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Simplicity and maximal commutative subalgebras of twisted generalized Weyl algebras

In this paper we prove three theorems about twisted generalized Weyl algebras (TGWAs). First, we show that each non-zero ideal of a TGWA has non-zero intersection with the centralizer of the distinguished subalgebra R. This is analogous to earlier results known to hold for crystalline graded rings. Second, we give necessary and sufficient conditions for the centralizer of R to be commutative (henc

Effects of whey proteins on glycaemia and insulinaemia to an oral glucose load in healthy adults; a dose-response study.

Background/Objectives:Whey proteins have insulinogenic properties and the effect appears to be mediated from a postprandial plasma amino-acid (AA) response. The aim was to study the possible dose-response relationship between whey intake and glycaemic-, insulinaemic- and plasma AA responses.Subjects/Methods:Twelve healthy volunteers participated in the study. They were provided three whey protein

S100A9 as a pharmacological target molecule in inflammation and cancer.

Upon tissue injury and infection both stressed and dying cells can release proteins that normally reside inside the cells. Some of the released proteins become ligands of various cell surface receptors expressed by local cells and such proteins are denoted damage associated molecular patterns (DAMPs). Binding of some DAMPs to certain cell surface receptors induces signals emanating in the producti

Catalytic Cycle of Multicopper Oxidases Studied by Combined Quantum- and Molecular-Mechanical Free-Energy Perturbation Methods.

We have used combined quantum mechanical and molecular mechanical free-energy perturbation methods in combination with explicit solvent simulations to study the reaction mechanism of the multicopper oxidases, in particular, the regeneration of the reduced state from the native intermediate. For 52 putative states of the trinuclear copper cluster, differing in the oxidation states of the copper ion

Search for strong production of supersymmetric particles in final states with missing transverse momentum and at least three b-jets at root s=8 TeV proton-proton collisions with the ATLAS detector

This paper reports the results of a search for strong production of supersymmetric particles in 20.1 fb(-1) of proton-proton collisions at a centre-of-mass energy of 8 TeV using the ATLAS detector at the LHC. The search is performed separately in events with either zero or at least one high-p (T) lepton (electron or muon), large missing transverse momentum, high jet multiplicity and at least three

Failed hypospadias repair: An algorithm for secondary reconstruction using remaining local tissue.

Salvage hypospadias surgery is performed after failed primary reconstruction. Several treatment strategies have been suggested, all with pros and cons. The aim of this study was to evaluate our treatment algorithm for primary hypospadias repair applied to secondary cases in which a salvage procedure is indicated and, most importantly, local tissue is present. The algorithm was applied to 36 consec

A link between GIP and osteopontin in adipose tissue and insulin resistance.

Low grade inflammation in obesity is associated with accumulation of the macrophagederived cytokine osteopontin in adipose tissue and induction of local as well as systemic insulin resistance. Since GIP (glucose-dependent insulinotropic polypeptide) is a strong stimulator of adipogenesis and may play a role in the development of obesity, we explored whether GIP directly would stimulate osteopontin

Measurement-Based Analysis: The Effect of Complementary Antennas and Diversity on Vehicle-to-Vehicle Communication

In vehicle-to-vehicle (V2V) communication systems the antennas are prone to shadowing and the antenna gain is dissimilar even for same antenna elements if mounted at different positions on the car. This paper investigates the impact of antenna placement based on channel measurements performed with four omni-directional antennas mounted on the roof, bumper, windscreen and left-side mirror of the tr

Photocurrent Generation from Thylakoid Membranes on Osmium-Redox-Polymer-Modified Electrodes.

Thylakoid membranes (TMs) are uniquely suited for photosynthesis owing to their distinctive structure and composition. Substantial efforts have been directed towards use of isolated photosynthetic reaction centers (PRCs) for solar energy harvesting, however, few studies investigate the communication between whole TMs and electrode surfaces, due to their complex structure. Here we report on a promi

Food and health: individual, cultural, or scientific matters?

In personalized nutrition, food is a tool for good health, implying an instrumental relationship between food and health. Food receives a secondary value, while health would appear to be a descriptive biological concept. This article gives an introduction to cultural understandings of food and health. The wider definition of food and health is explored in relation to the commonly used scientific a

Implementation of physical coordination training and cognitive behavioural training interventions at cleaning workplaces - secondary analyses of a randomised controlled trial

This study evaluates the implementation of physical coordination training (PCT) and cognitive behavioural training (CBTr) interventions in a randomised controlled trial at nine cleaners' workplaces. Female cleaners (n - 294) were randomised into a PCT, a CBTr or a reference (REF) group. Both 12-week interventions were performed in groups guided by an instructor. Records were kept on intervention d

Consensus Recommendations on Pathologic Changes in the Hippocampus: A Postmortem Multicenter Inter-Rater Study.

There is no consensus on the pathologic conditions or severity implied by the term "hippocampal sclerosis" (HS). In this study, a panel of experienced neuropathologists evaluated inter-rater agreement for pathologic diagnoses in the hippocampus and proposes consensus recommendations on the use of the term "HS." In a group of 251 cases of HS selected from a large autopsy cohort (1,388; 18%), a coor

NMR and NEXAFS Study of Various Graphite Fluorides

Graphite fluorides with different structural types (CyF)(n) (y = 2.5, 2, and 1) and room temperature graphite fluorides were studied by solid state,NMR and NEXAFS. Data extracted from those two techniques are complementary, providing information about the C-F bonding and the hybridization character of the carbon atom valence states. The comparison of data obtained by different methods such as NMR,

Coupled-Cluster Interaction Energies for 200-Atom Host-Guest Systems

We have developed a method to calculate interaction energies of large systems (such as host-guest or even protein-ligand systems) at the local coupled-cluster with singles, doubles, and perturbative triples level, and with extrapolation to the limit of a complete basis set. The method is based on the polarizable multipole interactions with supermolecular pairs molecular fractionation approach, whi