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Background: Hypertrophic cardiomyopathy (HCM) is the most common monogenic cardiac disorder and the leading cause of sudden cardiac death in the young. Although in a majority of HCM cases there are gene mutations coding for sarcomere proteins, the onset for the clinical consequences of these mutations are difficult to predict, as these mutations do not show any clear relationship to the degree of
This paper presents measurements of W±Z production in pp collisions at a center-of-mass energy of 8 TeV. The gauge bosons are reconstructed using their leptonic decay modes into electrons and muons. The data were collected in 2012 by the ATLAS experiment at the Large Hadron Collider and correspond to an integrated luminosity of 20.3 fb-1. The measured inclusive cross section in the detector fiduci
This paper presents a new method of reconstructing the individual charged and neutral hadrons in tau decays with the ATLAS detector. The reconstructed hadrons are used to classify the decay mode and to calculate the visible four-momentum of reconstructed tau candidates, significantly improving the resolution with respect to the calibration in the existing tau reconstruction. The performance of the
A search for Higgs boson production in association with a pair of top quarks (tt¯ H) is performed, where the Higgs boson decays to bb¯, and both top quarks decay hadronically. The data used correspond to an integrated luminosity of 20.3 fb−1 of pp collisions at √s = 8 TeV collected with the ATLAS detector at the Large Hadron Collider. The search selects events with at least six energetic jets and
This article documents the performance of the ATLAS muon identification and reconstruction using the LHC dataset recorded at s=13 TeV in 2015. Using a large sample of J/ ψ→ μμ and Z→ μμ decays from 3.2 fb- 1 of pp collision data, measurements of the reconstruction efficiency, as well as of the momentum scale and resolution, are presented and compared to Monte Carlo simulations. The reconstruction
Distributions of transverse momentum pT ℓℓ and the related angular variable ϕη∗ of Drell–Yan lepton pairs are measured in 20.3fb-1 of proton–proton collisions at √ s = 8 TeV with the ATLAS detector at the LHC. Measurements in electron-pair and muon-pair final states are corrected for detector effects and combined. Compared to previous measurements in proton–proton collisions at √ s = 7 TeV, these
Measurements of charged jet production as a function of centrality are presented for p–Pb collisions recorded at √sNN = 5.02 TeV with the ALICE detector. Centrality classes are determined via the energy deposit in neutron calorimeters at zero degree, close to the beam direction, to minimise dynamical biases of the selection. The corresponding number of participants or binary nucleon–nucleon collis
The production of J/ψ and ψ(2S) was studied with the ALICE detector in Pb-Pb collisions at the LHC. The measurement was performed at forward rapidity (2.5 < y < 4) down to zero transverse momentum (pt) in the dimuon decay channel. Inclusive J/ψ yields were extracted in different centrality classes and the centrality dependence of the average pt is presented. The J/ψ suppression, quantified with th
We present a Bayesian approach to particle identification (PID) within the ALICE experiment. The aim is to more effectively combine the particle identification capabilities of its various detectors. After a brief explanation of the adopted methodology and formalism, the performance of the Bayesian PID approach for charged pions, kaons and protons in the central barrel of ALICE is studied. PID is p
ATLAS has measured two-particle correlations as a function of the relative azimuthal angle, Δφ, and pseudorapidity, Δη, in s=13 and 2.76 TeV pp collisions at the LHC using charged particles measured in the pseudorapidity interval |η|
The momentum-weighted sum of the charges of tracks associated to a jet is sensitive to the charge of the initiating quark or gluon. This paper presents a measurement of the distribution of momentum-weighted sums, called jet charge, in dijet events using 20.3 fb-1 of data recorded with the ATLAS detector at s=8 TeV in pp collisions at the LHC. The jet charge distribution is unfolded to remove disto
Background Little is known about how pharmaceutical companies lobby authorities or experts regarding procurement or the use of vaccines and antivirals. This paper investigates how members of Denmark's pandemic planning committee experienced lobbying efforts by Roche, manufacturer of Tamiflu, the antiviral that was stockpiled before the 2009 A(H1N1) pandemic. Methods Analysis of interviews with six
AIMS:Register data allow for nuanced analyses of heterogeneities between sub-groups which are not observable in other data sources. One heterogeneity for which register data is particularly useful is in identifying unique migration histories of immigrant populations, a group of interest across disciplines. Years since migration is a commonly used measure of integration in studies seeking to unders
The world’s population is ageing at a rapid and increasing rate. This chapter discusses the challenges that developing countries face as a consequence of growing shares of the population above retirement age. The chapter discusses reasons why commonly advanced solutions to the ageing challenge are not likely to help. Increasing migration is discussed as a non-solution, as is fertility increase and
PurposeBy drawing on a detailed case study of the work of tax consultants, the purpose of this paper is to develop a more detailed understanding of the role of ambiguity in professional work, and its relationship to the division of labour in professional service firms (PSFs).Design/methodology/approachThe paper is based on a three-year, longitudinal interpretive case study comprising 42 interviews
