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Background: Airway hyperresponsiveness is a hallmark of asthma across asthma phenotypes. Airway hyperresponsiveness to mannitol specifically relates to mast cell infiltration of the airways, suggesting inhaled corticosteroids to be effective in reducing the response to mannitol, despite low levels of type 2 inflammation. Objective: We sought to investigate the relationship between airway hyperresp

Background: Research on eldercare has been dominated by a provider-oriented perspective, concerned with the conditions and views of care providers. There are striking differences compared with the field of disability studies, where help is framed as part of a larger project of having a daily life and being included in society. Pilot interviews indicate that older people develop active strategies t

Introduction: The striped ambrosia beetle Trypodendron lineatum (Coleoptera, Curculionidae, Scolytinae) is a major forest pest in the Holarctic region. It uses an aggregation pheromone and host and non-host volatiles to locate suitable host trees, primarily stressed or dying conifer trees. The beetles bore into the xylem and inoculate spores of their obligate fungal mutualist Phialophoropsis ferru

Compression of paperboard is a common procedure during industrial package forming and better knowledge of the material response is needed to avoid defective packages and waste. To go beyond current modelling approaches, experimental identification of mechanisms underlying the macroscopic stress–strain responses is needed. In this study, in-situ uniaxial compression of paperboard is studied through

Osteoarthritis (OA) is a chronic joint disease caused by disruption of joint homeostasis by a variety of systemic and biomechanical factors. The disease is characterized by degradation of cartilage and other joint tissues, and low-grade inflammation which may result in pain, reduced function, and disability. The disease appears to have ancient origins, with findings of OA recognized in fossilized

Context: The European Association of Urology (EAU) guidelines panel on upper urinary tract urothelial carcinoma (UTUC) has updated the guidelines to aid clinicians in evidence-based management of UTUC. Objective: To provide an overview of the EAU guidelines on UTUC as an aid to clinicians. Evidence acquisition: The recommendations provided in these guidelines are based on a review of the literatur

We consider a multiqubit system of atoms or ions with two computational ground states and an interacting excited state in the so-called blockade regime, such that only one qubit can be excited at any one time. Examples of such systems are rare-earth-ion-doped crystals and neutral atoms trapped in tweezer arrays. We present a simple laser excitation protocol that yields a complex phase factor on an

Hexagonal YMnO3 is a prototype antiferromagnet which exhibits multiferroic behavior with the ferroelectric and magnetic transitions occurring at different temperatures. We observe an out-of-plane canting of the Mn3+ magnetic moments using resonant x-ray diffraction (RXD) in a single crystal of this material. These canted moments result in the symmetry-forbidden (0,0,1) magnetic Bragg reflection, w

BackgroundThe modified Telephone Interview for Cognitive Status (TICS-M) is a widely used tool for assessing global cognitive functions and screening for cognitive impairments. The tool was conceptualised to capture various cognitive domains, but the validity of such domains has not been investigated against comprehensive neuropsychological assessments tools. Therefore, this study aimed to explore

Networks of coupled dynamical units give rise to collective dynamics such as the synchronization of oscillators or neurons in the brain. The ability of the network to adapt coupling strengths between units in accordance with their activity arises naturally in a variety of contexts, including neural plasticity in the brain, and adds an additional layer of complexity: the dynamics on the nodes influ

Halide perovskites belong to an important family of semiconducting materials with electronic properties that enable a myriad of applications, especially in photovoltaics and optoelectronics. Their optical properties, including photoluminescence quantum yield, are affected and notably enhanced at crystal imperfections where the symmetry is broken and the density of states increases. These lattice d

Sänk skatten på arbete, inför enhetlig moms och rak kapitalbeskattning. Det föreslår nationalekonomen Åsa Hansson i en ny SNS-rapport. Mycket har förändrats sedan den stora skattereformen 1990–91. Om skattesystemet görs om utifrån dagens förutsättningar kan Sverige få högre tillväxt och sysselsättning, menar hon.