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Adherence to the EAT-Lancet reference diet and risk of type 2 diabetes, metabolic dysfunction-associated steatotic liver disease, and their co-occurrence

Background and aims: The EAT-Lancet Commission proposed a healthy dietary pattern to prevent diet-related diseases while promoting planetary sustainability, but little is known regarding its associations with type 2 diabetes (T2D) and metabolic dysfunction-associated steatotic liver disease (MASLD), both of which are highly prevalent and frequently co-exist. We aimed to assess association of this

Protocol for development of a checklist and guideline for transparent reporting of cluster analyses (TRoCA)

Introduction Cluster analysis, a machine learning-based and data-driven technique for identifying groups in data, has demonstrated its potential in a wide range of contexts. However, critical appraisal and reproducibility are often limited by insufficient reporting, ultimately hampering the interpretation and trust of key stakeholders. The present paper describes the protocol that will guide the d

Detailed numerical simulation of ammonia/diesel combustion under CI engine conditions

Ammonia is considered a promising carbon-free fuel for marine engines, yet challenges persist in utilizing ammonia as a carbon-free marine fuel due to its inherently low reactivity and significant emissions of NOx and N2O. To address these issues, advanced combustion strategies, such as ammonia/diesel dual-fuel Reactivity-Controlled Compression Ignition (RCCI), have been proposed. This thesis pres

Investigating Achilles tendon adaptation to mechanical load : a computational model integrating collagen fibre orientation heterogeneity

Tendons are known to adapt their structural and mechanical properties in response to mechanical loading, but the precise mechanisms underlying this adaptation remain poorly understood. A previous study on rat Achilles tendons compared the effect of unloading (Botox injections and orthosis) with free cage activity (full loading) and revealed that unloading impaired the mechanical response and resul

ECG-based beat-to-beat assessment of AV node conduction properties during AF

Introduction: The refractory period and conduction delay of the atrioventricular (AV) node play a crucial role in regulating the heart rate during atrial fibrillation (AF). Beat-to-beat variations in these properties are known to be induced by the autonomic nervous system (ANS) but have previously not been assessable during AF. Assessing these could provide novel information for improved diagnosis

Internet connectedness of older adults in the time of COVID-19

What happens if we are forced to stay at home over weeks or months? If we are not allowed to see our friends and family members in person?This sounds like a cruel “social experiment,” yet, the world-wide COVID-19 pandemic confronts us with exactly this unimaginable scenario.

Carrying Stories across Borders

This is a short recorded open lecture about the different relations between migration and media, introducing the concept of 'migratory self-adaptation', having two authors and their artistic creation as examples: Marjane Satrapi and Atiq Rahimi. This lecture was a part of "Media Impact" webinars; a series of media production by Linnaeus University Center for Intermedial and Multimodal Studies,

Accelerating aqueous electrolyte design with automated full-cell battery experimentation and Bayesian optimization

The integration of automation and data-driven methodologies offers a promising approach to accelerating materials discovery in energy storage research. Thus far, in battery research, coin-cell assembly has advanced to become nearly fully automated but remains largely disconnected from data-driven methods. To bridge the disconnect, this work presents a self-driving laboratory framework to accelerat

Validity and reliability of the Japanese version of the occupational balance questionnaire

Introduction: Occupational balance, a foundational concept in occupational therapy and science, plays a critical role in enhancing health and well-being. Recent studies have revealed its association with epidemiological factors. This study evaluated the validity and reliability of the Japanese version of the Occupational Balance Questionnaire 11 (OBQ11-J). Methods: Adhering to the COnsensus-based

Genomics of stroke recovery and outcome

The understanding of genomics has improved tremendously during the last decades. The concept of recovery and outcome after stroke has also progressed during this time. However, the connection between genomics and stroke recovery has only begun to emerge in a more structural and comprehensive way. Different types of outcomes and recovery occur after stroke. This depends on domain of neurological de

Thyroid peroxidase antibodies and their role in predicting outcomes in Graves’ disease treatment

Introduction: Graves´ disease (GD) is the predominant cause of hyperthyroidism. Treatment options include antithyroid drugs (ATD), surgery, and radioactive iodine ablation (RI). Although thyroid peroxidase antibodies (anti-TPO) are prevalent in patients with GD, their role in driving relapse or hypothyroidism after treatment in patients with GD remains unclear. This study aimed to determine if pat

Investigating choice awareness through cognitive semiotics

Physicalist approaches to cognition view behaviour as driven by neural mechanisms and automatic processes, often neglecting the complexity of human experience. Cognitive semiotics, rooted in phenomenology, emphasizes consciousness and meaning-making. Central to this is phenomenological triangulation, exploring phenomena through first-, second-, and third-person perspectives. This chapter applies t

A Wideband Distributed Massive MIMO Channel Sounder for Communication and Sensing

Channel sounding is a vital step in the design and deployment of wireless communication systems. In this article, we present the design and implementation of a coherent distributed massive multiple-input-multiple-output (MIMO) channel sounder operating at 5 and 6GHz with a bandwidth of 400MHz based on the NI USRP X410. Through the integration of multiple transceiver chains and radio frequency (RF)

Management of hepatitis B virus (HBV) infection in multiple sclerosis patients on disease modifying therapies (DMTs)

Disease-modifying therapies (DMTs) for multiple sclerosis (MS) can increase the risk of hepatitis B virus (HBV) reactivation (HBr), particularly with agents like ocrelizumab and alemtuzumab. However, studies in MS patients treated with DMTs indicate significantly lower reactivation rates compared to those with hematologic malignancies. This review discusses strategies for managing HBV in MS patien

A Swedish cost-utility analysis of ferric derisomaltose versus ferric carboxymaltose in the treatment of iron deficiency anemia in patients with inflammatory bowel disease

Objectives: Iron deficiency anemia (IDA) is a common extraintestinal manifestation of inflammatory bowel disease (IBD), driven by impaired iron absorption, inflammation of intestinal mucosa and blood loss due to intestinal bleeding. Exogenous iron is indicated to correct iron deficiency, with intravenous iron preferred in patients with malabsorption or intolerance of oral iron, active bleeding, sy