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Cognitive Training for Emotion-Related Impulsivity and Rumination : Protocol for a Pilot Randomized Waitlist-Controlled Trial

Background: Inhibitory deficits are common in psychopathology. Emotion-related impulsivity (ERI) and rumination are general risk factors for psychiatric distress that are similarly associated with dysfunctional inhibition—particularly in affective contexts. A number of cognitive remediation procedures have been developed to improve inhibitory control; however, most remediation programs focus on “c

Impulsive-compulsive behaviours and striatal neuroactivity in mildly parkinsonian rats under D2/3 agonist and L-DOPA treatment

Dopamine replacement therapy for Parkinson's disease can induce impulsive-compulsive behaviours (ICBs). Here we compare the D2/3 agonist ropinirole and L-DOPA, given alone or combined, with regard to their potential to induce ICBs in rats sustaining bilateral striatal injections of 6-hydroxydopamine. Daily treatment with ropinirole (2.5 mg/kg), L-DOPA (24.0 mg/kg), or their combination was given f

Acinetobacter baumannii Clinical Isolates Resist Complement-Mediated Lysis by Inhibiting the Complement Cascade and Improperly Depositing MAC

Introduction: Acinetobacter baumannii is a gram-negative opportunistic bacterium that causes life-threatening infections in immunocompromised hosts. The complement system is a critical mechanism of innate immunity that protects the human body from bacterial infections. Complement activation leads to the deposition of the membrane attack complex (MAC), which can directly lyse gramnegative bacteria.

Nurse-led atrial fibrillation clinics in primary health care : a review of the evidence

Background: Atrial fibrillation (AF) is the most common arrhythmia worldwide and the majority of AF patients are treated in primary care. In order to minimize hospitalizations and visits to emergency departments, nurse-led care was introduced in secondary care and primary health care (PHC). However, even though nurse-led care was initiated in PHC almost a decade ago, and ESC guidelines recommended

Impact of formula protein quantity and source on infant metabolism : serum, urine, and fecal metabolomes of a randomized controlled study

Background: Human milk offers significant health benefits for infants; however, when not feasible, infant formula serves as an alternative. The higher protein content in infant formula is thought to contribute to the distinct metabolic profiles observed in formula-fed infants compared with those fed human milk. Objectives: This study investigates the impact of formula protein quantity and whey pro

Adverse prognosis gene expression patterns in metastatic castration-resistant prostate cancer

Metastatic castration-resistant prostate cancer (mCRPC) is a heterogeneous disease. Several studies have identified transcriptional subtypes of mCRPC, but comprehensive analysis of prognostic gene expression pathways has been limited. Therefore, we aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression-based pathways with clinical out

Predicting Reduction Potentials of Blue Copper Proteins Using Quantum Mechanical Calculations

We have calculated redox potentials of 12 blue copper protein sites comparing 64 computational methods, systematically varying the quantum mechanics (QM) system size, dielectric constants, density functional, and basis sets. All methods were based on structures optimized with combined QM and molecular mechanics (QM/MM) approaches. The redox potentials were evaluated using 10 quality metrics. The b

Establishing action plans for sustainable mobility within companies

This study explores a collaborative project between various levels of public administration in southern Sweden, designed to encourage companies to adopt sustainable transportation practices. Conducted with the participation of researchers from Lund University, the project supports companies in developing and annually revising action plans that include specific sustainability goals, assigned respon

Green infrastructure has weak conceptual links with efficient biodiversity conservation

To reverse biodiversity loss, creating resilient ecological networks has been promoted in policy and practice. However, we argue that emphasising networks within policy without clear conservation prioritisations may direct focus away from ecological processes important for population persistence. We studied the rationale for resilient ecological networks represented in a policy context, by reviewi

Real-world experiences of adult individuals or caregivers of children who received teplizumab treatment in stage 2 type 1 diabetes

Aims: This study surveyed individuals and caregivers of children who received teplizumab at stage 2 type 1 diabetes (T1D) to garner real-world experiences and their health outlook for the future following treatment with the first approved disease-modifying immune therapy for delaying the onset of Stage 3 T1D. Materials and Methods: This was a cross-sectional, observational, online survey (conducte

Self-reported sleep disturbances and its determinants in people 1 year or more after stroke : A cross-sectional study

Background: Survivors of stroke commonly report sleep disturbances. Studies of sleep disturbances after stroke are mostly performed in the acute phase. An increased knowledge of sleep disturbances and its determinants a longer time after stroke is needed to improve treatment and rehabilitation. Objective: To assess survivors of stroke more than 1 year after stroke onset and (1) investigate self-re

Information capacity of quantum communication under natural physical assumptions

The quantum prepare-and-measure scenario has been studied under various physical assumptions on the emitted states. Here, we first discuss how different assumptions are conceptually and formally related. We then identify one that can serve as a relaxation of all others, corresponding to a limitation on the one-shot accessible information of the state ensemble. This motivates us to study the optima

Accuracy of a whole-body single-photon emission computed tomography with a thallium-bromide detector : Verification via Monte Carlo simulations

Background: Single-photon emission computed tomography (SPECT) devices equipped with cadmium–zinc–telluride (CZT) detectors achieve high contrast resolution because of their enhanced energy resolution. Recently, thallium bromide (TlBr) has gained attention as a detector material because of its high atomic number and density. Purpose: This study evaluated the clinical applicability of a SPECT syste

Financial and non-financial performance measurement at the municipal group level – Evidence from municipal budgets in Sweden

Purpose: This paper aims to explore Swedish municipalities’ adoption of politically decided goals and targets, within the budget document, that are formulated for the accounting unit of the municipal group. Design/methodology/approach: A regression analysis of the adoption of financial and non-financial performance measurement by 289 Swedish municipalities was performed, including eight independen

In situ Laser Fenestration of Visceral Endografts (InLoVE) : Midterm Outcomes from a Multicentre Study

Objective: Emergency complex abdominal aortic diseases are challenging to treat. During in situ laser fenestration (ISLF), aortic branches are covered and flow is restored by in situ fenestration of the stent graft, with promising midterm results. This study aimed to expand on the limited body of knowledge of midterm outcomes of ISLF in renovisceral aortic pathology in a multicentre setting. Metho

Application of Novel Plant Probiotics to Increase the Health Value of Ready-to-Eat Leafy Greens

Ready-to-eat (RTE) leafy greens offer an appealing way to integrate leafy greens into meals. Unfortunately, these leafy greens canget contaminated with human pathogens such as Salmonella, and Shiga toxin producing Escherichia coli (STEC) at any stage along themanufacturing chain, potentially leading to serious foodborne diseases. Currently, there is no single step in the production and processing

Quantitative measurement of aluminum atom number density around a burning micron-sized aluminum droplet using spatially resolved laser absorption spectroscopy

In this study, we demonstrate a successful application of laser absorption spectroscopy in an in-situ optical diagnostic system to map the radial distribution of the number density of vapor-phase aluminum (Al) atoms around a burning micron-sized Al droplet. This technique overcomes the challenges associated with the short optical path (at micron scale) and offers high sensitivity to Al atom concen