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Effectiveness of JAK Inhibitors Compared With Biologic Disease-Modifying Antirheumatic Drugs on Pain Reduction in Rheumatoid Arthritis : Results From a Nationwide Swedish Cohort Study

Objective: To compare the effectiveness of JAK inhibitors (JAKis) and biologic disease-modifying antirheumatic drugs (bDMARDs) on pain in patients with rheumatoid arthritis. Methods: In this retrospective study, we investigated patients with a diagnosis of rheumatoid arthritis, starting treatment with a JAKi (n = 1,827), a tumor necrosis factor inhibitor (TNFi; n = 6,422), an interleukin-6 inhibit

High Resolution ISAR Imaging Methods for RCS Data Analysis

Radar Cross Section measurement data is often analyzed using Inverse Synthetic Aperture Radar images. Backprojection is the conventional method to create these images but is limited in resolution. This paper builds on developments of ℓ1-minimization and iterative smooth reweighted ℓ1-minimization to get superresolution and adding another processing step with Gaussian smoothing. This step improves

Mapping the impact of malnutrition as defined by the Global Leadership Initiative on Malnutrition and nutrition impact symptoms on the possibility of returning to work after treatment for head and neck cancer

Purpose: This study aimed to investigate whether malnutrition or nutrition impact symptoms (NIS) affect the possibility of returning to work after treatment for head and neck cancer. Methods: Patients of working age with head and neck cancer were followed up from treatment initiation to 3 months (n = 238), 1 year (n = 182), and 2 years (n = 130) after treatment completion. The observed decrease in

Early Detection of Forest Bark Beetle Attack Using Time Series Spatial Variability of Spectral Indexes from Sentinel-2

Bark beetle infestations pose a significant threat to forest ecosystems, necessitating timely intervention for effective management and conservation. This study focuses on an 8,100 km2 area in southern Sweden, heavily impacted by a bark beetle outbreak triggered by a severe drought in 2018. Using spectral indices derived from Sentinel-2 data, it explores the potential of a window-based approach fo

Is Gen Z a pro-SDG generation? A critical review and reflection

Generation Z (Gen Z) will soon become the biggest living generation and the most dominant in terms of population and economic power, making them one of the tourism industry’s fastest-growing segments and a crucial market to target. There is growing evidence that Gen Z is concerned about the environmental and social effects of their consumption and is guided by strong ethical and environmental idea

Music and reading activities in early childhood associated with improved language development in preterm infants at 2–3 years of age

Introduction: Children born preterm are at increased risk for adverse neurodevelopmental outcomes. Music and reading activities in childhood could ameliorate these difficulties, as they have shown benefits on both neural and behavioral levels. However, only a few studies have assessed these potential benefits in preterm-born children. We investigated whether music and language activities in early

Ductus venosus opens in high-risk pregnancies without signs of increased central venous pressure

Objectives: It has been belived that changes in diastolic blood velocities in the fetal ductus venosus were due to increased central venous pressure secondary to increased fetal heart strain during hypoxia or heart failure. There have been recent reports of changes in ductus venosus blood velocity without signs of increased fetal heart strain. The aim of this evaluation was to compare blood veloci

BeBOP-Combining Reactive Planning and Bayesian Optimization to Solve Robotic Manipulation Tasks

Robotic systems for manipulation tasks are increasingly expected to be easy to configure for new tasks. While in the past, robot programs were often written statically and tuned manually, the current, faster transition times call for robust, modular and interpretable solutions that also allow a robotic system to learn how to perform a task. We propose the method Behavior-based Bayesian Optimizatio

18 F-FDG-PET/CT in breast cancer imaging : Restaging and Implications for treatment decisions in a clinical practice setting

Background and purpose: Although the diagnostic accuracy of 18F-fluorodeoxyglucose – positron emission tomography/computed tomography (18F-FDG-PET/CT) for breast cancer (BC) has been well studied, few studies have evaluated the impact of 18F-FDG-PET/CT on BC patient care. This study aimed to investigate restaging and 18F-FDG-PET/CT-induced changes in clinical decision-making in patients with BC. M

Facilitating accessible, rapid, and appropriate processing of ancient metagenomic data with AMDirT

Background: Access to sample-level metadata is important when selecting public metagenomic sequencing datasets for reuse in new biological analyses. The Standards, Precautions, and Advances in Ancient Metagenomics community (SPAAM, https://spaam-community.org) has previously published AncientMetagenomeDir, a collection of curated and standardised sample metadata tables for metagenomic and microbia

Faithful graphical representations of local independence

Graphical models use graphs to represent conditional independence structure in the distribution of a random vector. In stochastic processes, graphs may represent so-called local independence or conditional Granger causality. Under some regularity conditions, a local independence graph implies a set of independences using a graphical criterion known as δ-separation, or using its generalization, µ-s

Machine learning-derived asthma and allergy trajectories in children : a systematic review and meta-analysis

INTRODUCTION: Numerous studies have characterised trajectories of asthma and allergy in children using machine learning, but with different techniques and mixed findings. The present work aimed to summarise the evidence and critically appraise the methodology.METHODS: 10 databases were searched. Screening, data extraction and quality assessment were performed in pairs. Trajectory characteristics w

Bokslutet från början : Fakta och övningsbok

Bokslutet från början är en kombinerad fakta- och övningsbok som är en direkt fortsättning på grundboken i bokföring, Bokföring från början. I denna bok fördjupas kunskaperna.Steg för steg behandlas de olika områden man måste behärska för att kunna upprätta ett fullständigt bokslut med årsredovisning i enlighet med årsredovisningslagens krav och Bokföringsnämndens allmänna råd. För varje moment fi

Bokslutet från början : Lösningar

Bokslutet från början Lösningar är ett facit med fullständiga lösningar till Bokslutet från början Fakta- och övningsbok.Bokslutet från början är en kombinerad fakta- och övningsbok som är en direkt fortsättning på grundboken i bokföring Bokföring från början. I denna bok fördjupas kunskaperna.Steg för steg behandlas de olika områden man måste behärska för att kunna upprätta ett fullständigt boksl

Platinum-Tin Surface Alloys Studied during O2 Exposure and CO Oxidation Using Grazing Incidence XANES

Platinum-tin catalysts have been used industrially for decades, but their structural evolution under reaction conditions and the causes of their improved activity relative to platinum are still not well understood. In this study, we investigate Sn/Pt(111) and Sn/Pt(223) surface alloys during oxygen exposure and catalytic CO oxidation using grazing incidence X-ray absorption spectroscopy (GI-XAS).

Photoinduced charge transfer renormalization in NiO

Photodoped states in strongly correlated charge-Transfer insulators are characterized by d-d and d-p interactions and the resulting intertwined dynamics of charge excitations and local multiplets. Here, we use femtosecond x-ray absorption spectroscopy in combination with dynamical mean-field theory to disentangle these contributions in NiO. Upon resonant optical excitation across the charge-Transf

Influence of Scanning Strategy on Residual Stresses in Laser-Based Powder Bed Fusion Manufactured Alloy 718 : Modeling and Experiments

In additive manufacturing, the presence of residual stresses in produced parts is a well-recognized phenomenon. These residual stresses not only elevate the risk of crack formation but also impose limitations on in-service performance. Moreover, it can distort printed parts if released, or in the worst case even cause a build to fail due to collision with the powder scraper. This study introduces