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Metabolic complications are prevalent in individuals treated with cranial radiotherapy (CRT) for childhood acute lymphoblastic leukemia (ALL). The hypothalamus is a master regulator of endocrine and metabolic control. The aim of this study was to investigate whether the hypothalamic volume would be associated to metabolic parameters in ALL survivors. Thirty-eight (21 women) survivors participated
Screening instruments are often used for detecting mental health problems in children and adolescents. The Strengths and Difficulties Questionnaire (SDQ) is one instrument for screening children's mental health. The SDQ can be used for assessment by different informants, i.e. parents, teachers and by 11-16 year olds for self-reporting.
Uncoupling protein 2 (UCP2) is upregulated in the brain after sublethal ischemia, and overexpression of UCP2 is neuroprotective in several models of neurodegenerative disease. We investigated if increased levels of UCP2 diminished neuronal damage after global brain ischemia by subjecting mice overexpressing UCP2 (UCP2/3tg) and wild-type littermates (wt) to a 12-min global ischemia. The histopathol
Fuel economy and emissions are the two central parameters in heavy duty engines; most of the existing heavy duty engines are run with diesel. The overall efficiency of diesel engines is good however they suffer from high levels of emissions mainly NOX and soot. Using alternative fuels like Natural-Gas has shown to be a good way to reduce emissions level. Diesel engines can be easily converted to N
Artikel om den amerikanska pornografiforskningen och kontrasten mellan de amerikanska feministerna som är pro-pornografi och den svenska feminismens demonisering av pornografin. Med anledning av Milos Formans film Larry Flynt - skandalernas man (The People vs Larry Flynt)
An analytical procedure is presented for generating the computational distribution for the Zigangirov-Jelinek stack algorithm. Multitype branching processes are employed to develop a procedure for estimating sequential decoding computation, without the need for simulation, but with sufficient accuracy to be a valid design tool. At information rates about the cutoff rateR_{o}the calculated computat
Vilka utmaningar skapar den globala rättviserörelsen för äldre och nyare teorier om sociala rörelser? I denna text diskuteras dels traditionella teorier som Marx och Sombarts, dels teorierna om "nya sociala rörelser" (Touraine med flera). Denna diskussion kompletteras med presentationen av data från en enkätundersökning gjord vid lokala sociala forum i Sverige.
This article summarises the ultrasound features of a number of gynaecological emergencies: ectopic pregnancy, haemorrhagic corpus luteum, twisted adnexa, pelvic inflammatory disease, acute myoma necrosis, haematocolpos and haematometra. The basis of all diagnosis in women with acute gynaecological conditions is history and clinical examination. An ultrasound examination should only be performed if
The transforming growth factor (TGF)-beta superfamily of growth factors, including the TGF-betas, activins, and bone morphogenetic proteins (BMPs), provide cells with a broad spectrum of regulatory signals through the intracellular Smad pathway. Since loss-of-function studies of a majority of the TGF-beta superfamily members result in embryonic lethality, much of our current knowledge of the TGF-b
Popular Abstract in Swedish Trådlös kommunikation via radiosystem har närapå blivit en rättighet i dagens samhälle. Vi förväntar oss att internet inte ska vara mer fjärran än där vi senast lade vår ``smarta mobiltelefon''; antagligen inom armlängds avstånd. Strömmning av data ökar ständigt då vi nuförtiden själva vill bestämma när och var vi ska avnjuta, till exempel senaste säsongen i favoritseRadio systems, along with the ever increasing processing power provided by computer technology, have altered many aspects of our society over the last century. Various gadgets and integrated electronics are found everywhere nowadays; many of these were science-fiction only a few decades ago. Most apparent is perhaps your ``smart phone'', possibly kept within arm's reach wherever you go, that prov
The classification of diseases has several important applications ranging from diagnosis and choice of treatment to demographics. To date, classifications have been successfully created manually, often within international consortia. Some groups of diseases, such as primary immunodeficiencies (PIDs), are especially hard to nosologically cluster due, on one hand, to the presence of a wide variety o
To determine whether expression patterns of segmentation genes found in Drosophila melanogaster can be scaled to pattern larger insects, we studied the expression of the Krüppel (Kr) gene in the blowfly Lucilia sericata. Compared with Drosophila Kr, L. sericata Kr showed an unexpected 10% shift of expression towards the anterior pole. Furthermore, expression domains not found in D. melanogaster we
