGF-BB at approximately 100 times lower
Carl-David Agardh, 1946-2013.
A Randomized Clinical Trial of Prophylaxis in Children with Hemophilia A (the ESPRIT Study).
Background: Prevention of arthropathy is a major goal of hemophilia treatment. While studies in adults have demonstrated an impact of prophylaxis on the incidence of joint bleeds and patients' well-being in terms of improved quality of life (QoL), it is unclear whether or not prophylaxis influences the outcome and well-being perception of children with hemophilia. Objective: This randomized contro
Intraoperative Hydroxyethyl Starch and its Effects on Different Fibrinogen Measurements.
Intravenous fluids with synthetic colloids such as hydroxyethyl starch (HES) are known to interfere with plasma fibrinogen concentration measurements. The aim of this study was to evaluate the effects of an HES solution on fibrinogen measurements in a clinical setting.
The role of the meniscus in osteoarthritis genesis.
The history of treating meniscal lesions has been characterized by firm belief in "radical" surgery, with serious long-term consequences for the individual and society. The menisci play a critical protective role for the knee joint through shock absorption and load distribution. Currently, the consensus in surgical treatment of meniscal tears is to preserve as much functional meniscal tissue as po
Global response of terrestrial ecosystem structure and function to CO2 and climate change: results from six dynamic global vegetation models
Effect of bioactive polypeptides on leaking large bowel anastomosis and intestines in the rat.
Anastomotic leakage and postoperative adhesions represent major complications after colorectal surgery. We have previously shown a positive effect on both anastomotic strength and abdominal adhesions by the use of differently charged bioactive polypeptides. The present study aimed to investigate the effect of the same polypeptides on the healing of an insufficient intestinal anastomosis, as well a
Disc Hemorrhages and Treatment in the Early Manifest Glaucoma Trial.
PURPOSE: To evaluate the effect of intraocular pressure (IOP)-reducing treatment on the development of disc hemorrhages in patients with glaucoma. DESIGN: Prospective cohort study of patients in the Early Manifest Glaucoma Trial, followed up to 11 years (median = 8 years). PARTICIPANTS: Patients with newly detected glaucoma randomized to argon laser trabeculoplasty plus betaxolol (n = 129) or no i
The accuracy of migration distance measures
The spatial dimension in the definition of internal migration usually refers to the distance someone has tomove to be regarded as a migrant. Lack of precise data on migration distances, however, has obliged migration researchers to use aggregate distance measures whose accuracy is largely unknown, raising potentially serious validity concerns for research. The aim of this paper is to examine the a
Postprandial blood glucose response in relation to gastric emptying and satiety in healthy subjects.
Glucostatic appetite regulation has numerous determinants, among others: cephalic phase digestion, gastric emptying and absorption, together influencing postprandial blood glucose responses and satiety. This short communication presents and reviews studies of gastric emptying, antral distension and postprandial glucose response and their relation to reports of satiety in healthy non-obese over nig
