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Metoder för kausal inferens i icke-randomiserade studier (III): : regressionsdiskontinuitetsdesigner
Metoder för kausal inferens i observationsstudier (I): : Instrumentvariabelmetoden
Islet cell cytoplasmic and cell surface antibodies in diabetes mellitus
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Betydelser av etnicitet i vardagen på särskilda ungdomshem
Tillvaron på ett särskilt ungdomshem är speciell på många vis samtidigt som institutionsvardagen i stor grad speglar samhället i övrigt. Eftersom ungdomar och personal kommer nära inpå varandra under längre tid kan frågor om identitet och tillhörighet få extra stor betydelse i det sociala samspelet.I boken undersöks hur etnicitet visas upp, debatteras, skojas om eller används som ett retoriskt ver
Drug Resistance in HIV-Positive Adults During the Initial Year of Antiretroviral Treatment at Ethiopian Health Centers
BACKGROUND: The increasing prevalence of antiretroviral drug resistance in Sub-Saharan Africa threatens the success of HIV programs. We have characterized patterns of drug resistance mutations (DRMs) during the initial year of antiretroviral treatment (ART) in HIV-positive adults receiving care at Ethiopian health centers and investigated the impact of tuberculosis on DRM acquisition.METHODS: Part
Sensitive Stuff and Expressive Caution: Notes on the Research Process in Studies of Ethnicities Associated with Crime
Questions related to crime and migration are delicate matters, potentially because of associations with ethnicity, racism and oppressive politics and ideology in both the past and the present. The delicate nature of issues of crime and deviance may result in expressive caution exercised by both researchers and those studied. In this article, we discuss these dynamics in the research process in ter
In vitro digestibility and Caco-2 cell bioavailability of sea lettuce (Ulva fenestrata) proteins extracted using pH-shift processing
Seaweed is a promising sustainable source of vegan protein as its farming does not require arable land, pesticides/insecticides, nor freshwater supply. However, to be explored as a novel protein source the content and nutritional quality of protein in seaweed need to be improved. We assessed the influence of pH-shift processing on protein degree of hydrolysis (%DH), protein/peptide size distributi
A LCMS Metabolomic Workflow to Investigate Metabolic Patterns in Human Intestinal Cells Exposed to Hydrolyzed Crab Waste Materials
We have developed a LCMS metabolomic workflow to investigate metabolic patterns from human intestinal cells treated with simulated gastrointestinal-digested hydrolyzed crab waste materials. This workflow facilitates smart and reproducible comparisons of cell cultures exposed to different treatments. In this case the variable was the hydrolysis methods, also accounting for the GI digestion giving a
Enhanced Protocatechuic Acid Production From Glucose Using Pseudomonas putida 3-Dehydroshikimate Dehydratase Expressed in a Phenylalanine-Overproducing Mutant of Escherichia coli
Protocatechuic acid (PCA) is a strong antioxidant and is also a potential platform for polymer building blocks like vanillic acid, vanillin, muconic acid, and adipic acid. This report presents a study on PCA production from glucose via the shikimate pathway precursor 3-dehydroshikimate by heterologous expression of a gene encoding 3-dehydroshikimate dehydratase in Escherichia coli. The phenylalani
Propionic acid production from glycerol in immobilized cell bioreactor using an acid-tolerant strain of Propionibacterium acidipropionici obtained by adaptive evolution
Propionic acid (PA) production from agro-industrial residues using propionibacteria has gained interest as an alternative to fossil-based process. Microbial production is however characterized by product inhibition, lowering the product titers and productivity. In this study, Propionibacterium acidipropionici DSMZ4900 was subjected to adaptive evolution to tolerate higher acid concentrations. The
Photoelectrochemical oxidation in ambient conditions using earth-abundant hematite anode : A green route for the synthesis of biobased polymer building blocks
This study demonstrates the use of a photoelectrochemical device comprising earth-abundant hematite photoanode for the oxidation of 5-hydroxymethylfurfural (5-HMF), a versatile bio-based platform chemical, under ambient conditions in the presence of an electron mediator. The results obtained in this study showed that the hematite photoanode, upon doping with fluorine, can oxidize water even at low
Hypoxia Generated by Avian Embryo Growth Induces the HIF-α Response and Critical Vascularization
Cancer research has transformed our view on cellular mechanisms for oxygen sensing. It has been documented that these mechanisms are important for maintaining animal tissues and life in environments where oxygen (O2) concentrations fluctuate. In adult animals, oxygen sensing is governed by the Hypoxia Inducible Factors (HIFs) that are stabilized at low oxygen concentrations (hypoxia). However, the
RENEB/EURADOS field exercise 2019 : robust dose estimation under outdoor conditions based on the dicentric chromosome assay
Purpose: Biological and/or physical assays for retrospective dosimetry are valuable tools to recover the exposure situation and to aid medical decision making. To further validate and improve such biological and physical assays, in 2019, EURADOS Working Group 10 and RENEB performed a field exercise in Lund, Sweden, to simulate various real-life exposure scenarios. Materials and methods: For the di
Navigating unChartered waters : anchoring Athena SWAN into Irish HEIs
The UK Athena SWAN (AS) Charter was extended to Irish Higher Education Institutions (HEIs) in 2015 to provide a catalyst for change towards gender equality and to transform institutional cultures, through AS Gender Action Plans. This paper charts: the journey of Athena SWAN to Ireland; its rate of adoption by Irish HEIs; and its impact on the sector. Drawing upon the perspective and contribution o
Exploring clinical reasoning in Austrian mental health physiotherapy : the physiotherapist´s perspective
Introduction: In mental health physiotherapy, there is a lack of research investigating the assumptions and clinical reasoning strategies of the professionals. A critical view on what is taken for granted within physiotherapy promotes professional development. Purpose: The purpose of this study was to explore and describe the essence of clinical reasoning of Austrian mental health physiotherapists
Literature review of fungi in buildings and their ability to methylate chlorophenols into malodorous chloroanisoles
A source of indoor malodor in older buildings are chloroanisoles, a methylation from chlorophenols. Chlorophenols were commonly used in wood preservatives 50 years ago which were used to treat construction details exposed to high moisture loads. The methylation process requires a methylator in the form of fungi or bacteria in conjunction with adequate growth conditions for said fungi. The food ind
Robust municipal decision making? A pilot study of applying robust decision making in three Swedish municipalities
The growing understanding of the increased frequency and severity of extreme weather events due to climate change demands action. Locally, measures to adapt must be taken without knowing exactly what will happen, where it will happen or what the consequences will be. To meet this need, a number of decision support tools have been developed and this article investigates how municipalities can imple
Targeted genomic investigations in a population-based cohort of mantle cell lymphoma reveal novel clinically relevant targets
Mantle cell lymphoma (MCL) is an aggressive B-cell neoplasm that follows a heterogeneous clinical course. Recurrent mutations have been described, but their applicability in the clinical setting is currently limited. The main reasons are challenges in the sequencing of DNA retrieved from formalin-fixed tissue commonly used for tissue collection in clinical biobanks. In this study, we sequenced 77