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A case-control study of non-Hodgkin lymphoma and exposure to pesticides

BACKGROUND. The incidence of non-Hodgkin lymphoma (NHL) has increased in most Western countries during the last few decades. Immunodefective conditions are established risk factors. In 1981, the authors reported an increased risk for NHL following exposure to certain pesticides. The current study was designed to further elucidate the importance of phenoxyacetic acids and other pesticides in the et

Analysis of fusion transcripts indicates widespread deregulation of snoRNAs and their host genes in breast cancer

Genomic rearrangements in cancer can join the sequences of two separate genes. Studies of such gene fusion events have mainly focused on identification of fusion proteins from the chimeric transcripts. We have previously investigated how fusions instead can affect the expression of intronic microRNA (miRNA) genes that are encoded within fusion gene partners. Here, we extend our analysis to small n

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More than 40% of Dutch women are not financially independent. Tax incentives for single earning families encourage this dependence. In this essay in the Dutch financial newspaper Sigrid Hemels argues that it does not make sense to keep such incentives in times as ours in which 40% of all marriages ends in divorce and in which we are faced with increased cost and a reduced workforce due to the agei

Image-guided breast biopsy and localisation : recommendations for information to women and referring physicians by the European Society of Breast Imaging

We summarise here the information to be provided to women and referring physicians about percutaneous breast biopsy and lesion localisation under imaging guidance. After explaining why a preoperative diagnosis with a percutaneous biopsy is preferred to surgical biopsy, we illustrate the criteria used by radiologists for choosing the most appropriate combination of device type for sampling and imag

Luminescence and vacuum ultraviolet excitation spectroscopy of samarium doped SrB4O7

Sm2+ and Sm3+ co-doped SrB4O7 could be utilized in several high-level optical devices and fundamental knowledge about the optical behavior of these materials benefits the development of luminescent applications. Herein, we report luminescence and its vacuum ultraviolet (VUV) excitation spectra in samarium doped SrB4O7. Both, Sm2+ and Sm3+ luminescence centers have been examined and distinguished i

Ulla Sjöblom

Artikel om skådespelaren Ulla Sjöblom i digitala Svenskt kvinnobiografiskt lexikon

Vitamin D and inflammation in major depressive disorder

Background: Increased inflammation is reported in Major Depressive Disorder (MDD), which may be more pronounced in suicidal subjects. Vitamin D deficiency may drive this pro-inflammatory state due to vitamin D's anti-inflammatory effects. Methods: We quantified plasma 25-hydroxyvitamin D (25(OH)D) and inflammatory markers interleukin (IL)-6 and tumor necrosis factor (TNF)-α, and other inflammatory

Feminint och maskulint, animat och inanimat, manligt och kvinnligt. Form och semantik i Urshultsmålets nominalsystem

My paper studies the nominal system in a dialect of Småland, spoken in Urshult,as it has been coded and transcribed in a volume by Swea Johansson, a native speaker of this dialect. In this variety, a large portion of the weak feminines, in modern Swedish roughly nouns ending -a, for example penna ’pencil’, instead end in -e, penne ’pencil’. Furthermore, the definite form frequently ends in -na, pe: My paper studies the nominal system in a dialect of Småland, spoken in Urshult,as it has been coded and transcribed in a volume by Swea Johansson, a native speaker of this dialect. In this variety, a large portion of the weak feminines, in modern Swedish roughly nouns ending -a, for example penna ’pencil’, instead end in -e, penne ’pencil’. Furthermore, the definite form frequently ends in -na,

An integrated transcriptomic- and proteomic-based approach to evaluate the human skin sensitization potential of glyphosate and its commercial agrochemical formulations

We investigated the skin sensitization hazard of glyphosate, the surfactant polyethylated tallow amine (POEA) and two commercial glyphosate-containing formulations using different omics-technologies based on a human dendritic cell (DC)-like cell line. First, the GARD™skin assay, investigating changes in the expression of 200 transcripts upon cell exposure to xenobiotics, was used for skin sensitiz

Identifying a task-invariant cognitive reserve network using task potency

Cognitive reserve (CR) is thought to protect against the consequence of age- or disease-related structural brain changes across multiple cognitive domains. The neural basis of CR may therefore comprise a functional network that is actively involved in many different cognitive processes. To investigate the existence of such a “task-invariant” CR network, we measured functional connectivity in a cog

Excitation energy partition in fission

The transformation of an atomic nucleus into two excited fission fragments is modeled as a strongly damped evolution of the nuclear shape. As in previous studies, it is assumed that the division of mass and charge is frozen in at a critical neck radius of c0=2.5fm. In order to also determine the energetics, we follow the system further until scission occurs at a smaller neck radius, at which point

Validation of Health Education Material for Youth: A Step to Ensure Implementation Fidelity in Community-Based Interventions

Health education materials such as flipbooks enhance learning and deliver key messages in a captivating mode. Validation of such materials is crucial to ensuring implementation fidelity. We conducted a study to achieve two objectives: (a) to develop two flipbooks, one each for adolescents and young married women (YMW); (b) to validate the flipbooks using five parameters, namely, content validity,

Birth size and cancer prognosis: a systematic review and meta-analysis

There is an established link between birth parameters and risk of adult-onset cancers. The Developmental Origins of Health and Disease concept provides potential underlying mechanisms for such associations, including intrauterine exposure to endogenous hormones (androgens and estrogens), insulin-like growth factors, etc. However, there is conflicting evidence on the association between birth param

Pitfalls of medication adherence approximation through EHR and pharmacy records : Definitions, data and computation

Background and purpose: Patients’ adherence to medication is a complex, multidimensional phenomenon. Dispensation data and electronic health records are used to approximate medication-taking through refill adherence. In-depth discussions on the adverse effects of data quality and computational differences are rare. The purpose of this article is to evaluate the impact of common pitfalls when compu

The turn to history in international law and the sources doctrine : Critical approaches and methodological imaginaries

Expanding now familiar debates about the impact of the 'historical turn' upon the field of international law, this article considers some of the different ways in which 'turn to history' scholars have confronted the methodological and theoretical tensions arising from the central, yet paradoxical, role occupied by the sources doctrine in international law. We suggest that the anxiety over the sour

Epilepsy in immigrants and Swedish-born : A cohort study of all adults 18 years of age and older in Sweden

Purpose: We aimed to study the association between country of birth and incident epilepsy in several immigrant groups using Swedish-born individuals as referents. Method: The study population included all adults aged 18 years and older in Sweden, living and deceased, 6,690,598 in the first-generation and 6,683,125 in the second-generation sub-study. Epilepsy was defined as having at least one regi

Consumption of Fish and Long-chain n-3 Polyunsaturated Fatty Acids Is Associated With Reduced Risk of Colorectal Cancer in a Large European Cohort

Background & Aims: There is an unclear association between intake of fish and long-chain n-3 polyunsaturated fatty acids (n-3 LC-PUFAs) and colorectal cancer (CRC). We examined the association between fish consumption, dietary and circulating levels of n-3 LC-PUFAs, and ratio of n-6:n-3 LC-PUFA with CRC using data from the European Prospective Investigation into Cancer and Nutrition (EPIC) coh

Effect of Oxygen Therapy on Cardiovascular Outcomes in Relation to Baseline Oxygen Saturation

Objectives: The aim of this study was to determine the effect of supplemental oxygen in patients with myocardial infarction (MI) on the composite of all-cause death, rehospitalization with MI, or heart failure related to baseline oxygen saturation. A secondary objective was to investigate outcomes in patients developing hypoxemia. Background: In the DETO2X-AMI (Determination of the Role of Oxygen