Acute cellular rejection (ACR) is a leading cause of graft loss and death after heart transplantation despite effective immunosuppressive therapies. The identification of factors that impair graft vascular barrier function or promote immune cell recruitment during ACR could provide new therapeutic opportunities for the treatment of patients who receive transplants. In 2 ACR cohorts, we found the e

Behovet av att ersätta konventionell fossilbaserad plast blir allt viktigare. Eftersom klimatförändringarna mer synligt påverkar vårt samhälle, förvärrar det problemet att använda icke-hållbara resurser för att tillverka plast. Dessutom hamnar dessa långvariga, icke-återvunna avfall i våra hav, vilket skapar ett inneboende miljöföroreningsproblem. Att forska om nya biobaserade byggstenar för att mThe need to replace conventional fossil-based plastics is becoming more imperative. As climate change is more visibly affecting our society, employing non-sustainable resources to produce plastics is aggravating the problem. Moreover, these long-lasting, non-recycled wastes end up in our oceans, creating an intrinsic environmental pollution problem. Researching new biobased building blocks to enab

Due to desirable optical properties, such as efficient luminescence and large Stokes shift, DNA-templated silver nanoclusters (DNA-AgNCs) have received significant attention over the past decade. Nevertheless, the excited-state dynamics of these systems are poorly understood, as studies of the processes ultimately leading to a fluorescent state are scarce. Here we investigate the early time relaxa

Background: Insulin resistance has been shown to be related to a higher risk of several cancers, but the association with prostate cancer (PCa) has been inconsistent. Methods: We investigated prediagnostic markers of insulin resistance in men in four cohorts in Sweden, in relation to PCa risk (total, non-aggressive and aggressive) and PCa death using multivariable-adjusted Cox regression. The numb

This article is about territorial claims, authority and rights in an urban settlement or ‘bosti’ in central Dhaka. It highlights the drama of a violent encounter between a police officer and a young man, unfolding how the social ordering of urban space is (re)produced in and through authority and violence. It illustrates how situated practices of authority define who can access institutions of rig

We investigate the tetragonal phase of the binary transition metal oxide CuO (t-CuO) within the context of cellular dynamical mean-field theory. Due to its strong antiferromagnetic correlations and simple structure, analysing the physics of t-CuO is of high interest as it may pave the way towards a more complete understanding of high-temperature superconductivity in hole-doped antiferromagnets. In

This article contributes to scholarly discussions about sanctuary enactments. We analyse transversal sanctuary enactments, i.e. when migrants in search of protection are provided with basic welfare and an opportunity to remain, in contestation of the state’s migration politics. The study draws on empirical data collected through a transdisciplinary research initiative in Sweden, the Asylum Commiss

There is an increasing body of evidence, based on well-controlled clinical trials and long-term follow-up, that liposuction can result in significant objective and subjective benefit to patients who have long-term chronic primary or secondary lymphedema. There are, however, different views on the immediate, short-, and long-term benefits of liposuction for treating lymphedema, with a strong dichot

BACKGROUND: The melanoma-specific survival (MSS) is heterogenous between stages and is highly dependent on the T stage for primary localized disease. New systemic therapies for metastatic cutaneous melanoma (CM) have been introduced since 2012 in Sweden.OBJECTIVES: To analyse the incidence and MSS time trends between 1990 and 2020 in Sweden.METHODS: Nationwide, population-based, and prospectively

An emissions barrier was installed in a building where a wall had been treated with a tar-containing material as an impregnation agent and moisture barrier. There was a strong disturbing smell inside the building. Several polycyclic aromatic hydrocarbons (PAH) were identified in the indoor air amounting to a total of 1726 ng PAH/m3. The amounts decreased to 139 ng/m3 after the barrier had been ins

Degenerative meniscus lesions have been associated with both osteoarthritis etiology and its progression. We, therefore, sought to establish a human meniscus ex vivo model to study the meniscal response to cytokine treatment using a proteomics approach. Lateral menisci were obtained from five knee-healthy donors. The meniscal body was cut into vertical slices and further divided into an inner (ava

Many deltas are increasingly threatened by environmental change, including climate change-induced sea-level rise, land subsidence and reduced sediment delivery. Dealing with these challenges is a pressing necessity because deltas are home to many people and are important centres for economic and agricultural development. Successfully adapting to climate change requires a social-ecological system (

An emissions barrier consisting of a cloth with a hydrophilic polymer layer and an adsorbent layer was found to be efficient in stopping radon emissions from radium-containing aerated concrete. Laboratory studies revealed a radon permeability of k= 3.958 x 10-11 m2/s. Applying the cloth indoors in an apartment, on the floor and three walls made up from aerated concrete, resulted in a decrease in i

Objectives: In this study, we apply a clustering method to proteomic data sets from bovine and human models of post-traumatic osteoarthritis (PTOA) to distinguish clusters of proteins based on their kinetics of release from cartilage and examined these groups for PTOA biomarker candidates. We then quantified the effects of dexamethasone (Dex) on the kinetics of release of the cartilage media prote

Saving peak powers in the heating systems have been in focus for some years now. Sweden has more and more cooling systems with an increase in cooling also in residential buildings. The cooling power is much more expensive than the heating power and the cost of cooling is largely driven by installed power. Therefore, there is a relative advantage of reducing the cooling power instead of heating pow