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Det beräknas att cirka 50 miljoner människor världen över har en demenssjukdom mot förväntade 152 miljoner år 2050 och enligt WHO är demenssjukdomar en prioriterad hälsopolitisk fråga. Primärvårdsläkares roll i upptäckt och behandling av tidig demens är troligen hälsoekonomiskt fördelaktig men primärvårdens handläggning av patienter med förmodad demens varierar stort. Syftet med denna avhandling vBackground: Around 50 million people worldwide have dementia and the prevalence is expected to increase to 152 million by 2050. According to the WHO, dementia is a priority health policy issue. The role of primary care physicians (PCPs) for timely dementia management can be cost-effective, yet PCP involvement in the management of patients with presumed or diagnosed dementia vary across Europe.Aim:

Spectral oscillations in 2D molecular spectroscopy of the displaced oscillator system and their phase relationships are analyzed. The phase maps of the dispersive and absolute-valued signals give hints for experimental probing of peak oscillations.

A variety of two-dimensional electronic spectroscopy experiments on natural lightharvesting complexes reveal inter-chromophore coupling and monitor ultrafast dynamics, furthering understanding of the way these proteins function and the underlying design principles of photosynthesis.

Two-dimensional Fourier transform electronic spectra were recorded for the LH3 light harvesting complex. The spectra reveal the weak coupling between B800 molecules, the ultrafast dynamics within B820 and energy flow from B800 to B850.

Two-dimensional optical spectroscopy is a potent tool for studying correlations among different vibrational and electronic transitions as well as other nonlinear properties of molecules and materials. This chapter utilizes recently developed phase-stabilized two-dimensional electronic Fourier-transform spectroscopy to probe electronic couplings among different chromophores and explore the distribu

This thesis consists of three papers that study individual preferences. The focus of the first two papers is on time preferences. In the third paper, preferences regarding how inequality in health and income should be defined are elicited.In the first paper, we study the long-term stability of survey-based subjective time preferences using a Dutch household survey panel. We find that while the ind

The two-photon absorption (TPA) properties of β-carotene (beta-carotene) in chloroform solution were investigated over the 590-790 nm wavelength range. The TPA was characterized using the open-aperture z-scan technique with picosecond pulses provided by a widely traveling-wave optical parametric amplifier (OPA) pumped with a Ti:sapphire laser amplifier. We found the 0.2-1 cm/GW values of two photo

Attempts to measure the capitalization of local taxes into property prices, starting with Oates (1969), have suffered from a lack of local public service controls. We revisit this vast literature with a novel dataset of 947 time-varying local characteristic and public service controls for all municipalities in Sweden over the 2010-2016 period. To make use of the high dimensional vector of controls

Digital work has become part of social workers’ daily routines in countries where digitalisation is on the agenda. As a consequence, documentation practices are expanding—on paper as well as digitally—and include reporting detailed statistics about client interventions, filling in digital forms, and fulfilling local and national performance measurement goals. Standardised formulas with tick-box an

Femtosecond spectroscopy is an important tool used for tracking rapid photoinduced processes in a variety of materials. To spatially map the processes in a sample would substantially expand the method’s capabilities. This is, however, difficult to achieve, due to the necessity of using low-noise detection and maintaining feasible data acquisition time. Here, we demonstrate realization of an imagin

Arguably among the most globally impactful climate changes in Earth's past million years are the glacial terminations that punctuated the Pleistocene epoch. With the acquisition and analysis of marine and continental records, including ice cores, it is now clear that the Earth's climate was responding profoundly to changes in greenhouse gases that accompanied those glacial terminations. But the u

Palmitoyl-protein thioesterase 1 (PPT1) is a depalmitoylation enzyme that is mutated in cases of neuronal ceroid lipofuscinosis (NCL). The hallmarks of the disease include progressive neurodegeneration and blindness, as well as seizures. In the current study, we identified 62 high-confident PPT1-binding proteins. These proteins included a self-interaction of PPT1, two V-type ATPases, calcium volta