The three-dimensional structure of a bacterial superantigen, Staphylococcus aureus enterotoxin H (SEH), bound to human major histocompatibility complex (MHC) class II (HLA-DR1) has been determined by X-ray crystallography to 2.6 Å resolution (1HXY). The superantigen binds on top of HLA-DR1 in a completely different way from earlier co-crystallized superantigens from S. aureus. SEH interacts with h

The chapter discusses the spatial aspects of the increased globalization of innovation, analysing both the region’s role in influencing the propensity of actors to engage and to play different roles in global innovation networks (GINs). Until now, different concepts such as global value chain (GVC), global production network (GPN) and GIN have been used to explain the increase globalization of inn

Recent literature stresses the increasing importance of global innovation networks as a new mechanism to organize innovation across geographical space. This paper investigates if institutional diversity, defined at the level of the firm, influences firms’ engagement in GINs. Institutional diversity provides knowledge about the institutional context of other countries, increased capabilities to dea

In an emergency or disaster situation, it is likely that a conglomerate of societal resources will respond to various needs. In such a multi-organizational setting, collaboration becomes necessary. Empirical findings suggest that collaboration can be very problematical and this paper argues that a possible explanation can be found in intra-organizational leadership ideals, dysfunctional in a colla

Perturbation problems for operators with embedded eigenvalues are generally challenging since the embedded eigenvalues cannot be separated from the rest of the spectrum. In this paper, we study a perturbation problem for embedded eigenvalues for a magnetic Schrödinger operator, when the underlying domain is a cylinder. The magnetic potential is C2 with an algebraic decay rate as the unbounded vari

A method for interpolation of multicomponent streamer data based on using the local directionality structure is presented. The derivative components are used to estimate a vector field that locally describes the direction with the least variability. Given this vector field, the interpolation can be phrased in terms of the solution of a partial differential equation that describes how energy is tra

The observation of heavy-ion-like behaviour in pp collisions at the LHC suggests that more physics mechanisms are at play than traditionally assumed. The introduction e.g. of quark-gluon plasma or colour rope formation can describe several of the observations, but as of yet there is no established paradigm. In this article we study a few possible modifications to the Pythia event generator, which

The currently available data on the distribution of C2 fracture subtypes is sparse. This study was designed to identify the proportions of the second cervical vertebra (C2) fracture subtypes and to present age and gender specific incidences of subgroups. A dataset of all patients treated between 2002 and 2014 for C2 fractures was extracted from the regional hospital information system. C2 fracture

Cellobiose dehydrogenase (CDH) is a fungal extracellular flavocytochrome capable of direct electron transfer (DET). Unlike other CDHs, the pH optimum for CDHs from Corynascus thermophilus (CtCDH) and Humicola insolens (HiCDH) is close to the human physiological pH in blood (7.4). These are, therefore, interesting candidates for glucose measurements in human blood and the application in enzymatic f

Composite Higgs Models are often constructed including fermionic top partners with a mass around the TeV scale, with the top partners playing the role of stabilizing the Higgs potential and enforcing partial compositeness for the top quark. A class of models of this kind can be formulated in terms of fermionic strongly coupled gauge theories. A common feature they all share is the presence of spec

BACKGROUND: Although sepsis is a major health problem, data on sepsis epidemiology are scarce. The aim of this study was to assess the incidence of sepsis, based on clinical findings in all adult patients treated with intravenous antibiotic in all parts of all hospitals in an entire population.METHODS: This is a retrospective chart review of patients ≥18 years, living in 2 regions in Sweden, who w

We present X-ray source catalogs for the ≈7 Ms exposure of the Chandra Deep Field-South (CDF-S), which covers a total area of 484.2 arcmin2. Utilizing wavdetect for initial source detection and ACIS Extract for photometric extraction and significance assessment, we create a main source catalog containing 1008 sources that are detected in up to three X-ray bands: 0.5-7.0 keV, 0.5-2.0 keV, and 2-7 k

BACKGROUND: Elevated plasma levels of heparin-binding protein (HBP) are associated with risk of organ dysfunction and mortality in sepsis, but little is known about causality and mechanisms of action of HBP. The objective of the present study was to test the hypothesis that HBP is a key mediator of the increased endothelial permeability observed in sepsis and to test potential treatments that inhi

A building for users with functional disorders has been built with the aim of being a low-energy residence, based on the criteria and technology applicable to passive houses. This new application of the passive house concept in a Nordic climate has shown that challenges must be met when producing buildings with a low energy demand while also fulfilling the requirements for a good indoor climate. T

Although, today, jus cogens is a recognized element of international law and international legal discourse alike, many issues of vital importance to a well-functioning jus cogens regime remain unsettled. The current debate centres on the following six questions: (1) What is the source of jus cogens obligations? (2) What is the role of consent in the creation and modification of jus cogens norms? (

Accurate predictions of net ecosystem productivity (NEPc) of forest ecosystems are essential for climate change decisions and requirements in the context of national forest growth and greenhouse gas inventories. However, drivers and underlying mechanisms determining NEPc (e.g., climate and nutrients) are not entirely understood yet, particularly when considering the influence of past periods. Here

Introduction: Thrombin generation tests (TGTs) are considered to give more detailed information of the overall coagulation capability of a patient than clotting-based routine assays. The TGT thrombin generation assay-calibrated automated thrombogram (TGA-CAT) uses both platelet-poor plasma (PPP) and platelet-rich plasma (PRP). Assessing PRP gives more physiological test conditions and is of great

How is it that a group that self-identifies as “religious” and is associated with one of the most dramatic events in the United States during the 1980s could receive almost no attention from religious studies scholars? Furthermore, how is it that the court case in which said group was determined to not qualify as a “religion” has been discussed and challenged by legal scholars while being virtuall