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Improvements of the adiabatic film cooling by using two-Row holes of different geometries and arrangements

Existing researches on two-row film cooling mainly focused on double-jet film cooling. However, researches on the effects by combining different kinds of hole shapes on film cooling performance are quite limited. In order to improve the film cooling effectiveness, the three-dimensional numerical method is utilized to investigate the effects of a novel structure composed of two-row holes with diffe

PET amyloid in normal aging : direct comparison of visual and automatic processing methods

Assessment of amyloid deposits is a critical step for the identification of Alzheimer disease (AD) signature in asymptomatic elders. Whether the different amyloid processing methods impacts on the quality of clinico-radiological correlations is still unclear. We directly compared in 155 elderly controls with extensive neuropsychological testing at baseline and 4.5 years follow-up three approaches:

Expression of HGF, pMet, and pAkt is related to benefit of radiotherapy after breast-conserving surgery : a long-term follow-up of the SweBCG91-RT randomised trial

Experimental studies suggest that hepatocyte growth factor (HGF) and its transmembrane tyrosine kinase receptor, Met, in part also relying on Akt kinase activity, mediate radioresistance. We investigated the importance of these biomarkers for the risk of ipsilateral breast tumour recurrence (IBTR) after adjuvant radiotherapy (RT) in primary breast cancer. HGF, phosphorylated Met (pMet) and phospho

Global biogeography of fungal and bacterial biomass carbon in topsoil

Bacteria and fungi, representing two major soil microorganism groups, play an important role in global nutrient biogeochemistry. Biogeographic patterns of bacterial and fungal biomass are of fundamental importance for mechanistically understanding nutrient cycling. We synthesized 1323 data points of phospholipid fatty acid-derived fungal biomass C (FBC), bacterial biomass C (BBC), and fungi:bacter

The fossil alga Chaetocladus gracilis revisited : new material from the Silurian of Sweden

In 2006, a new species of non-calcified dasycladalean alga, Chaetocladus gracilis, from the upper Silurian of Skåne (Scania), southernmost Sweden, was erected. The original description was based on a single incomplete fossil recovered from the abandoned limestone quarry at Bjärsjölagård, a classic geologic locality in Scania. Here we present four additional and, importantly, more complete specimen

A large strain gradient-enhanced ductile damage model : finite element formulation, experiment and parameter identification

A gradient-enhanced ductile damage model at finite strains is presented, and its parameters are identified so as to match the behaviour of DP800. Within the micromorphic framework, a multi-surface model coupling isotropic Lemaitre-type damage to von Mises plasticity with nonlinear isotropic hardening is developed. In analogy to the effective stress entering the yield criterion, an effective damage

Unexpected differences between surface and bulk spectroscopic and implied Kondo properties of heavy fermion CeRh2Si2

Ultra-violet angle-resolved photoemission spectroscopy (UV-ARPES) was used to explore the temperature dependence of the Ce-4f spectral responses for surface and bulk in the antiferromagnetic Kondo lattice CeRh2Si2. Spectra were taken from Ce- and Si-terminated surfaces in a wide temperature range, and reveal characteristic 4f patterns for weakly (surface) and strongly (bulk) hybridized Ce, respect

A New Beginning : Young Women's Experiences and Sexual Function 18 Months After Bariatric Surgery

Introduction: Female patients expect improved quality of life, including sexual health and regain of fertility after bariatric surgery. Little has been published on to the extent to which patients’ expectations are met by the weight loss after surgery. Aim: To explore how women perceive the effects of bariatric surgery on quality of life, focusing on sexual health and fertility. Methods: A qualita

Poor outcome of patients with pulmonary arterial hypertension with insufficient response to phosphodiesterase-5 inhibitors alone or in combination with other specific therapy : a registry-based study

Phosphodiesterase-5 inhibitors are commonly used in pulmonary arterial hypertension but, as suggested by the RESPITE study, phosphodiesterase-5 inhibitor therapy (mono-/combination) does not always have a satisfactory treatment effect. This study aimed to investigate the clinical course of pulmonary arterial hypertension patients not at treatment goal after at least 90 days of treatment with phosp

Theoretical and Experimental Results for Planning with Learned Binarized Neural Network Transition Models

We study planning problems where the transition function is described by a learned binarized neural network (BNN). Theoretically, we show that feasible planning with a learned BNN model is NP-complete, and present two new constraint programming models of this task as a mathematical optimization problem. Experimentally, we run solvers for constraint programming, weighted partial maximum satisfiabil

Secreted cystatins decrease proliferation and enhance apoptosis of human leukemic cells

Cysteine proteases are implicated in proteolysis events favoring cancer cell growth, spread, and death by apoptosis. Herein, we have studied whether the net growth and survival of the leukemic cell lines Jurkat, U937, and HL-60 are affected by external addition of five proteins acting as natural cysteine protease inhibitors. None of the cystatins examined (A, C, D, and E/M) or chagasin showed cons

Quantitative K-Cl-S chemistry in thermochemical conversion processes using in situ optical diagnostics

The sulfation of gas-phase KOH and KCl was investigated in both oxidizing and reducing atmospheres at temperatures of 1120 K, 1260 K, 1390 K, and 1550 K. Well-defined gas environments were generated in a laminar flame burner fuelled with CH4/air/O2/N2. Atomized K2CO3 and KCl water solution fog and SO2 were introduced into the hot gas as sources of potassium, chlorine, and sulfur, respectively. The

A risk analysis methodology for the use of crowd models during the Covid-19 pandemic

Pandemics such as Covid-19 have posed a set of questions concerning safe space usage given the risk of virus transmission in confined and open spaces. In this context, this report presents a risk analysis methodology for the use of crowd modelling tools as an aid to assess safety in confined and open spaces. Crowd models can be used to investigate people movement in the built environment, thus the