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Characterization of Streptococcal Nucleases and Identification of their Host Interactomes

Streptococcus pneumoniae and Streptococcus pyogenes are Gram-positive bacteria responsible for a wide spectrum of diseases, ranging from mild to even life-threatening. The annual global mortality rates of the bacteria amount to 1.68 million. While vaccines against S. pneumoniae are included in our medical arsenal, their efficacy is limited by poor immune responses in certain age groups or insuffic

Real-Time Geometry Reconstruction with Compute Shader Tessellation

Rendering high-fidelity geometry in real time poses significant challenges due to the large data size, increased computational demands, and memory bandwidth limitations associated with dense meshes. While several techniques have been proposed to address these challenges — such as discrete level-of-detail (LOD) systems, hardware-based tessellation, and virtualized geometry solutions like Nanite. Ho

Factorizing Charm Production in Proton-Proton Collisions with PYTHIA

In this thesis, proton-proton collisions at 7 TeV are simulated using PYTHIA. Charm and anticharm quarks are identified as being produced from direct, meaning that the charm and anticharm are pair produced by a hard scattering, or indirect interactions where the charm and anticharm pair is produced from the splitting of a single gluon. This data is used to generate a pT spectrum and correlation fu

Climate-resilient Urban Neighborhoods: Assessment of Urban Densification Scenarios in the Extreme Climate events

Growing population in Swedish cities and limited natural resources combined with climate change impacts led decision-makers to develop densification strategies in city planning. However, densification could come with several challenges including reduced green spaces, increased urban heat island effect and energy demand, as well as the lack of thermal comfort in buildings. Densification becomes eve

Urban Branding and Talent Migration: The Role of Urban Image in Shaping Migration Decisions

This study explores how urban branding intervenes in the formation and realization of migration aspirations and capabilities among talent migrants, using Chengdu as a case study. Based on the Aspirations–Capabilities framework, this study applies mixed-methods analysis, combining quantitative data analysis, digital ethnography (analyzing government urban branding narratives and post-migrants’ expe

Enhanced Oxidation Resistance of AlCoCrFeNi High Entropy Alloy Obtained by Annealing

High-Entropy Alloys (HEAs) have emerged as a promising class of materials for extreme environments due to their unique compositional complexity and the resultant enhanced thermal stability. Among them, AlCoCrFeNi has garnered significant attention for its superior oxidation resistance at elevated temperatures, primarily owing to the formation of protective alpha alumina (Al₂O₃) surface oxide s

Integration of Solid State Physics in Secondary School Education

The understanding of solid state physics is a significant part of understanding the foundations of modern technology and engineering. Applications of solid state physics are broad; it includes solar panels, laser technology, transistors, light emitting diodes (LEDs), and many more, all of which have been significant technological advancements that have offered people efficient and useful devices a

“Berätta ingenting för mig, för jag orkar inte bry mig om något just nu” En kvalitativ studie om socionomers upplevelser och hantering av empatitrötthet

This study investigates how social workers in human service professions experience and manage compassion fatigue. The focus is on factors that contribute to mental and physical exhaustion, as well as the strategies social workers use to prevent and manage these. The study was based on a qualitative methodological approach, where data collection was based on six semi-structured interviews with qual

Exploring Tumor Modeling and Immunotoxicology - Precision-Cut Tumor Slices of Head and Neck Squamous Cell Carcinoma and Immune Response to Nanoplastics

Head and neck squamous cell carcinoma (HNSCC) is a heterogenous cancer with poor prognosis, especially for patients with advanced or recurrent disease. The complex tumor microenvironment (TME) plays an important role in mediating immune evasion and therapy resistance. To improve preclinical testing, advanced 3D in vitro and ex vivo models such as spheroids, organoids, and tumor slice cultures have

Political Ecology in Spain

An exploration of how writers, artists, and filmmakers expose the costs and contest the assumptions of the Capitalocene era that guides readers through the rapidly developing field of Spanish environmental cultural studies.

Tinkering with Care : Digital Tools and the Struggle to Maintain Meaningful Activities for People with Intellectual Disabilities During COVID-19

The COVID-19 pandemic and the policies introduced to curb its spread exacerbated the vulnerabilities experienced by people with disabilities. Facing laws limiting gatherings and policies closing down services and banning visitors from care and service homes, care providers found themselves needing to find new and alternative ways to engage with and support care users. Seeking to provide adequate cThe COVID-19 pandemic and the policies introduced to curb its spread exacerbated the vulnerabilities experienced by people with disabilities. Facing laws limiting gatherings and policies closing down services and banning visitors from care and service homes, care providers found themselves needing to find new and alternative ways to engage with and support care users. Seeking to provide adequate c

Advanced Descaling Techniques for High-Temperature Oxidation in Stainless-Steel Alloys

The high-temperature oxidation of stainless-steel parts poses significant problems in power generation, chemical processing, and heat exchanger industries. Stainless steel grades such as austenitic AISI 316L, 310S, and ferritic 430 commonly used in industries undergo carving of oxide scales which diminishes spatial quality, increases corrosion, and reduces thermal conductivity. This thesis focuses

Representing and rekindling conviviality : The role of Burgaz islanders’ media productions in resilience, solidarity, and reunion

This article examines how Burgaz islanders use media productions – novels, memoirs, documentaries, and interview-based books – to represent and rekindle conviviality, resilience, and solidarity in response to political crises and forced migration within a post-Ottoman homogenising context. By combining media studies and anthropology, I analyse narratives and representations in these media producti

A decolonial and participatory research approach to envision equitable transformations toward sustainability in the Amazon

How people relate to and see themselves as part of nature relations differs worldwide and often depends on culture and worldviews. Nonetheless, challenging the dominant Euro-Western epistemic domination is needed to attain more equitable and sustainable future visions. This change entails fostering decolonial mediation between different knowledge systems in a context of intersectional difference.

Zero-Shot Pupil Segmentation with SAM 2 : A Case Study of Over 14 Million Images

We explore the transformative potential of SAM 2, a vision foundation model, in advancing gaze estimation. SAM 2 addresses key challenges in gaze estimation by significantly reducing annotation time, simplifying deployment, and enhancing segmentation accuracy. Utilizing its zero-shot capabilities with minimal user input—a single click per video—we tested SAM 2 on over 14 million eye images from a

Letter about a dream

The publication takes the shape of an anthology, and delves into different approaches and methods for sharing the knowledge created through performing arts processes. Through interviews, essays and reflections, it explores, among other things, why sharing knowledge can break down hierarchies and expand the narrrative of what an art practice can be. It asks how we can hold onto lived knowledge and

Gaze behavior in face-to-face interaction : A cross-cultural investigation between Japan and The Netherlands

Previous research suggests a pattern of gaze avoidance in East Asian compared with Western cultures. Yet, recent eye-tracking studies of face-to-face conversation do not corroborate this. More generally, differences in nonverbal communication and analytic versus holistic strategies have been described between East Asian and Western cultures. Using wearable eye-tracking technology and an automated