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Realism as a theory of science, in the view of the author of this paper, provides elegant solutions to several puzzles and dilemmas, not only in philosophy, but also to some of the most fundamental theorerical and methodological problems in social science. This paper introduces scien­tific realism, and presents one way of applying it to social science.

Physical therapy and social interactions between the stroke patient and health-care professionals or relatives facilitate the process of recovery and promote improvement of lost neurological function after stroke. These observations can be mimicked in an experimental setting by multimodal stimulation provided in the concept of enriched environment. The enriched environment is a housing condition f

GABA (γ-aminobutyric acid) is the major inhibitory neurotransmitter in the central nervous system, and changes in GABAergic neurotransmission modulate the activity of neuronal networks. Gephyrin is a scaffold protein responsible for the traffic and synaptic anchoring of GABAA receptors (GABAAR); therefore, changes in gephyrin expression and oligomerization may affect the activity of GABAergic syna

Physical therapy and social interactions between the stroke patient and health care professionals or relatives facilitate the process of recovery and promote the improvement of neurological function after stroke. These observations can be mimicked in the experimental setting with the concept of enriched environment. The enriched environment is a housing condition for rodents combining social inter

Temperature disturbances are common in patients with severe traumatic brain injury. The possibility of an adaptive, potentially beneficial role for fever in patients with severe brain trauma has been dismissed, but without good justification. Fever might, in some patients, confer benefit. A cadre of clinicians and scientists met to debate the clinically relevant, but often controversial issue abou

The levels of protein kinase C-γ (PKC-γ) and the calcium/calmodulin-dependent kinase II-α (CaMKII-α) were measured in crude synaptosomal (P2), particulate (P3), and cytosolic (S3) fractions of the neocortex of rats exposed to 1-hour and 2-hour middle cerebral artery occlusion (MCAO) and 2-hour MCAO followed by 2-hour reperfusion. During MCAO, PKC levels increased in P2 and P3 in the most severe is

Inom ramen för Svenska kyrkans forskningsenhets projekt "I vems tjänst?", som är ett teologiskt aktionsforskningsprojekt om kyrka och välfärd, har under 2015 denna rapport arbetats fram för att ge en kunskapsöversiktom fält där kyrka och välfärd kopplas till varandra. Syftet med dennaförberedande undersökning är att bidra till underlag för att formulera frågeställningar och problem mer precist. Ra

The Benguela Upwelling System (BUS), located between 30 and 20°S, is one of the fundamental high-productivity systems of the world ocean. The BUS has previously been studied in terms of primary productivity and ecology over glacial-interglacial timescales; however, the response and coupling with the benthic environment have received little attention. Here, for the first time, we present a high-res

The tumor suppressor protein p53 is implicated in cell cycle arrest and DNA repair as well as in apoptosis. In the CNS, p53 has been associated with neuronal cell death following various insults, including cerebral ischemia. We investigated the expression of p53 messenger RNA and protein, and the messenger RNA expression of the p53-responsive gene p21(WAF1/Cip1), in specific hippocampal regions fo